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The map label for this gene is xseA [H]

Identifier: 78357247

GI number: 78357247

Start: 2244408

End: 2245868

Strand: Reverse

Name: xseA [H]

Synonym: Dde_2204

Alternate gene names: 78357247

Gene position: 2245868-2244408 (Counterclockwise)

Preceding gene: 78357248

Following gene: 78357246

Centisome position: 60.21

GC content: 62.08

Gene sequence:

>1461_bases
ATGACAAAGATTTTTTCGGTCGGCGAAGTGACCCGCGGTATAAAAAATACGCTGGAGGCGGCGTATCCTTTTGTATGGGT
CAGGGGGCAGGTTTCCAACCTGTCGCGTCCGGCATCCGGTCATGTGTATTTTTCTCTCAAAGATGAAGACGCATCGCTTG
CCTGTGTGTGGTTTCGTCATGCGCAGCGCGGTGAAGAGACCTTTGACCCGCTTACCGGCGAGGTTTTTGACGACGGGCCG
CGCCCCGGGCTGGCCGCTGTCATGCGCAACGGGCAGGAGATGCTCTGCGCGGGCCGTGTGACGGTATACGGGCCGCGCGG
CACATATCAGCTTGTGGTCGAGCTTGCGCAGGATGTGGGGCTGGGCGAACTGCACCTGCGGTTTGAAGAGCTTAAGAAAA
AGCTGGCCGGTATGGGCTGGTTTGATGCCGCCCGCAAACGCCCGTTGCCGCGTCATCCCCTGCGTGTGGCTGTTGTTACT
GCGGCCACAGGCGCTGCCGTGCGTGATTTTGTGCGTATTGCGGCCGACAGGGGCAGCGGCTGTTCCATACGGATTTACCC
CGTGCCGGTGCAAGGGGATGATGCCCCGCCCCGTATTGCCGCCGCTCTGGAGCTTGCCGCCGCGCATGACTGGGCGCAGG
TTGTGGTGCTTATCCGCGGCGGCGGTTCGCTGGAAGACCTGTGGGCTTTTAATGACGAGCGTGTGGCAAAGGCTGTTTTT
GAAAGTCCTTTACCGGTGCTGACAGGTATCGGGCATGAGGTCGACACAGCCATAGCCGACATGGTGGCTGATGTCAGGGC
CGCGACACCGTCTCATGCGGCTCAGCTGCTGTGGCCGGAGCGTCAGGAGCTGGTACAGCGGCTTGATGATGCTTCCCAGC
TGCTTGACCGCGCATGGGAACTCGGTATGCAGGAACGTGAGAAAAGCGTGAAAGAGTGCGAACGTGCGCTGCACTGGCTT
TCTCCGCAGCGGTCGCTGGAACGGCTGGATGAACGTTTTGCCGAAGCCGTGCGGCGGCTGATGGCGGCCGCACAGGCACT
GACAGAACGCAAGGAACGCCGGCTGGCAGCAGAGACTGCATCGCTGCGGCATGCCTTTGGCCCTGCGGCGCTGGACACCG
GACTGCTTGCCGTGCGTCAGCTTGCGGCAAGGCTTGTGCGTGCCGGTGAATCTTTTGCGGAACGTGCCGCCGTGCGTCTG
GAGCGGGAAACGCTGCGGCTGAAAGCTGCGGACCCGCTGCTCCCTCTGGAGCGGGGGTACAGCATCTTGCAGCGTCCCGA
CGGCGGTTTTGTCCGCAGTGTGGCAGGGCTTGAGGCGGGGGATAACCTGCGGGTGCTGGTGCGTGACGGAGCGGCTGATG
TGGCGGTGACGGCTGTGCACGCCGTTTCTGCGGCAGAGGCCGCCGGTATGCCGGCAGGTGGGAAAAAAATCAAAGGAGAC
CGTTCCGATGATGAGTCATGA

Upstream 100 bases:

>100_bases
TACGGGCGGTTTTGCATGGCGCTGCAAGGCGCATCTCAACGGGGTCGACCGCGTGCGGACGGTGCCCCGCATGTTTTTAG
ATATGACCGGATATTAGGGT

Downstream 100 bases:

>100_bases
CCGTTTGTTTTCGCGCAGTGGTGGTGCCCGGCAGGGCAGACCGCAGGCATTTTTCTTTTCCGGCGGGATTGTCTTTCTTT
CCGTGCTGGCGCTTTTTCTG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MTKIFSVGEVTRGIKNTLEAAYPFVWVRGQVSNLSRPASGHVYFSLKDEDASLACVWFRHAQRGEETFDPLTGEVFDDGP
RPGLAAVMRNGQEMLCAGRVTVYGPRGTYQLVVELAQDVGLGELHLRFEELKKKLAGMGWFDAARKRPLPRHPLRVAVVT
AATGAAVRDFVRIAADRGSGCSIRIYPVPVQGDDAPPRIAAALELAAAHDWAQVVVLIRGGGSLEDLWAFNDERVAKAVF
ESPLPVLTGIGHEVDTAIADMVADVRAATPSHAAQLLWPERQELVQRLDDASQLLDRAWELGMQEREKSVKECERALHWL
SPQRSLERLDERFAEAVRRLMAAAQALTERKERRLAAETASLRHAFGPAALDTGLLAVRQLAARLVRAGESFAERAAVRL
ERETLRLKAADPLLPLERGYSILQRPDGGFVRSVAGLEAGDNLRVLVRDGAADVAVTAVHAVSAAEAAGMPAGGKKIKGD
RSDDES

Sequences:

>Translated_486_residues
MTKIFSVGEVTRGIKNTLEAAYPFVWVRGQVSNLSRPASGHVYFSLKDEDASLACVWFRHAQRGEETFDPLTGEVFDDGP
RPGLAAVMRNGQEMLCAGRVTVYGPRGTYQLVVELAQDVGLGELHLRFEELKKKLAGMGWFDAARKRPLPRHPLRVAVVT
AATGAAVRDFVRIAADRGSGCSIRIYPVPVQGDDAPPRIAAALELAAAHDWAQVVVLIRGGGSLEDLWAFNDERVAKAVF
ESPLPVLTGIGHEVDTAIADMVADVRAATPSHAAQLLWPERQELVQRLDDASQLLDRAWELGMQEREKSVKECERALHWL
SPQRSLERLDERFAEAVRRLMAAAQALTERKERRLAAETASLRHAFGPAALDTGLLAVRQLAARLVRAGESFAERAAVRL
ERETLRLKAADPLLPLERGYSILQRPDGGFVRSVAGLEAGDNLRVLVRDGAADVAVTAVHAVSAAEAAGMPAGGKKIKGD
RSDDES
>Mature_485_residues
TKIFSVGEVTRGIKNTLEAAYPFVWVRGQVSNLSRPASGHVYFSLKDEDASLACVWFRHAQRGEETFDPLTGEVFDDGPR
PGLAAVMRNGQEMLCAGRVTVYGPRGTYQLVVELAQDVGLGELHLRFEELKKKLAGMGWFDAARKRPLPRHPLRVAVVTA
ATGAAVRDFVRIAADRGSGCSIRIYPVPVQGDDAPPRIAAALELAAAHDWAQVVVLIRGGGSLEDLWAFNDERVAKAVFE
SPLPVLTGIGHEVDTAIADMVADVRAATPSHAAQLLWPERQELVQRLDDASQLLDRAWELGMQEREKSVKECERALHWLS
PQRSLERLDERFAEAVRRLMAAAQALTERKERRLAAETASLRHAFGPAALDTGLLAVRQLAARLVRAGESFAERAAVRLE
RETLRLKAADPLLPLERGYSILQRPDGGFVRSVAGLEAGDNLRVLVRDGAADVAVTAVHAVSAAEAAGMPAGGKKIKGDR
SDDES

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=462, Percent_Identity=34.8484848484849, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 52912; Mature: 52781

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIFSVGEVTRGIKNTLEAAYPFVWVRGQVSNLSRPASGHVYFSLKDEDASLACVWFRH
CCCCCCHHHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCEEEEEEECCCCCEEEHHHHH
AQRGEETFDPLTGEVFDDGPRPGLAAVMRNGQEMLCAGRVTVYGPRGTYQLVVELAQDVG
HHCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHCC
LGELHLRFEELKKKLAGMGWFDAARKRPLPRHPLRVAVVTAATGAAVRDFVRIAADRGSG
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCC
CSIRIYPVPVQGDDAPPRIAAALELAAAHDWAQVVVLIRGGGSLEDLWAFNDERVAKAVF
CEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHH
ESPLPVLTGIGHEVDTAIADMVADVRAATPSHAAQLLWPERQELVQRLDDASQLLDRAWE
HCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LGMQEREKSVKECERALHWLSPQRSLERLDERFAEAVRRLMAAAQALTERKERRLAAETA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRHAFGPAALDTGLLAVRQLAARLVRAGESFAERAAVRLERETLRLKAADPLLPLERGY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEECCCCCCCHHHCC
SILQRPDGGFVRSVAGLEAGDNLRVLVRDGAADVAVTAVHAVSAAEAAGMPAGGKKIKGD
HHHCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RSDDES
CCCCCC
>Mature Secondary Structure 
TKIFSVGEVTRGIKNTLEAAYPFVWVRGQVSNLSRPASGHVYFSLKDEDASLACVWFRH
CCCCCHHHHHHHHHHHHHHHCCEEEEECCHHCCCCCCCCEEEEEEECCCCCEEEHHHHH
AQRGEETFDPLTGEVFDDGPRPGLAAVMRNGQEMLCAGRVTVYGPRGTYQLVVELAQDVG
HHCCCHHCCCCCCCCCCCCCCCCHHHHHHCCCCEEEECCEEEECCCCHHHHHHHHHHHCC
LGELHLRFEELKKKLAGMGWFDAARKRPLPRHPLRVAVVTAATGAAVRDFVRIAADRGSG
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCC
CSIRIYPVPVQGDDAPPRIAAALELAAAHDWAQVVVLIRGGGSLEDLWAFNDERVAKAVF
CEEEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHCCCHHHHHHHHH
ESPLPVLTGIGHEVDTAIADMVADVRAATPSHAAQLLWPERQELVQRLDDASQLLDRAWE
HCCCHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LGMQEREKSVKECERALHWLSPQRSLERLDERFAEAVRRLMAAAQALTERKERRLAAETA
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLRHAFGPAALDTGLLAVRQLAARLVRAGESFAERAAVRLERETLRLKAADPLLPLERGY
HHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHEEECCCCCCCHHHCC
SILQRPDGGFVRSVAGLEAGDNLRVLVRDGAADVAVTAVHAVSAAEAAGMPAGGKKIKGD
HHHCCCCCCHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RSDDES
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA