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The map label for this gene is htrB [C]

Identifier: 78357005

GI number: 78357005

Start: 2010290

End: 2011204

Strand: Direct

Name: htrB [C]

Synonym: Dde_1962

Alternate gene names: 78357005

Gene position: 2010290-2011204 (Clockwise)

Preceding gene: 78357004

Following gene: 78357007

Centisome position: 53.89

GC content: 53.66

Gene sequence:

>915_bases
ATGTTTGATTTCGCCTCAGAAAGTGCACTCTTTATCGGTAACAGAATAGGCTTTTCCACGGTTCGCAGATGCGGAAGGGG
GCTTGGAACGCTGCTGTGGCACATTCTTCCGGACAGACGAAAGCTGGCCGTAGAATCTATACAAAAACGTCTGGGAGCCG
GCAGACGGCAAGCAGAAGCAATCGCCAGAGAAAGCTTTAAAAGCAATTGTCAGTCGTTTGCCGAAATCCTGCTCAACCCC
CGCCTGAAAGATTCTCTGCCCCCGCTGACCGACATTGACAATGCAGAGCAGCTGGCGCGCGTTCTGGCGCTGCCGCGCCC
CATAGTGGGCATTACCGCCCATCTGGGCGCATGGGAAATGCTGACCGGCTGCCTGTCCCAACACGCACACTGCGGCAAAG
AGCAGCTTGTGGTCACGCGCAGGCAAAAAAACATGTTTTTTCAAAAGGCTATTGTCGCTCTCCGCAGCGCAAACAATCTG
CGTATAGTAGATCATAGAAATGCTGCGAGGCCCGTGCTCAAGGCGCTGAAAAACAACGCCATTGCCTGCTTTCTGGCAGA
CCACAACTGCAGCGAAGCCGAGGCATTGTTCCTGCCCTTTCTCGGCAAAACCGCAGCAGTCAACAGAGGCCCTGCCATTC
TTGCTGTAAGAGCAAAAGCCCTTGTGCTACCAGCATTTATGATAAGAGCTCCAAACGGTAGATTCCGTTTTCATCACTTG
CCGCCACTGGACACCACGGAGCTTGAGGGTACAGCCGACGAGCGTGTCGAGGCCGTAACGCGTTACTATAACAGTGCCAT
AGAGTCGATGGTCAAAAAATACCCCGAACAGTGGTTCTGGATGCACAAACGCTGGAAAACCCAGCCATCCGGGTCCCGCC
GAGTCCAGATGGAGAAGAATCAGGGGACAGAATAA

Upstream 100 bases:

>100_bases
GAGCCGTATGCACCGCAGGCAACGGCTACAGACCAGAACATGCTGGCAAGTGCAGCGGCGCAACTGCAGACAAAACTCAA
CTCCCTGAAGAACCCGTACC

Downstream 100 bases:

>100_bases
ATGAATGCCGTAAAGGGATCTGCGGAGCTCTGCAGTCCCCGGCATCCATACCTCAAACAATCTGAAATTCCGGCGACGGA
GCTGTCATTCCACAATTATA

Product: acyltransferase

Products: NA

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase; Acyltransferase HtrB Family; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis-Lipid IVA Acyltransferase; Lipid A Lauroyl Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Lauroyl Transferase; Lipid A Biosynthesis Palmitoleoyl Acyltransferase; Lauroyl Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Lipid A Acyl Transferase; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MFDFASESALFIGNRIGFSTVRRCGRGLGTLLWHILPDRRKLAVESIQKRLGAGRRQAEAIARESFKSNCQSFAEILLNP
RLKDSLPPLTDIDNAEQLARVLALPRPIVGITAHLGAWEMLTGCLSQHAHCGKEQLVVTRRQKNMFFQKAIVALRSANNL
RIVDHRNAARPVLKALKNNAIACFLADHNCSEAEALFLPFLGKTAAVNRGPAILAVRAKALVLPAFMIRAPNGRFRFHHL
PPLDTTELEGTADERVEAVTRYYNSAIESMVKKYPEQWFWMHKRWKTQPSGSRRVQMEKNQGTE

Sequences:

>Translated_304_residues
MFDFASESALFIGNRIGFSTVRRCGRGLGTLLWHILPDRRKLAVESIQKRLGAGRRQAEAIARESFKSNCQSFAEILLNP
RLKDSLPPLTDIDNAEQLARVLALPRPIVGITAHLGAWEMLTGCLSQHAHCGKEQLVVTRRQKNMFFQKAIVALRSANNL
RIVDHRNAARPVLKALKNNAIACFLADHNCSEAEALFLPFLGKTAAVNRGPAILAVRAKALVLPAFMIRAPNGRFRFHHL
PPLDTTELEGTADERVEAVTRYYNSAIESMVKKYPEQWFWMHKRWKTQPSGSRRVQMEKNQGTE
>Mature_304_residues
MFDFASESALFIGNRIGFSTVRRCGRGLGTLLWHILPDRRKLAVESIQKRLGAGRRQAEAIARESFKSNCQSFAEILLNP
RLKDSLPPLTDIDNAEQLARVLALPRPIVGITAHLGAWEMLTGCLSQHAHCGKEQLVVTRRQKNMFFQKAIVALRSANNL
RIVDHRNAARPVLKALKNNAIACFLADHNCSEAEALFLPFLGKTAAVNRGPAILAVRAKALVLPAFMIRAPNGRFRFHHL
PPLDTTELEGTADERVEAVTRYYNSAIESMVKKYPEQWFWMHKRWKTQPSGSRRVQMEKNQGTE

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787292, Length=292, Percent_Identity=23.6301369863014, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.-

Molecular weight: Translated: 34231; Mature: 34231

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFASESALFIGNRIGFSTVRRCGRGLGTLLWHILPDRRKLAVESIQKRLGAGRRQAEA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
IARESFKSNCQSFAEILLNPRLKDSLPPLTDIDNAEQLARVLALPRPIVGITAHLGAWEM
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCHHHH
LTGCLSQHAHCGKEQLVVTRRQKNMFFQKAIVALRSANNLRIVDHRNAARPVLKALKNNA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCC
IACFLADHNCSEAEALFLPFLGKTAAVNRGPAILAVRAKALVLPAFMIRAPNGRFRFHHL
EEEEEECCCCCCHHHHHHHHCCCHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
PPLDTTELEGTADERVEAVTRYYNSAIESMVKKYPEQWFWMHKRWKTQPSGSRRVQMEKN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCC
QGTE
CCCC
>Mature Secondary Structure
MFDFASESALFIGNRIGFSTVRRCGRGLGTLLWHILPDRRKLAVESIQKRLGAGRRQAEA
CCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHH
IARESFKSNCQSFAEILLNPRLKDSLPPLTDIDNAEQLARVLALPRPIVGITAHLGAWEM
HHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCHHHH
LTGCLSQHAHCGKEQLVVTRRQKNMFFQKAIVALRSANNLRIVDHRNAARPVLKALKNNA
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHCCC
IACFLADHNCSEAEALFLPFLGKTAAVNRGPAILAVRAKALVLPAFMIRAPNGRFRFHHL
EEEEEECCCCCCHHHHHHHHCCCHHCCCCCCEEEEEHHHHHHHHHHHHCCCCCCEEEEEC
PPLDTTELEGTADERVEAVTRYYNSAIESMVKKYPEQWFWMHKRWKTQPSGSRRVQMEKN
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEECCC
QGTE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA