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The map label for this gene is manX [H]

Identifier: 78356819

GI number: 78356819

Start: 1829105

End: 1829566

Strand: Direct

Name: manX [H]

Synonym: Dde_1776

Alternate gene names: 78356819

Gene position: 1829105-1829566 (Clockwise)

Preceding gene: 78356818

Following gene: 78356820

Centisome position: 49.03

GC content: 53.68

Gene sequence:

>462_bases
ATGTGGGTGCGGGTTGATAATCGTCTGGTTCATGGTCAGATAATAGAAACGTGGCTGCCCTATACCGGAGCAAGGCATCT
GCTGGTTGTCAACGACGAACTGGCGGCGGATGATCTGCAGCAGCAGATTGTCTCTCTGGCAGTACCCGGGCGTGTGTCCA
TCACGTTTGTGAGAATTGATGAGTTGCAGGACATCATTATGCGGCGCGGAATAGCACTGCCGGACACGCTGGTACTTTTT
GCCAACTGTGGCGACGCGCGTCGCAGCTCTGAAAATGGTTTTGAATTTGACACACTGAATATAGGCAACCTGCATTACAG
TCCGGGCAAGCGCCAGTTGTGTCCGCACGTGGCTGTTTCCGATGACGACGAAGCATGTCTGCGCTTTTTCAAGCGCAAAG
CCGTCGCGCTGGATTTCCGGTGTGTTCCAAACGCGCCTGTTCAGGTTAAGGGGTGGTCATGA

Upstream 100 bases:

>100_bases
AGTTGCAGAATCTGGCACTGGAAGCCAAAGAGTCCGGCGGCAACGGCATCGTTGTGGCCGGCGAGGTTCTGCGCCGTAAA
GCGCGAGGCAAATAGAGTAT

Downstream 100 bases:

>100_bases
TTTTTTCTTTTCACTCCCTCATGTGGGGTCTCCCCATCGCTTTTTTTTTGCCCTCTTTTCGCTCCCGCGCTTCAGCATAA
ATATCGGATTTCTTGAGCGT

Product: PTS system transporter subunit IIB

Products: NA

Alternate protein names: EIIAB-Man; Mannose-specific phosphotransferase enzyme IIA component; EIII-Man; PTS system mannose-specific EIIA component; Mannose-specific phosphotransferase enzyme IIB component; PTS system mannose-specific EIIB component [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MWVRVDNRLVHGQIIETWLPYTGARHLLVVNDELAADDLQQQIVSLAVPGRVSITFVRIDELQDIIMRRGIALPDTLVLF
ANCGDARRSSENGFEFDTLNIGNLHYSPGKRQLCPHVAVSDDDEACLRFFKRKAVALDFRCVPNAPVQVKGWS

Sequences:

>Translated_153_residues
MWVRVDNRLVHGQIIETWLPYTGARHLLVVNDELAADDLQQQIVSLAVPGRVSITFVRIDELQDIIMRRGIALPDTLVLF
ANCGDARRSSENGFEFDTLNIGNLHYSPGKRQLCPHVAVSDDDEACLRFFKRKAVALDFRCVPNAPVQVKGWS
>Mature_153_residues
MWVRVDNRLVHGQIIETWLPYTGARHLLVVNDELAADDLQQQIVSLAVPGRVSITFVRIDELQDIIMRRGIALPDTLVLF
ANCGDARRSSENGFEFDTLNIGNLHYSPGKRQLCPHVAVSDDDEACLRFFKRKAVALDFRCVPNAPVQVKGWS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI87082217, Length=143, Percent_Identity=30.0699300699301, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1788120, Length=143, Percent_Identity=27.2727272727273, Blast_Score=78, Evalue=3e-16,
Organism=Escherichia coli, GI1789527, Length=147, Percent_Identity=36.0544217687075, Blast_Score=74, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004701
- InterPro:   IPR004720 [H]

Pfam domain/function: PF03610 EIIA-man; PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 17243; Mature: 17243

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS51101 PTS_EIIB_TYPE_4 ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVRVDNRLVHGQIIETWLPYTGARHLLVVNDELAADDLQQQIVSLAVPGRVSITFVRID
CEEEECCEEECCCCEEHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHH
ELQDIIMRRGIALPDTLVLFANCGDARRSSENGFEFDTLNIGNLHYSPGKRQLCPHVAVS
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCEEC
DDDEACLRFFKRKAVALDFRCVPNAPVQVKGWS
CCHHHHHHHHHHHHEEEEEEECCCCCEEEECCC
>Mature Secondary Structure
MWVRVDNRLVHGQIIETWLPYTGARHLLVVNDELAADDLQQQIVSLAVPGRVSITFVRID
CEEEECCEEECCCCEEHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCEEEEEEEHH
ELQDIIMRRGIALPDTLVLFANCGDARRSSENGFEFDTLNIGNLHYSPGKRQLCPHVAVS
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCEEC
DDDEACLRFFKRKAVALDFRCVPNAPVQVKGWS
CCHHHHHHHHHHHHEEEEEEECCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA