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The map label for this gene is siaT [H]

Identifier: 78357257

GI number: 78357257

Start: 2254144

End: 2255463

Strand: Reverse

Name: siaT [H]

Synonym: Dde_2214

Alternate gene names: 78357257

Gene position: 2255463-2254144 (Counterclockwise)

Preceding gene: 78357258

Following gene: 78357250

Centisome position: 60.46

GC content: 58.56

Gene sequence:

>1320_bases
ATGATGGATCCCACGATTGCGGGTATTTGCGGCATTGCTGCCATGATGGTGCTTTTCATGCTGCGCATGCCGGTGGCTTA
TGCCATGCTGCTGGTGGGGGTTGCCGGGTTCAGTATGCTTACCAGCGTCACCGGCGGGCTGAACATGCTGGGGCGGTCGG
TATATTCCACGTTTGCCTCGCACGAGCTGAGCACCATCCCTTTGTTCATTCTCATGGGGCAGATTGCTTTCAATGCGGGT
ATAAGCCGGCGGCTTTATGACACCGCGTATTGTTTTTTGGGCCATGTGCGCGGCGGGCTGGCCATGGCCACGGTTTCCGC
CTGTACGGCATTCGGCGCTGTCTGCGGATCCAGTCCGGCCACGGCGGCCACCATGGCCACAGTGGGCCTGCCCGAGATGA
AGCGCTTCGGATATTCGGACGAACTGGCCGCCGGCGCCGTGGCTTCCGGCGGCGGGCTGGGCATGATCATGCCGCCCAGT
GTTGTTCTGCTGGTTTACGGAGTGCTCACAGAGCAGTCCATAGGCGCTCTGTTCGTCGCCGGTATTCTGCCCGCCTTGCT
GCTTACCTTGCTTTTTATCGCGGCGGTTGCGGTGCAGTGCCTGCTGTACCCGCAGCACGGACCGGCAGGCCGGCGTTCGT
CATGGCGTTGCCGTCTGTGTTCACTTATGGGACTGGTGGACACTCTGCTTGTTTTTGCGCTTGTCATCGGCGGCATGTTC
TACGGCTGGTTCACCCCCACGGAGGCTGCTTCCATCGGCGTGCTCGGGGTGTTTGTGCTTGCCGTATCCAGAGGGCATCT
GGGATGGCGGGGTTTTGTCAAAGCCGTGGATGAGACCCTGCGCACATCATGCATGGTCATGCTGCTGATAGCCGGTGCCA
CCGTGTTCGGCAAATTTCTTGCCGTGACCCGTATTCCTTTTGACATTGCCGGCTGGGTGGGTGGTTTTGATCTGCCGGCC
TTTGCCGTTATGGGACTTGTGGTGGCCGTGTACTTTGTGGGCGGCTGCTTTATGGATTCACTGGCGCTGGTCATGCTGAC
CATACCGGTGTTCTATCCTCTGGTGCTCAATCTGGGGTACGACCCTGTCTGGTTCGGCATCATCATTGTGCTGGTAACTG
AAATGGGGGTCATCACTCCGCCGGTGGGTATAAATGTCTATGTTGTGTACGGCATTGCCCAGCAGGTTGTTCCGGGCGGT
ATCGCTCTCGAGAGTGTGTTCAAGGGGGTTCTGCCTTTTCTTGTGGCGGTGATTGCGGGCATTGCCCTGCTGCTTTGCTT
TCCGCAGATTGTCACCCTGTTGCCATCGCTGATGTATTGA

Upstream 100 bases:

>100_bases
AACTGCCGGAATATCTGGTAGTCGCTCTGGTGGGGCTGGGCGTTGTTGTGTTCGCGCTGCATCTGGTGTGCGACGTGCTG
CGGGCCGTACGGGGAGAAGC

Downstream 100 bases:

>100_bases
GAACGGTACAGCAAAAAACCGCCCCGTGGCATCACGGGGCGGTCTGTTTTTGTACGGCCGGTTGTCAGCGCAGCGAGGTG
CCTACACTGGGTGAATATCC

Product: TRAP dicarboxylate transporter subunit DctM

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MMDPTIAGICGIAAMMVLFMLRMPVAYAMLLVGVAGFSMLTSVTGGLNMLGRSVYSTFASHELSTIPLFILMGQIAFNAG
ISRRLYDTAYCFLGHVRGGLAMATVSACTAFGAVCGSSPATAATMATVGLPEMKRFGYSDELAAGAVASGGGLGMIMPPS
VVLLVYGVLTEQSIGALFVAGILPALLLTLLFIAAVAVQCLLYPQHGPAGRRSSWRCRLCSLMGLVDTLLVFALVIGGMF
YGWFTPTEAASIGVLGVFVLAVSRGHLGWRGFVKAVDETLRTSCMVMLLIAGATVFGKFLAVTRIPFDIAGWVGGFDLPA
FAVMGLVVAVYFVGGCFMDSLALVMLTIPVFYPLVLNLGYDPVWFGIIIVLVTEMGVITPPVGINVYVVYGIAQQVVPGG
IALESVFKGVLPFLVAVIAGIALLLCFPQIVTLLPSLMY

Sequences:

>Translated_439_residues
MMDPTIAGICGIAAMMVLFMLRMPVAYAMLLVGVAGFSMLTSVTGGLNMLGRSVYSTFASHELSTIPLFILMGQIAFNAG
ISRRLYDTAYCFLGHVRGGLAMATVSACTAFGAVCGSSPATAATMATVGLPEMKRFGYSDELAAGAVASGGGLGMIMPPS
VVLLVYGVLTEQSIGALFVAGILPALLLTLLFIAAVAVQCLLYPQHGPAGRRSSWRCRLCSLMGLVDTLLVFALVIGGMF
YGWFTPTEAASIGVLGVFVLAVSRGHLGWRGFVKAVDETLRTSCMVMLLIAGATVFGKFLAVTRIPFDIAGWVGGFDLPA
FAVMGLVVAVYFVGGCFMDSLALVMLTIPVFYPLVLNLGYDPVWFGIIIVLVTEMGVITPPVGINVYVVYGIAQQVVPGG
IALESVFKGVLPFLVAVIAGIALLLCFPQIVTLLPSLMY
>Mature_439_residues
MMDPTIAGICGIAAMMVLFMLRMPVAYAMLLVGVAGFSMLTSVTGGLNMLGRSVYSTFASHELSTIPLFILMGQIAFNAG
ISRRLYDTAYCFLGHVRGGLAMATVSACTAFGAVCGSSPATAATMATVGLPEMKRFGYSDELAAGAVASGGGLGMIMPPS
VVLLVYGVLTEQSIGALFVAGILPALLLTLLFIAAVAVQCLLYPQHGPAGRRSSWRCRLCSLMGLVDTLLVFALVIGGMF
YGWFTPTEAASIGVLGVFVLAVSRGHLGWRGFVKAVDETLRTSCMVMLLIAGATVFGKFLAVTRIPFDIAGWVGGFDLPA
FAVMGLVVAVYFVGGCFMDSLALVMLTIPVFYPLVLNLGYDPVWFGIIIVLVTEMGVITPPVGINVYVVYGIAQQVVPGG
IALESVFKGVLPFLVAVIAGIALLLCFPQIVTLLPSLMY

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=415, Percent_Identity=28.433734939759, Blast_Score=135, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 46087; Mature: 46087

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]