Click here to switch to the map view.

The map label for this gene is yfdZ [C]

Identifier: 78357235

GI number: 78357235

Start: 2231824

End: 2232981

Strand: Reverse

Name: yfdZ [C]

Synonym: Dde_2192

Alternate gene names: 78357235

Gene position: 2232981-2231824 (Counterclockwise)

Preceding gene: 78357236

Following gene: 78357234

Centisome position: 59.86

GC content: 55.01

Gene sequence:

>1158_bases
ATGAAGGAAACCGGCAGAACGGCGGGTATAAAGCCTTTTTATGCAATGGATGTGCTTGAGCGGGCTCAGGAGCTGGAAAG
GCAGGGCGCCGATGTTATCCACCTTGCTCTGGGCGAGCCGGATTTTGATGTGCCGGAACCGGTCAGGCAGGCGCTGGTGC
AGGCTGTGGAGGGCGGACACACCCACTACACGGGCAGCATGGGCATGCTTGAGTTGCGACAGGCCATCGCAAAGGACTAT
CGCCGCCGGTATGGTGTTGATGTTTCTCCGGAACGCATTGCCGTGACCAGCGGCACATCTCCTGCCATGTTTATGCTGTT
CGGTGCCTTATTGCAGCAGGGCGACGAGGTCATCATTTCCGACCCTCATTACGCCTGCTACCCCAGCTTTATCAGTTTTG
CAGGCGGGGTACCGGTAAAAGTCCGCGTTTATGAGGAAGACGGCTTTCAGTACCGTTTGGATGCCATCAAGGCCAAACTG
ACCGGGCGTACCAGAGCCATTTTTATCAATTCCCCTTCCAATCCGACAGGTAACCAGTTGCCGGCAGACAGGATGCGCCG
CATTGCCTCTCTGGGAATTCCCGTCATCAGCGATGAGATTTATCACGGGCTGGAATATGGTGAAAAAGAGCACACGATTC
TTGAATTCACAGATAACGCTTTCGTGTTCAACGGTTTTTCAAAGCTGTATGCCATGACCGGACTCCGTCTGGGGTATGTT
ATTGCTCCGGATGCATGGGTTCCGGTGCTGCGCAAGCTGTGCCAGAATTTTTTCATCTCTCCCAACTCCGTCTCGCAGCA
TGCGGGTGTTGCGGCTTTGACACAATGTGATGCCGATGTGGCCCGTATGCGCATTATTTACGACGAGCGCCGCAAATTTA
TGATCCGCCGTCTGCGCGAGATGGGGTTCGGCATCACCGTGGAGCCCACGGGAGCATTCTATGTGCTTGCCAATGCCCGT
TTTCTTTCAGCGGATTCCTATGCTCTGGCATTTGAAATACTGGAGCAGGCACACGTGGGTGTGACGCCGGGCATTGACTT
CGGCGAAGGGGCCGAGGGGTACCTGCGTTTTTCCTATGCCAGCTCTCTGGAAAAGATTCATGAGGCCATGAACCGCCTGG
AGCAGTTTGTACGCAGCAGAACCGGTTGCGCGTGCTGA

Upstream 100 bases:

>100_bases
TGACGACATCAGGGCCGGAGTGCTTGCGGCTGTTGCCGTATAATGGAAAAACGAAGCACATGTGCGGAATGTCCGCCATG
ACGCAGAACGGAGAAAGTGC

Downstream 100 bases:

>100_bases
CGGCTATGGGCGGCGCAGACGATCCTTATGCCCGTATGGCGCGGCATTATGACAGGGTGCTGAACCCTGTGCTTGATCCG
GTGCGCCGCCGGATAGCCTG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKETGRTAGIKPFYAMDVLERAQELERQGADVIHLALGEPDFDVPEPVRQALVQAVEGGHTHYTGSMGMLELRQAIAKDY
RRRYGVDVSPERIAVTSGTSPAMFMLFGALLQQGDEVIISDPHYACYPSFISFAGGVPVKVRVYEEDGFQYRLDAIKAKL
TGRTRAIFINSPSNPTGNQLPADRMRRIASLGIPVISDEIYHGLEYGEKEHTILEFTDNAFVFNGFSKLYAMTGLRLGYV
IAPDAWVPVLRKLCQNFFISPNSVSQHAGVAALTQCDADVARMRIIYDERRKFMIRRLREMGFGITVEPTGAFYVLANAR
FLSADSYALAFEILEQAHVGVTPGIDFGEGAEGYLRFSYASSLEKIHEAMNRLEQFVRSRTGCAC

Sequences:

>Translated_385_residues
MKETGRTAGIKPFYAMDVLERAQELERQGADVIHLALGEPDFDVPEPVRQALVQAVEGGHTHYTGSMGMLELRQAIAKDY
RRRYGVDVSPERIAVTSGTSPAMFMLFGALLQQGDEVIISDPHYACYPSFISFAGGVPVKVRVYEEDGFQYRLDAIKAKL
TGRTRAIFINSPSNPTGNQLPADRMRRIASLGIPVISDEIYHGLEYGEKEHTILEFTDNAFVFNGFSKLYAMTGLRLGYV
IAPDAWVPVLRKLCQNFFISPNSVSQHAGVAALTQCDADVARMRIIYDERRKFMIRRLREMGFGITVEPTGAFYVLANAR
FLSADSYALAFEILEQAHVGVTPGIDFGEGAEGYLRFSYASSLEKIHEAMNRLEQFVRSRTGCAC
>Mature_385_residues
MKETGRTAGIKPFYAMDVLERAQELERQGADVIHLALGEPDFDVPEPVRQALVQAVEGGHTHYTGSMGMLELRQAIAKDY
RRRYGVDVSPERIAVTSGTSPAMFMLFGALLQQGDEVIISDPHYACYPSFISFAGGVPVKVRVYEEDGFQYRLDAIKAKL
TGRTRAIFINSPSNPTGNQLPADRMRRIASLGIPVISDEIYHGLEYGEKEHTILEFTDNAFVFNGFSKLYAMTGLRLGYV
IAPDAWVPVLRKLCQNFFISPNSVSQHAGVAALTQCDADVARMRIIYDERRKFMIRRLREMGFGITVEPTGAFYVLANAR
FLSADSYALAFEILEQAHVGVTPGIDFGEGAEGYLRFSYASSLEKIHEAMNRLEQFVRSRTGCAC

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=317, Percent_Identity=28.7066246056782, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI169881279, Length=317, Percent_Identity=28.7066246056782, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI56713254, Length=333, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI56713256, Length=333, Percent_Identity=27.027027027027, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI4507369, Length=228, Percent_Identity=23.6842105263158, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI169881281, Length=228, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI1788722, Length=368, Percent_Identity=27.7173913043478, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786816, Length=361, Percent_Identity=28.5318559556787, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=25.7142857142857, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787909, Length=374, Percent_Identity=23.2620320855615, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI48994949, Length=350, Percent_Identity=22, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17567369, Length=327, Percent_Identity=26.2996941896024, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994472, Length=255, Percent_Identity=27.4509803921569, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=255, Percent_Identity=27.4509803921569, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=367, Percent_Identity=24.5231607629428, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=23.7373737373737, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28573069, Length=313, Percent_Identity=26.1980830670927, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646114, Length=313, Percent_Identity=26.1980830670927, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573067, Length=313, Percent_Identity=26.1980830670927, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28573065, Length=313, Percent_Identity=26.1980830670927, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18859735, Length=373, Percent_Identity=24.3967828418231, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42868; Mature: 42868

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKETGRTAGIKPFYAMDVLERAQELERQGADVIHLALGEPDFDVPEPVRQALVQAVEGGH
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
THYTGSMGMLELRQAIAKDYRRRYGVDVSPERIAVTSGTSPAMFMLFGALLQQGDEVIIS
CEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEE
DPHYACYPSFISFAGGVPVKVRVYEEDGFQYRLDAIKAKLTGRTRAIFINSPSNPTGNQL
CCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCCC
PADRMRRIASLGIPVISDEIYHGLEYGEKEHTILEFTDNAFVFNGFSKLYAMTGLRLGYV
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEECCHHHHHHHHCCEEEEE
IAPDAWVPVLRKLCQNFFISPNSVSQHAGVAALTQCDADVARMRIIYDERRKFMIRRLRE
ECCCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MGFGITVEPTGAFYVLANARFLSADSYALAFEILEQAHVGVTPGIDFGEGAEGYLRFSYA
CCCCEEECCCCCEEEEECCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHH
SSLEKIHEAMNRLEQFVRSRTGCAC
HHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKETGRTAGIKPFYAMDVLERAQELERQGADVIHLALGEPDFDVPEPVRQALVQAVEGGH
CCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCC
THYTGSMGMLELRQAIAKDYRRRYGVDVSPERIAVTSGTSPAMFMLFGALLQQGDEVIIS
CEEECCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEE
DPHYACYPSFISFAGGVPVKVRVYEEDGFQYRLDAIKAKLTGRTRAIFINSPSNPTGNQL
CCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEHHHHHHHCCCCEEEEEEECCCCCCCCCC
PADRMRRIASLGIPVISDEIYHGLEYGEKEHTILEFTDNAFVFNGFSKLYAMTGLRLGYV
CHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEEECCEEEECCHHHHHHHHCCEEEEE
IAPDAWVPVLRKLCQNFFISPNSVSQHAGVAALTQCDADVARMRIIYDERRKFMIRRLRE
ECCCCHHHHHHHHHHHHCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
MGFGITVEPTGAFYVLANARFLSADSYALAFEILEQAHVGVTPGIDFGEGAEGYLRFSYA
CCCCEEECCCCCEEEEECCEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEHHH
SSLEKIHEAMNRLEQFVRSRTGCAC
HHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]