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The map label for this gene is argB

Identifier: 78357058

GI number: 78357058

Start: 2057713

End: 2058600

Strand: Direct

Name: argB

Synonym: Dde_2015

Alternate gene names: 78357058

Gene position: 2057713-2058600 (Clockwise)

Preceding gene: 78357057

Following gene: 78357060

Centisome position: 55.16

GC content: 55.07

Gene sequence:

>888_bases
GTGCAGAACGATGCGTTCAAATCCAAGGTTCTCATTGAATCCCTGCCTTACTTCCGCCAGTTCAGCGGTGAAACAGTTGT
CATAAAATACGGTGGCAACGCCATGATAGACGAAAGTCTGAAGCAGGCTTTCGCTCTGAACATCGTGCTGCTCAAGTATG
TCGGGGTCAATCCTGTTGTTGTACACGGCGGAGGCCCCCAGATAGGCCGCATGCTGCAGCAGCTGAACATTCCCACAAAC
TTCCGCGAAGGCCTGCGTGTGACGGATGACGCCACCATGGACGTTGTGGAAATGGTGCTGGTCGGCAAGGTGAACAAGCA
GATCGTCAACCTGCTGAATCTGAGCGGCGCCAAGGCTGTGGGGCTTTCGGGCAAAGACGGCCAGCTGATCAGGGCCCGCC
AGATGGAAATGGTGATCAGCAAAGAGGCTCAGGCACCAGAAATCATTGATCTGGGCAAAGTGGGAGAAGTGACAGGAGTG
GAAACAAAACTGCTGCACAGCCTGCAGCGGGACGGCTTCATTCCCGTCATTGCCCCTGTGGGCGTGGACGAAAACGGAGA
GACTTACAATATCAACGCCGACCTTGTGGCCGGTGCGGTAGCCGGTGCACTGGGAGCAAAAAGGCTTCTGCTGCTCACTG
ATGTTCCTGGCATTCTGGATAAGGACGGCAGACTCATATCTTCGCTCGATACAGCCCGCACCATGCAGCTGTTTGAAGAC
GGTACACTGAAAGGCGGCATGCTGCCCAAGGTCAAGTGCTGTCTGGAAGCTCTTGAGGACGGGGTTGAAAAGGCCATGAT
CATTGACGGACGCATCGAAAACTGCGTGCTGCTTGAGCTCTTTACCGATCACGGCATCGGTACGGAGATCACCAGGGCCT
GTTCCTGA

Upstream 100 bases:

>100_bases
TAGTCATAGACAGGGAATATGTCCGGCAGCATCTTGCAGATATCACTGCAAACAGGGATCTTACCCGTTACATACTCTAA
ACCGTGATACGGAGCATACC

Downstream 100 bases:

>100_bases
TTACAACCGGCAGGCGGAACCGCCGGGTTCCGCCTGCCGGACAACATGCATGCCGGACAATCTCTTGCTAGCGGCGCAAC
AGCATCACAGCATCGTCGCC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQNDAFKSKVLIESLPYFRQFSGETVVIKYGGNAMIDESLKQAFALNIVLLKYVGVNPVVVHGGGPQIGRMLQQLNIPTN
FREGLRVTDDATMDVVEMVLVGKVNKQIVNLLNLSGAKAVGLSGKDGQLIRARQMEMVISKEAQAPEIIDLGKVGEVTGV
ETKLLHSLQRDGFIPVIAPVGVDENGETYNINADLVAGAVAGALGAKRLLLLTDVPGILDKDGRLISSLDTARTMQLFED
GTLKGGMLPKVKCCLEALEDGVEKAMIIDGRIENCVLLELFTDHGIGTEITRACS

Sequences:

>Translated_295_residues
MQNDAFKSKVLIESLPYFRQFSGETVVIKYGGNAMIDESLKQAFALNIVLLKYVGVNPVVVHGGGPQIGRMLQQLNIPTN
FREGLRVTDDATMDVVEMVLVGKVNKQIVNLLNLSGAKAVGLSGKDGQLIRARQMEMVISKEAQAPEIIDLGKVGEVTGV
ETKLLHSLQRDGFIPVIAPVGVDENGETYNINADLVAGAVAGALGAKRLLLLTDVPGILDKDGRLISSLDTARTMQLFED
GTLKGGMLPKVKCCLEALEDGVEKAMIIDGRIENCVLLELFTDHGIGTEITRACS
>Mature_295_residues
MQNDAFKSKVLIESLPYFRQFSGETVVIKYGGNAMIDESLKQAFALNIVLLKYVGVNPVVVHGGGPQIGRMLQQLNIPTN
FREGLRVTDDATMDVVEMVLVGKVNKQIVNLLNLSGAKAVGLSGKDGQLIRARQMEMVISKEAQAPEIIDLGKVGEVTGV
ETKLLHSLQRDGFIPVIAPVGVDENGETYNINADLVAGAVAGALGAKRLLLLTDVPGILDKDGRLISSLDTARTMQLFED
GTLKGGMLPKVKCCLEALEDGVEKAMIIDGRIENCVLLELFTDHGIGTEITRACS

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=33.1914893617021, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1789181, Length=282, Percent_Identity=26.241134751773, Blast_Score=94, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6320913, Length=286, Percent_Identity=27.2727272727273, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_DESDG (Q30ZT4)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388507.1
- HSSP:   Q9HTN2
- ProteinModelPortal:   Q30ZT4
- SMR:   Q30ZT4
- STRING:   Q30ZT4
- GeneID:   3757023
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_2015
- NMPDR:   fig|207559.3.peg.747
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- ProtClustDB:   PRK00942
- BioCyc:   DDES207559:DDE_2015-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31701; Mature: 31701

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNDAFKSKVLIESLPYFRQFSGETVVIKYGGNAMIDESLKQAFALNIVLLKYVGVNPVV
CCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCEEE
VHGGGPQIGRMLQQLNIPTNFREGLRVTDDATMDVVEMVLVGKVNKQIVNLLNLSGAKAV
EECCCHHHHHHHHHCCCCCCHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GLSGKDGQLIRARQMEMVISKEAQAPEIIDLGKVGEVTGVETKLLHSLQRDGFIPVIAPV
CCCCCCCCEEHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
GVDENGETYNINADLVAGAVAGALGAKRLLLLTDVPGILDKDGRLISSLDTARTMQLFED
CCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
GTLKGGMLPKVKCCLEALEDGVEKAMIIDGRIENCVLLELFTDHGIGTEITRACS
CCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCHHHHHHCC
>Mature Secondary Structure
MQNDAFKSKVLIESLPYFRQFSGETVVIKYGGNAMIDESLKQAFALNIVLLKYVGVNPVV
CCCHHHHHHHHHHHCCHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCCEEE
VHGGGPQIGRMLQQLNIPTNFREGLRVTDDATMDVVEMVLVGKVNKQIVNLLNLSGAKAV
EECCCHHHHHHHHHCCCCCCHHCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
GLSGKDGQLIRARQMEMVISKEAQAPEIIDLGKVGEVTGVETKLLHSLQRDGFIPVIAPV
CCCCCCCCEEHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEC
GVDENGETYNINADLVAGAVAGALGAKRLLLLTDVPGILDKDGRLISSLDTARTMQLFED
CCCCCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHC
GTLKGGMLPKVKCCLEALEDGVEKAMIIDGRIENCVLLELFTDHGIGTEITRACS
CCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCEEEEEEECCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA