Click here to switch to the map view.

The map label for this gene is udg [H]

Identifier: 78357085

GI number: 78357085

Start: 2084732

End: 2086069

Strand: Reverse

Name: udg [H]

Synonym: Dde_2042

Alternate gene names: 78357085

Gene position: 2086069-2084732 (Counterclockwise)

Preceding gene: 78357093

Following gene: 78357083

Centisome position: 55.92

GC content: 55.75

Gene sequence:

>1338_bases
ATGAACGTTTGTATTGTCGGTACTGGCTATGTAGGACTTGTCAGCGCCGCCTGCTTTGCTGAAATGGGTAATACCGTCCG
TTGCGTGGACGTGAATCCCGAGGTGGTCGAAACGCTGAAAGCCGGCAAGGTGCATATTTACGAGCCGGGACTGGAAGAAC
TTGTACGCCGCAACTACGCAGAGGGGCGCCTGCAGTTTACCACCAGTCTTGAAGACGGGTTGAAGGACTCGCTTTTCGTG
TTCATCACTGTGGGTACCCCCTCCCGCGATGATGGCTCCTGCGACCTTGGATTTGTGGAACAGGTGGCCCGTCAGGTGGG
CGCCGGCATGACTGACAGAAAAATAGTGGTTGATAAATCCACAGTACCCGTGGGTACCGCTGACAAGGTTCGCGCCATTA
TCGCCGCGGAACTGGAAAAGCGCGGGGTGGACATTCCGTTCGACGTGGTTTCCAACCCCGAGTTCCTCAAGGAAGGCGAT
GCGGTCAACGATTTCATGAAGCCTGACCGGGTGGTGGTGGGAACCGACAGCGCCGAAACGGCAGAATACCTTAAGCAGCT
GTATGCGCCGTTTGCCCGCAGTCGTGAAAAGCTTATTGTTATGGGCGTGCGCAGTGCTGAAATGACCAAATATGCGGCCA
ACTGCATGCTTGCCACCAAAATTTCGTTCATTAACGAGATCGCCACGCTGTGCGAGCGTGTGGGGGCAGATGTGCGCGAT
GTGCGTACGGGTATAGGTTCAGACCACCGTATCGGCTACCATTTCATTTATCCGGGAGTGGGCTACGGCGGTTCCTGCTT
CCCCAAAGACGTCAAGGCACTCATTCATACCGCACGGGAGTACGGATTCAGACCCCAGTTGCTGGAAGCTGTGGAGGATG
TGAACTACCGGCAGAAAAAACACATGGCTGAGCGGATTCTGGAATACTTTGCCCCGCAGGGCGGAGTGCAGGGCAAGACC
ATCGCCTTGTGGGGGCTGGCATTCAAGGCCAATACTGATGACATGCGCGAAGCGGCAGCCCTGACTATAATACAGGAACT
TACCGCGCAGGGCATGAAGGTTCAGGCATACGACCCCGTGGCTGCCGACAATGCACGTGCACTGCTGGCCGATAATCCTC
TGGTTACCATTGTGGATGAACAGTACGAAGCTGTGGAAGGCGCGCAGGCTCTGCTGGTGGTCACCGAGTGGAATCAGTTC
CGTAATCCTGATTTCGGCCGCGTACGCAAGTCACTTACCGCGCCCATATTGTTTGACGGCAGAAACCTGTATTCGCCTGA
ATTTATGGCGAAGGAAGGCTTCGCCTACTTCTGCGTGGGGCGGCCCTCCGGCAAATGA

Upstream 100 bases:

>100_bases
GGGCCGCCCGCCAGGCATTGACGTTTTTGGGGGTTGTGAGTAACTGAATCGTGCAGAAAACTGATCAAGGAAGCATACTC
AACGCTATAAGGATATCATA

Downstream 100 bases:

>100_bases
TCTTCATTTGCAAAGCAGTATTGTAAAAAAAGCCCCGCTTGCGCGGGGCTTTTCTCTTTTGGTCAGAGCAGCACAATTTG
CGGTGCCGGACAAAAAATGT

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MNVCIVGTGYVGLVSAACFAEMGNTVRCVDVNPEVVETLKAGKVHIYEPGLEELVRRNYAEGRLQFTTSLEDGLKDSLFV
FITVGTPSRDDGSCDLGFVEQVARQVGAGMTDRKIVVDKSTVPVGTADKVRAIIAAELEKRGVDIPFDVVSNPEFLKEGD
AVNDFMKPDRVVVGTDSAETAEYLKQLYAPFARSREKLIVMGVRSAEMTKYAANCMLATKISFINEIATLCERVGADVRD
VRTGIGSDHRIGYHFIYPGVGYGGSCFPKDVKALIHTAREYGFRPQLLEAVEDVNYRQKKHMAERILEYFAPQGGVQGKT
IALWGLAFKANTDDMREAAALTIIQELTAQGMKVQAYDPVAADNARALLADNPLVTIVDEQYEAVEGAQALLVVTEWNQF
RNPDFGRVRKSLTAPILFDGRNLYSPEFMAKEGFAYFCVGRPSGK

Sequences:

>Translated_445_residues
MNVCIVGTGYVGLVSAACFAEMGNTVRCVDVNPEVVETLKAGKVHIYEPGLEELVRRNYAEGRLQFTTSLEDGLKDSLFV
FITVGTPSRDDGSCDLGFVEQVARQVGAGMTDRKIVVDKSTVPVGTADKVRAIIAAELEKRGVDIPFDVVSNPEFLKEGD
AVNDFMKPDRVVVGTDSAETAEYLKQLYAPFARSREKLIVMGVRSAEMTKYAANCMLATKISFINEIATLCERVGADVRD
VRTGIGSDHRIGYHFIYPGVGYGGSCFPKDVKALIHTAREYGFRPQLLEAVEDVNYRQKKHMAERILEYFAPQGGVQGKT
IALWGLAFKANTDDMREAAALTIIQELTAQGMKVQAYDPVAADNARALLADNPLVTIVDEQYEAVEGAQALLVVTEWNQF
RNPDFGRVRKSLTAPILFDGRNLYSPEFMAKEGFAYFCVGRPSGK
>Mature_445_residues
MNVCIVGTGYVGLVSAACFAEMGNTVRCVDVNPEVVETLKAGKVHIYEPGLEELVRRNYAEGRLQFTTSLEDGLKDSLFV
FITVGTPSRDDGSCDLGFVEQVARQVGAGMTDRKIVVDKSTVPVGTADKVRAIIAAELEKRGVDIPFDVVSNPEFLKEGD
AVNDFMKPDRVVVGTDSAETAEYLKQLYAPFARSREKLIVMGVRSAEMTKYAANCMLATKISFINEIATLCERVGADVRD
VRTGIGSDHRIGYHFIYPGVGYGGSCFPKDVKALIHTAREYGFRPQLLEAVEDVNYRQKKHMAERILEYFAPQGGVQGKT
IALWGLAFKANTDDMREAAALTIIQELTAQGMKVQAYDPVAADNARALLADNPLVTIVDEQYEAVEGAQALLVVTEWNQF
RNPDFGRVRKSLTAPILFDGRNLYSPEFMAKEGFAYFCVGRPSGK

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=445, Percent_Identity=36.6292134831461, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI296040438, Length=348, Percent_Identity=37.3563218390805, Blast_Score=218, Evalue=7e-57,
Organism=Homo sapiens, GI296040443, Length=292, Percent_Identity=38.3561643835616, Blast_Score=192, Evalue=5e-49,
Organism=Escherichia coli, GI1788340, Length=370, Percent_Identity=28.1081081081081, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI48994968, Length=424, Percent_Identity=28.3018867924528, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=35.2051835853132, Blast_Score=256, Evalue=2e-68,
Organism=Drosophila melanogaster, GI17136908, Length=474, Percent_Identity=35.6540084388186, Blast_Score=272, Evalue=4e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 48889; Mature: 48889

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVCIVGTGYVGLVSAACFAEMGNTVRCVDVNPEVVETLKAGKVHIYEPGLEELVRRNYA
CCEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCHHHHHHCCCC
EGRLQFTTSLEDGLKDSLFVFITVGTPSRDDGSCDLGFVEQVARQVGAGMTDRKIVVDKS
CCEEEEEECHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
TVPVGTADKVRAIIAAELEKRGVDIPFDVVSNPEFLKEGDAVNDFMKPDRVVVGTDSAET
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHCCCCHHHHCCCCEEEEECCCHHH
AEYLKQLYAPFARSREKLIVMGVRSAEMTKYAANCMLATKISFINEIATLCERVGADVRD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRTGIGSDHRIGYHFIYPGVGYGGSCFPKDVKALIHTAREYGFRPQLLEAVEDVNYRQKK
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
HMAERILEYFAPQGGVQGKTIALWGLAFKANTDDMREAAALTIIQELTAQGMKVQAYDPV
HHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCC
AADNARALLADNPLVTIVDEQYEAVEGAQALLVVTEWNQFRNPDFGRVRKSLTAPILFDG
CCCCCCEEEECCCEEEEECCHHHHHCCCEEEEEEEECHHCCCCCHHHHHHHCCCCEEECC
RNLYSPEFMAKEGFAYFCVGRPSGK
CCCCCCCHHHCCCCEEEEECCCCCC
>Mature Secondary Structure
MNVCIVGTGYVGLVSAACFAEMGNTVRCVDVNPEVVETLKAGKVHIYEPGLEELVRRNYA
CCEEEEECCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCEEEEECCCHHHHHHCCCC
EGRLQFTTSLEDGLKDSLFVFITVGTPSRDDGSCDLGFVEQVARQVGAGMTDRKIVVDKS
CCEEEEEECHHCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
TVPVGTADKVRAIIAAELEKRGVDIPFDVVSNPEFLKEGDAVNDFMKPDRVVVGTDSAET
CCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHCCCCHHHHCCCCEEEEECCCHHH
AEYLKQLYAPFARSREKLIVMGVRSAEMTKYAANCMLATKISFINEIATLCERVGADVRD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VRTGIGSDHRIGYHFIYPGVGYGGSCFPKDVKALIHTAREYGFRPQLLEAVEDVNYRQKK
HHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHH
HMAERILEYFAPQGGVQGKTIALWGLAFKANTDDMREAAALTIIQELTAQGMKVQAYDPV
HHHHHHHHHHCCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEECCCC
AADNARALLADNPLVTIVDEQYEAVEGAQALLVVTEWNQFRNPDFGRVRKSLTAPILFDG
CCCCCCEEEECCCEEEEECCHHHHHCCCEEEEEEEECHHCCCCCHHHHHHHCCCCEEECC
RNLYSPEFMAKEGFAYFCVGRPSGK
CCCCCCCHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]