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The map label for this gene is pgsA [H]

Identifier: 78357117

GI number: 78357117

Start: 2116304

End: 2116855

Strand: Reverse

Name: pgsA [H]

Synonym: Dde_2074

Alternate gene names: 78357117

Gene position: 2116855-2116304 (Counterclockwise)

Preceding gene: 78357118

Following gene: 78357116

Centisome position: 56.75

GC content: 51.81

Gene sequence:

>552_bases
ATGCTTACCTTGGCAAATAAAATCACGCTGTTCCGTATTGTCATTGTGCCCCTGATTGTTGTTTTTCTGTATTTTCCCGG
TCGGATAACCTGTCTGCTGGCCATGCTGGGTTTCATACTTGCCGCGCTTTCAGACATGGTGGACGGGCACATTGCAAGAC
GCTCCAACACGGTGACCAGCTTTGGTAAATTTCTTGATCCGCTGGCGGACAAGCTGCTTATCAGTTCGGTACTTGTCATG
CTGTCCGCGCTGGGCTGGGTGCCTGCATGGGTTGTTATTGTCATTATCTGCCGCGAGCTTATGGTTACAGGGCTGCGCGC
CATTGCCGCAGACGAAGGCGTGGTCATTGCCGCCGATAAATTCGGCAAGATGAAAACCGTGCTTCAGATGCTGGCTTTGA
CCCCGCTGCTTCTGCATTACCCGTGGTTCGGATTCGACCCTAACCCCGCGGGACAGTTTCTGCTTTACATGGCGTTGATT
CTCACGGTATTTTCTGGTGGAAACTACCTGTATGCGTTTTATAAAAACTGGCGCACGGCGGATGCCGGTTAA

Upstream 100 bases:

>100_bases
GCTGTTTTATGCCGCCCGCTGCGGGTCGCCAGTTCTGTTTTTTTGCTGTATAGCTTTTTTGTGCCAATATATTGTAATGT
GACATGGGGGTCAGTTTCCG

Downstream 100 bases:

>100_bases
TAGCCGGCAGGCGCGGTTTTCCGCGTTGTTCAGAGGCTGCAGGTTCTCAGGAGAGTGATCGTGCAGGAACATGACGAATT
GCAGAGCCGCTTGCGGAACT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MLTLANKITLFRIVIVPLIVVFLYFPGRITCLLAMLGFILAALSDMVDGHIARRSNTVTSFGKFLDPLADKLLISSVLVM
LSALGWVPAWVVIVIICRELMVTGLRAIAADEGVVIAADKFGKMKTVLQMLALTPLLLHYPWFGFDPNPAGQFLLYMALI
LTVFSGGNYLYAFYKNWRTADAG

Sequences:

>Translated_183_residues
MLTLANKITLFRIVIVPLIVVFLYFPGRITCLLAMLGFILAALSDMVDGHIARRSNTVTSFGKFLDPLADKLLISSVLVM
LSALGWVPAWVVIVIICRELMVTGLRAIAADEGVVIAADKFGKMKTVLQMLALTPLLLHYPWFGFDPNPAGQFLLYMALI
LTVFSGGNYLYAFYKNWRTADAG
>Mature_183_residues
MLTLANKITLFRIVIVPLIVVFLYFPGRITCLLAMLGFILAALSDMVDGHIARRSNTVTSFGKFLDPLADKLLISSVLVM
LSALGWVPAWVVIVIICRELMVTGLRAIAADEGVVIAADKFGKMKTVLQMLALTPLLLHYPWFGFDPNPAGQFLLYMALI
LTVFSGGNYLYAFYKNWRTADAG

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=174, Percent_Identity=36.2068965517241, Blast_Score=95, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24650130, Length=105, Percent_Identity=34.2857142857143, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650126, Length=105, Percent_Identity=34.2857142857143, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650128, Length=105, Percent_Identity=34.2857142857143, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20189; Mature: 20189

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLANKITLFRIVIVPLIVVFLYFPGRITCLLAMLGFILAALSDMVDGHIARRSNTVTS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FGKFLDPLADKLLISSVLVMLSALGWVPAWVVIVIICRELMVTGLRAIAADEGVVIAADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
FGKMKTVLQMLALTPLLLHYPWFGFDPNPAGQFLLYMALILTVFSGGNYLYAFYKNWRTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DAG
CCC
>Mature Secondary Structure
MLTLANKITLFRIVIVPLIVVFLYFPGRITCLLAMLGFILAALSDMVDGHIARRSNTVTS
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
FGKFLDPLADKLLISSVLVMLSALGWVPAWVVIVIICRELMVTGLRAIAADEGVVIAADK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHH
FGKMKTVLQMLALTPLLLHYPWFGFDPNPAGQFLLYMALILTVFSGGNYLYAFYKNWRTA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCC
DAG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]