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The map label for this gene is kdsC [H]

Identifier: 78356810

GI number: 78356810

Start: 1822625

End: 1823146

Strand: Direct

Name: kdsC [H]

Synonym: Dde_1767

Alternate gene names: 78356810

Gene position: 1822625-1823146 (Clockwise)

Preceding gene: 78356809

Following gene: 78356811

Centisome position: 48.86

GC content: 59.77

Gene sequence:

>522_bases
ATGCGTGTTAAAGAGCTGGCCGCCAACATCCGCCTGCTTGTTCTGGATGTGGACGGGGTGCTGACAGACGGCGGTCTGTA
CTATTTTGGTGACGGCAGGGTGGCCAAGCGCTTCAATGTGCAGGACGGGCTGGGAATCAAGATGGCTCAGTCCGCAGGGC
TTGTCGTGGCCGTGATTACCGGTCTTGACTCTGAAGCCGTGGCCGAGCGTGTGCGCGGGCTGGGCATAGAGGACTACCAT
GCGGGCTTCACGCACAAGCTGGACGTCATGCAGGGATTGCTTGAAAAATATGCTCTCAAACCGGAGCAGGCCGCTTTTCT
GGGCGATGACTGGGTGGATCTGGCCCCGCTCAATCTTGTGGGGCTGCCCATGGCAGTGGCCAACGCCCAGCCGGAGGTAA
AGGCCGTGGCCAAATATGTCACCACCGCCACGGGAGGCCATGGCGCCGTGCGCGAAGCTGTACGTTTTATCCTTGATGCC
CAGAACAAACTGGCTCCCATGCTCAGGGAGTGGTCTTCCTAG

Upstream 100 bases:

>100_bases
CCCGACCCCGACAAGGCGCTGTGCGACGGCCCCAACAGCTGGCCCGCGGGGCGCCTGAGCGATCTTGTAGGAGATCTGAA
GAGCATCTGGAGTATTGACT

Downstream 100 bases:

>100_bases
ATGTCCCGCCGCAGAATGTACTGGGTCGCCGGTATGCTGATTCTGCTCACCGGCCTGCTGTTGTATGCGGCCATGGGGGC
ACGTCAGGTCAGTGAAGTGC

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MRVKELAANIRLLVLDVDGVLTDGGLYYFGDGRVAKRFNVQDGLGIKMAQSAGLVVAVITGLDSEAVAERVRGLGIEDYH
AGFTHKLDVMQGLLEKYALKPEQAAFLGDDWVDLAPLNLVGLPMAVANAQPEVKAVAKYVTTATGGHGAVREAVRFILDA
QNKLAPMLREWSS

Sequences:

>Translated_173_residues
MRVKELAANIRLLVLDVDGVLTDGGLYYFGDGRVAKRFNVQDGLGIKMAQSAGLVVAVITGLDSEAVAERVRGLGIEDYH
AGFTHKLDVMQGLLEKYALKPEQAAFLGDDWVDLAPLNLVGLPMAVANAQPEVKAVAKYVTTATGGHGAVREAVRFILDA
QNKLAPMLREWSS
>Mature_173_residues
MRVKELAANIRLLVLDVDGVLTDGGLYYFGDGRVAKRFNVQDGLGIKMAQSAGLVVAVITGLDSEAVAERVRGLGIEDYH
AGFTHKLDVMQGLLEKYALKPEQAAFLGDDWVDLAPLNLVGLPMAVANAQPEVKAVAKYVTTATGGHGAVREAVRFILDA
QNKLAPMLREWSS

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=156, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI2367202, Length=158, Percent_Identity=47.4683544303797, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 18592; Mature: 18592

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKELAANIRLLVLDVDGVLTDGGLYYFGDGRVAKRFNVQDGLGIKMAQSAGLVVAVIT
CCHHHHHCCEEEEEEECCCEEECCCEEEEECCCEEEEECCCCCCCEEEECCCCEEEEEEE
GLDSEAVAERVRGLGIEDYHAGFTHKLDVMQGLLEKYALKPEQAAFLGDDWVDLAPLNLV
CCCHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHH
GLPMAVANAQPEVKAVAKYVTTATGGHGAVREAVRFILDAQNKLAPMLREWSS
CCCHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MRVKELAANIRLLVLDVDGVLTDGGLYYFGDGRVAKRFNVQDGLGIKMAQSAGLVVAVIT
CCHHHHHCCEEEEEEECCCEEECCCEEEEECCCEEEEECCCCCCCEEEECCCCEEEEEEE
GLDSEAVAERVRGLGIEDYHAGFTHKLDVMQGLLEKYALKPEQAAFLGDDWVDLAPLNLV
CCCHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCHH
GLPMAVANAQPEVKAVAKYVTTATGGHGAVREAVRFILDAQNKLAPMLREWSS
CCCHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]