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The map label for this gene is ywlF [H]

Identifier: 78357163

GI number: 78357163

Start: 2169654

End: 2170094

Strand: Direct

Name: ywlF [H]

Synonym: Dde_2120

Alternate gene names: 78357163

Gene position: 2169654-2170094 (Clockwise)

Preceding gene: 78357162

Following gene: 78357164

Centisome position: 58.16

GC content: 55.56

Gene sequence:

>441_bases
ATGGCCAAGCAAGTAATCATCGGCTCCGATCATGCCGGTTTCAGCCTCAAGGAACTTCTTGTTTCTGAACTTACCAAAAG
CGGGTACGATGTACACGACATGGGACCGGCAACCGCGGAAAGCTGTGACTATCCGCTTTTTGCGCAGAAAGTATGCGAAC
GGGTTCTGCAGCAAAAAGCACAGGGAATTCTCATCTGCGGAACCGGCATAGGCATGTCCATGGCTGCCAACCGCATTGAC
GGCATACGCGCCGCACTCTGTACCACCGAATTCCATGCCAGGGCCACCCGTCTGCACAACAATGCCAATGTTCTCTGTCT
GGGCGAACGCGTGACCGGCCCCGGTGTTGCACTTGAGCTTGCCAGGCTTTTTCTTGAAACCGAGTTTGAAGGCGGGCGGC
ATCAGCGCCGCATCGACCTGTTTGATTCTGCCAGCGCCTGA

Upstream 100 bases:

>100_bases
GGCACGTTTTATAGAAAAACAGCGGCTGAAGTATGAAAAAAGACATCCGGCCGACAACGGGTCAGTCCCGCAGGCAAACC
AGTAAAGACAAGGAAACGCA

Downstream 100 bases:

>100_bases
AAACAGCTGGTTCCTTCCGGAGACGATACAGAATGCAGCTATATAATACACTGACCCGAAAAAAAGAAAAATTTATCCCC
CAGCGTGAAGGTAAAGCCAG

Product: ribose-5-phosphate isomerase

Products: D-ribulose 5-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MAKQVIIGSDHAGFSLKELLVSELTKSGYDVHDMGPATAESCDYPLFAQKVCERVLQQKAQGILICGTGIGMSMAANRID
GIRAALCTTEFHARATRLHNNANVLCLGERVTGPGVALELARLFLETEFEGGRHQRRIDLFDSASA

Sequences:

>Translated_146_residues
MAKQVIIGSDHAGFSLKELLVSELTKSGYDVHDMGPATAESCDYPLFAQKVCERVLQQKAQGILICGTGIGMSMAANRID
GIRAALCTTEFHARATRLHNNANVLCLGERVTGPGVALELARLFLETEFEGGRHQRRIDLFDSASA
>Mature_145_residues
AKQVIIGSDHAGFSLKELLVSELTKSGYDVHDMGPATAESCDYPLFAQKVCERVLQQKAQGILICGTGIGMSMAANRIDG
IRAALCTTEFHARATRLHNNANVLCLGERVTGPGVALELARLFLETEFEGGRHQRRIDLFDSASA

Specific function: In Addition To Its Activity On D-Ribose 5-Phosphate It Probably Also Has Activity On D-Allose 6-Phosphate. [C]

COG id: COG0698

COG function: function code G; Ribose 5-phosphate isomerase RpiB

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lacAB/rpiB family [H]

Homologues:

Organism=Escherichia coli, GI1790528, Length=138, Percent_Identity=42.7536231884058, Blast_Score=120, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003500
- InterPro:   IPR004785 [H]

Pfam domain/function: PF02502 LacAB_rpiB [H]

EC number: 5.3.1.6

Molecular weight: Translated: 15791; Mature: 15660

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQVIIGSDHAGFSLKELLVSELTKSGYDVHDMGPATAESCDYPLFAQKVCERVLQQKA
CCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QGILICGTGIGMSMAANRIDGIRAALCTTEFHARATRLHNNANVLCLGERVTGPGVALEL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
ARLFLETEFEGGRHQRRIDLFDSASA
HHHHHHHCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure 
AKQVIIGSDHAGFSLKELLVSELTKSGYDVHDMGPATAESCDYPLFAQKVCERVLQQKA
CCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QGILICGTGIGMSMAANRIDGIRAALCTTEFHARATRLHNNANVLCLGERVTGPGVALEL
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHH
ARLFLETEFEGGRHQRRIDLFDSASA
HHHHHHHCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 4.4 {D-ribose} 0.83 {D-ribose} [C]

Substrates: D-ribose 5-phosphate

Specific reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate

General reaction: Intramolecular oxidoreduction; Isomerization [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]