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The map label for this gene is uppP

Identifier: 78356989

GI number: 78356989

Start: 1997365

End: 1998162

Strand: Reverse

Name: uppP

Synonym: Dde_1946

Alternate gene names: 78356989

Gene position: 1998162-1997365 (Counterclockwise)

Preceding gene: 78356993

Following gene: 78356988

Centisome position: 53.57

GC content: 57.14

Gene sequence:

>798_bases
ATGACTGATCTGCTTACGGCTGCCGTGCTGGGACTTGTGGAGGGTCTGACAGAATTTTTGCCAGTATCTTCAACGGGGCA
CCTGATCATTACGGGCTACCTGCTCGAATATACCGGCCCCAAGGCGGAATCGTTTCAGGTCGCCATACAGCTTGGAGCCA
TTCTGGCCGTCGTGTTTCTTTATAAAGAACGCTTTGCCGCCCTGTTTCGCTTCGGTACCGGTCACGGGCGGTTTTCCGGA
TTGCGGGGGTGGTACCTGCTTGCTCTTACCTCTGCCCCGGCCAGCGTGCTGGGCCTTTTGACACACAGCTTTATCAAGGA
GCATCTTTTCGGGCCGGTCACTGTGGCATGGGCGCTGGCTGCAGGGGCGCTGTACATTCTGGCTGTTGAGCACAAAGGTG
AAGGAACCCGTTACGAAACGCTGGATGATGTTTCTCCCGCACTGGCTTTGGGAATAGGCATGTTCCAGTGCCTTGCGTTG
TGGCCGGGGTTCTCACGGTCGGCGGCAACCATCATGGGGGCTCTGCTGCTGGGCAGCCGGCGCCGGCTTGCTGCGGAGTA
TTCGTTTGTCGCCGCTGTACCCATCATGTTTGCCGCCACAGGGTACGATATGTACAAATCTTATTCTCTCTTCTCTCCTG
CGGACATTCCTTTCTGGGCTGTGGGGCTGCTGGTGTCTTTTGCTTCGGCATGGGCGGCGGTCAAAGGCTTTATCCATCTT
GTGGGGCGGGTCACATTCCGTCCTTTTGCCTGGTACCGGCTTGCGCTTGCCCCCGTCGTGCTTCTTTTTTGGAGCTGA

Upstream 100 bases:

>100_bases
ATCATCACCATGCTGCTTGCAACCGGTCATGGCATAGGCTATTCGCGTGCTCTGATGATGTTTTCTTCTTTATTCACCTC
TTCCGACCGGATGTTGTTTA

Downstream 100 bases:

>100_bases
CGTCGAAAAACTGCTTGCAAAGCTTGGTGTTCTTGTATAAACACTGCCTCCGTCGCAGCAATACATACGTGGCGAGGTAG
CTCAGTTGGTTAGAGCATGC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MTDLLTAAVLGLVEGLTEFLPVSSTGHLIITGYLLEYTGPKAESFQVAIQLGAILAVVFLYKERFAALFRFGTGHGRFSG
LRGWYLLALTSAPASVLGLLTHSFIKEHLFGPVTVAWALAAGALYILAVEHKGEGTRYETLDDVSPALALGIGMFQCLAL
WPGFSRSAATIMGALLLGSRRRLAAEYSFVAAVPIMFAATGYDMYKSYSLFSPADIPFWAVGLLVSFASAWAAVKGFIHL
VGRVTFRPFAWYRLALAPVVLLFWS

Sequences:

>Translated_265_residues
MTDLLTAAVLGLVEGLTEFLPVSSTGHLIITGYLLEYTGPKAESFQVAIQLGAILAVVFLYKERFAALFRFGTGHGRFSG
LRGWYLLALTSAPASVLGLLTHSFIKEHLFGPVTVAWALAAGALYILAVEHKGEGTRYETLDDVSPALALGIGMFQCLAL
WPGFSRSAATIMGALLLGSRRRLAAEYSFVAAVPIMFAATGYDMYKSYSLFSPADIPFWAVGLLVSFASAWAAVKGFIHL
VGRVTFRPFAWYRLALAPVVLLFWS
>Mature_264_residues
TDLLTAAVLGLVEGLTEFLPVSSTGHLIITGYLLEYTGPKAESFQVAIQLGAILAVVFLYKERFAALFRFGTGHGRFSGL
RGWYLLALTSAPASVLGLLTHSFIKEHLFGPVTVAWALAAGALYILAVEHKGEGTRYETLDDVSPALALGIGMFQCLALW
PGFSRSAATIMGALLLGSRRRLAAEYSFVAAVPIMFAATGYDMYKSYSLFSPADIPFWAVGLLVSFASAWAAVKGFIHLV
GRVTFRPFAWYRLALAPVVLLFWS

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=266, Percent_Identity=48.8721804511278, Blast_Score=224, Evalue=4e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_DESDG (Q310A3)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388438.1
- STRING:   Q310A3
- GeneID:   3756952
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1946
- NMPDR:   fig|207559.3.peg.1279
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   PERENVT
- ProtClustDB:   PRK00281
- BioCyc:   DDES207559:DDE_1946-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28683; Mature: 28552

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11bc3d54)-; HASH(0x1267efb0)-; HASH(0x1268c3e8)-; HASH(0x1267f184)-; HASH(0x1268d678)-; HASH(0x10267c74)-; HASH(0x1267f358)-; HASH(0xeddf1dc)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLLTAAVLGLVEGLTEFLPVSSTGHLIITGYLLEYTGPKAESFQVAIQLGAILAVVFL
CCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
YKERFAALFRFGTGHGRFSGLRGWYLLALTSAPASVLGLLTHSFIKEHLFGPVTVAWALA
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGALYILAVEHKGEGTRYETLDDVSPALALGIGMFQCLALWPGFSRSAATIMGALLLGSR
HCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
RRLAAEYSFVAAVPIMFAATGYDMYKSYSLFSPADIPFWAVGLLVSFASAWAAVKGFIHL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGRVTFRPFAWYRLALAPVVLLFWS
HHHHHCCHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TDLLTAAVLGLVEGLTEFLPVSSTGHLIITGYLLEYTGPKAESFQVAIQLGAILAVVFL
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
YKERFAALFRFGTGHGRFSGLRGWYLLALTSAPASVLGLLTHSFIKEHLFGPVTVAWALA
HHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AGALYILAVEHKGEGTRYETLDDVSPALALGIGMFQCLALWPGFSRSAATIMGALLLGSR
HCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
RRLAAEYSFVAAVPIMFAATGYDMYKSYSLFSPADIPFWAVGLLVSFASAWAAVKGFIHL
HHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VGRVTFRPFAWYRLALAPVVLLFWS
HHHHHCCHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA