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The map label for this gene is mdaB [H]

Identifier: 78356661

GI number: 78356661

Start: 1667691

End: 1668290

Strand: Reverse

Name: mdaB [H]

Synonym: Dde_1618

Alternate gene names: 78356661

Gene position: 1668290-1667691 (Counterclockwise)

Preceding gene: 78356662

Following gene: 78356652

Centisome position: 44.72

GC content: 51.0

Gene sequence:

>600_bases
ATGAAAAACATTCTGATACTTAATGCACATGAATATTACAGTTTTTCTCAGGGAAAGCTGAACGGATCTCTGGTGGAAAT
CGCCCGGAGCACACTTACTGCCAACGGATATTCCGTACAGAAAACGACCATGACGGATGCCTATGACGTGGATACCGAGC
TGGAGAAACACCGTACGGCGGATGCCGTCATTGTCCAGTCGCCGGTCAACTGGATGGGCATGCCGTGGAGCTTTAAAAAA
TATATGGATCTGGTCTATACGGCGGGAACTGACGGACGGCTGTGCAACGGCGACGGCAGAACACGCAAAGACCCTGCCCG
CCAGTATGGTTCCGGCGGTACCATGACGGGTAAAAAATATCTTCTTTCCCTGACATTCAATGCTCCGGCAGACGCATTCG
ATGATCCGGCGCAGAAATTCTTTGAGGGAAAAAGCGTGGATGATCTTTTCTGGCCCATGCACCTGAATTTCCGTTTTTTC
GGCATGGAGCCACTGCCCACGTTCAGTTGTCATGATGTGGTGAAAAATCCGGAAATTCTGAACGACCTGTCACGCTACGA
AGCGCATATCAGGACGCACTTCCCCGCCATCCGCCCGTAA

Upstream 100 bases:

>100_bases
TGCCACAAAGGCCCTGCATTGACAGCAGGCAGCCGGAGCGTGCTATAATGCAATGTCATTCTGACACAAAACAGCACGCC
GTTTACGGCAGGAGCCGGCA

Downstream 100 bases:

>100_bases
CGATAAGAGCACACCGGCAGCCGCTTTTCCGCCGCTGCCGGTGTGCTCTTATCAACAGCTCCGCAAGGCCGTTTTTTTCA
GCCTGTTCCTGCGTGCCGTA

Product: flavodoxin-like fold domain-containing protein

Products: NADP; a reduced quinone; reduced acceptor [C]

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKNILILNAHEYYSFSQGKLNGSLVEIARSTLTANGYSVQKTTMTDAYDVDTELEKHRTADAVIVQSPVNWMGMPWSFKK
YMDLVYTAGTDGRLCNGDGRTRKDPARQYGSGGTMTGKKYLLSLTFNAPADAFDDPAQKFFEGKSVDDLFWPMHLNFRFF
GMEPLPTFSCHDVVKNPEILNDLSRYEAHIRTHFPAIRP

Sequences:

>Translated_199_residues
MKNILILNAHEYYSFSQGKLNGSLVEIARSTLTANGYSVQKTTMTDAYDVDTELEKHRTADAVIVQSPVNWMGMPWSFKK
YMDLVYTAGTDGRLCNGDGRTRKDPARQYGSGGTMTGKKYLLSLTFNAPADAFDDPAQKFFEGKSVDDLFWPMHLNFRFF
GMEPLPTFSCHDVVKNPEILNDLSRYEAHIRTHFPAIRP
>Mature_199_residues
MKNILILNAHEYYSFSQGKLNGSLVEIARSTLTANGYSVQKTTMTDAYDVDTELEKHRTADAVIVQSPVNWMGMPWSFKK
YMDLVYTAGTDGRLCNGDGRTRKDPARQYGSGGTMTGKKYLLSLTFNAPADAFDDPAQKFFEGKSVDDLFWPMHLNFRFF
GMEPLPTFSCHDVVKNPEILNDLSRYEAHIRTHFPAIRP

Specific function: Unknown

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To H.influenzae HI_0648 and S.pombe SPAC5H10.05c [H]

Homologues:

Organism=Escherichia coli, GI1789406, Length=197, Percent_Identity=47.7157360406091, Blast_Score=176, Evalue=8e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: NA

Molecular weight: Translated: 22549; Mature: 22549

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNILILNAHEYYSFSQGKLNGSLVEIARSTLTANGYSVQKTTMTDAYDVDTELEKHRTA
CCCEEEEECHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCC
DAVIVQSPVNWMGMPWSFKKYMDLVYTAGTDGRLCNGDGRTRKDPARQYGSGGTMTGKKY
CEEEEECCCCCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCCHHHHHCCCCCCCCCEE
LLSLTFNAPADAFDDPAQKFFEGKSVDDLFWPMHLNFRFFGMEPLPTFSCHDVVKNPEIL
EEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEEECEEEECCCCCCCCCHHHHHCCHHHH
NDLSRYEAHIRTHFPAIRP
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKNILILNAHEYYSFSQGKLNGSLVEIARSTLTANGYSVQKTTMTDAYDVDTELEKHRTA
CCCEEEEECHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHCCC
DAVIVQSPVNWMGMPWSFKKYMDLVYTAGTDGRLCNGDGRTRKDPARQYGSGGTMTGKKY
CEEEEECCCCCCCCCCCHHHHHHEEEECCCCCEEECCCCCCCCCHHHHHCCCCCCCCCEE
LLSLTFNAPADAFDDPAQKFFEGKSVDDLFWPMHLNFRFFGMEPLPTFSCHDVVKNPEIL
EEEEEECCCCCCCCCHHHHHHCCCCCCCEEEEEEECEEEECCCCCCCCCHHHHHCCHHHH
NDLSRYEAHIRTHFPAIRP
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH; a quinone; Acceptor; NADPH [C]

Specific reaction: NADPH + a quinone = NADP + a reduced quinone Acceptor + NADPH = reduced acceptor + NADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]