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The map label for this gene is cheB2

Identifier: 78357147

GI number: 78357147

Start: 2152759

End: 2153829

Strand: Reverse

Name: cheB2

Synonym: Dde_2104

Alternate gene names: 78357147

Gene position: 2153829-2152759 (Counterclockwise)

Preceding gene: 78357148

Following gene: 78357144

Centisome position: 57.74

GC content: 57.33

Gene sequence:

>1071_bases
ATGGCACGACACATCAAGGTTCTTATTGTTGATGATTCAGCCCTTGTCCGGCAGACGCTTACCGATATCTTTTCTGCCGA
TCCAGAACTGGAAGTGGTGGGAACTGCCTCTGACCCCTTTGTAGCTGTCAAACGCATGGAAACGGTGGTGCCCGATGTGA
TTCTGCTGGATGTGGCCATGCCACGCATGGACGGGCTGACCTTTCTGCGCAAGATAATGAGTCAGCATCCCATTCCGGTG
GTTATCTGTTCTGCCGTGACGGAGCAGGGAGCTGAAGCCTCCTTTAAGGCCATGGAATACGGCGCCGTTGAAATTATTCA
GAAGCCGAAAGTCAGTACCAAGCAGTTTCTCGAAGAATCCAGCATAAGAATATGCGACGCAGTCAAGGCCGCTGCCCGCG
CCCAGTTGCGCAAGCTGGCGGCAAAGCGTTTTGAAGTTACCCCCAAGCTGTCGGCCGATGCCATGCTGCCGGCCAATGCC
GGAAGGTCCGTCGTGCAGCGAACGGAAAAGGTTGTGGTTGTGGGGGCCTCCACAGGCGGAACCGAAGCTCTGCGGGTTCT
GCTGGAAGCCATGCCGCCGGACTGTCCGCCCATTGCCATTGTGCAGCATATGCCTGAACATTTTACCGCGGCATTTGCCG
GCAGACTCAATTCCACCTGCCGCATACAGGTGAAGGAAGCTTCTGACGGTGATGTGATGCAGAGAGGACAGGCGCTTATT
GCTCCCGGCAATCTGCATCTGCTGCTAAAGCGTTCGGGCAGCCGTTACTATGTGGAGACCAAGGAAGGTCCGCTTGTGCG
GCGGCATCGTCCTTCCGTGGATGTGCTGTTCCGCTCCGCGGCCCGCTATGCGGGAAACAATGCCGTGGCAGCCATTATGA
CCGGCATGGGGGATGACGGAGCCGCAGGCATGAAAGAGCTGCATGAAACCGGCGCCTATACCATTGCGCAGGACGAAGCT
ACCTGTGTGGTGTACGGTATGCCGCATGAAGCCGTGAAGCTGGGCGGGGTGGATGCCGTTCTGCCGCTGGGAGCACTGGC
TGCGGCGATTGTTAAAGCCTGCAACAGCTGA

Upstream 100 bases:

>100_bases
GATGGCCACCTATTCATCGGTCATTCCGAAAGCCTGTCAGGAATGGCTCTTCCGCTGGAGCAGATTGCCCCGACCGTCTA
CAGGAGAGTGTAGGAACACC

Downstream 100 bases:

>100_bases
AAATCTGCTGCGGCAGCACACCATGTCCATGTGTGTTGTCAATTTCTTACGGAATCATTGTCTTTTCTGATACCTTGCGG
CTGCAAGATTTTTTTGAACC

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAMPRMDGLTFLRKIMSQHPIPV
VICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEESSIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANA
GRSVVQRTEKVVVVGASTGGTEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALI
APGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDGAAGMKELHETGAYTIAQDEA
TCVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS

Sequences:

>Translated_356_residues
MARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAMPRMDGLTFLRKIMSQHPIPV
VICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEESSIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANA
GRSVVQRTEKVVVVGASTGGTEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALI
APGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDGAAGMKELHETGAYTIAQDEA
TCVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS
>Mature_355_residues
ARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAMPRMDGLTFLRKIMSQHPIPVV
ICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEESSIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANAG
RSVVQRTEKVVVVGASTGGTEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALIA
PGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDGAAGMKELHETGAYTIAQDEAT
CVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS

Specific function: Involved in the modulation of the chemotaxis system; catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR

COG id: COG2201

COG function: function code NT; Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain

Homologues:

Organism=Escherichia coli, GI1788192, Length=339, Percent_Identity=47.4926253687316, Blast_Score=319, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CHEB2_DESDG (Q30ZJ5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388596.1
- ProteinModelPortal:   Q30ZJ5
- SMR:   Q30ZJ5
- STRING:   Q30ZJ5
- GeneID:   3757112
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2104
- NMPDR:   fig|207559.3.peg.2064
- eggNOG:   COG2201
- HOGENOM:   HBG705324
- OMA:   AENNDTV
- ProtClustDB:   CLSK830253
- BioCyc:   DDES207559:DDE_2104-MONOMER
- GO:   GO:0005737
- GO:   GO:0006935
- HAMAP:   MF_00099
- InterPro:   IPR011006
- InterPro:   IPR008248
- InterPro:   IPR000673
- InterPro:   IPR001789
- Gene3D:   G3DSA:3.40.50.180
- PIRSF:   PIRSF000876
- SMART:   SM00448

Pfam domain/function: PF01339 CheB_methylest; PF00072 Response_reg; SSF52738 Chemotax_RR_pGlu_Me-esterase; SSF52172 CheY_like

EC number: =3.1.1.61

Molecular weight: Translated: 38051; Mature: 37920

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: PS50122 CHEB; PS50110 RESPONSE_REGULATORY

Important sites: ACT_SITE 177-177 ACT_SITE 203-203 ACT_SITE 299-299

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAM
CCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHEEHHHC
PRMDGLTFLRKIMSQHPIPVVICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEES
CCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHCCHHHHHCCCCCCHHHHHHHC
SIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANAGRSVVQRTEKVVVVGASTGG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCC
TEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALI
HHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCEEE
APGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDG
ECCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
AAGMKELHETGAYTIAQDEATCVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS
HHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARHIKVLIVDDSALVRQTLTDIFSADPELEVVGTASDPFVAVKRMETVVPDVILLDVAM
CCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCHHHEEHHHC
PRMDGLTFLRKIMSQHPIPVVICSAVTEQGAEASFKAMEYGAVEIIQKPKVSTKQFLEES
CCCCHHHHHHHHHHCCCCCEEEEEHHHCCCCCCHHHHHHCCHHHHHCCCCCCHHHHHHHC
SIRICDAVKAAARAQLRKLAAKRFEVTPKLSADAMLPANAGRSVVQRTEKVVVVGASTGG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCEEEEEECCCCC
TEALRVLLEAMPPDCPPIAIVQHMPEHFTAAFAGRLNSTCRIQVKEASDGDVMQRGQALI
HHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHCCCCEEEEEEEECCCCHHHHCCCEEE
APGNLHLLLKRSGSRYYVETKEGPLVRRHRPSVDVLFRSAARYAGNNAVAAIMTGMGDDG
ECCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
AAGMKELHETGAYTIAQDEATCVVYGMPHEAVKLGGVDAVLPLGALAAAIVKACNS
HHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA