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The map label for this gene is coaD

Identifier: 78356826

GI number: 78356826

Start: 1835046

End: 1835558

Strand: Direct

Name: coaD

Synonym: Dde_1783

Alternate gene names: 78356826

Gene position: 1835046-1835558 (Clockwise)

Preceding gene: 78356825

Following gene: 78356827

Centisome position: 49.19

GC content: 50.49

Gene sequence:

>513_bases
ATGGGGTCAACTGACGGAAAAATAGCCATATATCCCGGAACGTTTGATCCGCTGACTAATGGACATGCCAGCCTGATACA
ACGTGGCTGCCAGATTTTCGATCATATCGTGGTCGCAGTGGCCAATGATACACCCAAAACTCCGCTTTTCACCATTGATG
AGCGTGTCCAGATGGCTCAGGAAGCGCTGGAAGGCGTGGGCAGCATTACAGTGGAGCCTTTTTCCGGCCTGCTGGTTGAC
TATGCGGAAAGAAGAGGTGCGGGGGTCATATTGCGCGGTCTCAGGGCTGTCTCCGACTTTGAATATGAGTTTCAGCTGGC
TTTAATGAACCGCAAAATGAAACGGCATATCCAGACAGTCTTTCTGATGACCGACTATAAGTGGCTTTACATCAGTTCCA
CCATTATCAAGGCTGCGGCCAGTCTGGGCGGAGATATCAAAGGACTTGTTCCGGACAATGTCTACCGCAGACTGCGTGAA
AAATACGGCTACCCTTATCCGCTTAACGGGTAG

Upstream 100 bases:

>100_bases
TCGTGGCGGAAGCTGAGGCCGCAGTATCAGAACTGCCGGAAGTCGACAGCCGTCTTGAACTTCTGGTCAACAGAACTTAC
GGACAGACAAGGATTCTCAT

Downstream 100 bases:

>100_bases
TGCGCATGTCAGAGGCTTCCGTGATTCCTGTAGTATGTATTGTCGGCCCTACCGGCGCGGGTAAGACTGCCGCGTCACTG
CATCTTGCCGCCGTGTTCGA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MGSTDGKIAIYPGTFDPLTNGHASLIQRGCQIFDHIVVAVANDTPKTPLFTIDERVQMAQEALEGVGSITVEPFSGLLVD
YAERRGAGVILRGLRAVSDFEYEFQLALMNRKMKRHIQTVFLMTDYKWLYISSTIIKAAASLGGDIKGLVPDNVYRRLRE
KYGYPYPLNG

Sequences:

>Translated_170_residues
MGSTDGKIAIYPGTFDPLTNGHASLIQRGCQIFDHIVVAVANDTPKTPLFTIDERVQMAQEALEGVGSITVEPFSGLLVD
YAERRGAGVILRGLRAVSDFEYEFQLALMNRKMKRHIQTVFLMTDYKWLYISSTIIKAAASLGGDIKGLVPDNVYRRLRE
KYGYPYPLNG
>Mature_169_residues
GSTDGKIAIYPGTFDPLTNGHASLIQRGCQIFDHIVVAVANDTPKTPLFTIDERVQMAQEALEGVGSITVEPFSGLLVDY
AERRGAGVILRGLRAVSDFEYEFQLALMNRKMKRHIQTVFLMTDYKWLYISSTIIKAAASLGGDIKGLVPDNVYRRLREK
YGYPYPLNG

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=157, Percent_Identity=46.4968152866242, Blast_Score=167, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_DESDG (Q310R6)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388275.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q310R6
- SMR:   Q310R6
- STRING:   Q310R6
- GeneID:   3756783
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1783
- NMPDR:   fig|207559.3.peg.1596
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   DDES207559:DDE_1783-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 18933; Mature: 18802

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTDGKIAIYPGTFDPLTNGHASLIQRGCQIFDHIVVAVANDTPKTPLFTIDERVQMAQ
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHH
EALEGVGSITVEPFSGLLVDYAERRGAGVILRGLRAVSDFEYEFQLALMNRKMKRHIQTV
HHHHCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FLMTDYKWLYISSTIIKAAASLGGDIKGLVPDNVYRRLREKYGYPYPLNG
HHEECCEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
GSTDGKIAIYPGTFDPLTNGHASLIQRGCQIFDHIVVAVANDTPKTPLFTIDERVQMAQ
CCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEECCCCCCCEEEHHHHHHHHH
EALEGVGSITVEPFSGLLVDYAERRGAGVILRGLRAVSDFEYEFQLALMNRKMKRHIQTV
HHHHCCCCEEECCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FLMTDYKWLYISSTIIKAAASLGGDIKGLVPDNVYRRLREKYGYPYPLNG
HHEECCEEEEHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA