Click here to switch to the map view.

The map label for this gene is xerC [H]

Identifier: 78356628

GI number: 78356628

Start: 1609661

End: 1610659

Strand: Direct

Name: xerC [H]

Synonym: Dde_1585

Alternate gene names: 78356628

Gene position: 1609661-1610659 (Clockwise)

Preceding gene: 78356627

Following gene: 78356635

Centisome position: 43.15

GC content: 57.86

Gene sequence:

>999_bases
ATGTCATGGACAGGCGGCGCGCCTGATTTCAACCTGCCACCTCTGCCGGATACGGCCGAAATGTATATGGGGTATCTTGC
GCTGGAAAAGGGCTATTCTTCAGCTACAGTGCGCGGGTATGCGTGTGATCTTGCGCAGTTTGAAGATTTTTTGCAGCGGC
GGGACATGTCTCTGGATACGCCTGCGGACATAGTGCCCCGTACTATCCATGATTTTCTGGCTGACCTGCACAGGCAGCAT
GTGGGCAAGTCTTCCATGGGGCGCAAACTTTCCGCCCTGCGTGGTTTTTTCAGATATCTGGCCCGCAAGGGCTTTATACG
TTCTGTTCCTACGGAAGGTATAACAAACCCCCGGCAGGCGCAGCGCAGCCCCAGAGCGTTGAACGTGGATCAGGCGTATG
CTGTGCTGGACACCAGAACTCAGGCAGCTTCACGTGCGCAGGTGCACGTGCGGCAGGCACATAAAAGAGAGCAGCTGACA
CGCGATCTGGCTCTGGCGGAGCTGCTTTACGGTTCAGGCCTGCGCATATCAGAGGCTCTTGCCCTTGACCTGTGCCATAC
AGACCCTTCAAGCGGGCTTATAAAGGTGACGGGTAAAGGCAGCAAGGAGCGGATTGTACCTCTTTCCGATACCAGCCGGC
AGGCATTGCAGCTGTGGCTTGATGTACGCGAAACGCTGGATGTTTCCGGCGGAGCGGAACAGGCTGTTTTTCTGGGCGCG
CGCGGCGGACGCCTGAACAGGCGGCAGGCGCTGCGCATCATTGAAGACCTGTGCCGCGCGGCCGGTCTGCCACAGGCCGT
ATCTCCCCATGCTCTGCGGCATTCTTTTGCCACCCACCTGCTGGAGGCGGGTGCCGACATGCGCAGTGTGCAGGAGCTGC
TGGGCCATGAACGCCTTACCACTACACAGCGTTATACGCATCTGACGTTGCGTAAAATTGTAGAGGTATACGACAGGGCG
CACCCCGGAAGCAAAGCGGGTAAAGGCGGCTCCAAATAA

Upstream 100 bases:

>100_bases
GTTGTGATGAACACGGGCGGAAGGCTGCAGCATTATGGCGAGGTGTCTGCCATTGCCTCTGCTCTGAAGAAGAAAGCAAA
GGAAGATCCACGGAGTAATT

Downstream 100 bases:

>100_bases
CAACGCATTGTGATGCAGCGGGGGGGCTGACCAGTCTACTGCTGTTTTGCCGGGGAATTTTACGCTGCGGGCCGGCGGCT
GCAAAAAAAAGCGCCCCCTT

Product: site-specific recombinase XerD-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSWTGGAPDFNLPPLPDTAEMYMGYLALEKGYSSATVRGYACDLAQFEDFLQRRDMSLDTPADIVPRTIHDFLADLHRQH
VGKSSMGRKLSALRGFFRYLARKGFIRSVPTEGITNPRQAQRSPRALNVDQAYAVLDTRTQAASRAQVHVRQAHKREQLT
RDLALAELLYGSGLRISEALALDLCHTDPSSGLIKVTGKGSKERIVPLSDTSRQALQLWLDVRETLDVSGGAEQAVFLGA
RGGRLNRRQALRIIEDLCRAAGLPQAVSPHALRHSFATHLLEAGADMRSVQELLGHERLTTTQRYTHLTLRKIVEVYDRA
HPGSKAGKGGSK

Sequences:

>Translated_332_residues
MSWTGGAPDFNLPPLPDTAEMYMGYLALEKGYSSATVRGYACDLAQFEDFLQRRDMSLDTPADIVPRTIHDFLADLHRQH
VGKSSMGRKLSALRGFFRYLARKGFIRSVPTEGITNPRQAQRSPRALNVDQAYAVLDTRTQAASRAQVHVRQAHKREQLT
RDLALAELLYGSGLRISEALALDLCHTDPSSGLIKVTGKGSKERIVPLSDTSRQALQLWLDVRETLDVSGGAEQAVFLGA
RGGRLNRRQALRIIEDLCRAAGLPQAVSPHALRHSFATHLLEAGADMRSVQELLGHERLTTTQRYTHLTLRKIVEVYDRA
HPGSKAGKGGSK
>Mature_331_residues
SWTGGAPDFNLPPLPDTAEMYMGYLALEKGYSSATVRGYACDLAQFEDFLQRRDMSLDTPADIVPRTIHDFLADLHRQHV
GKSSMGRKLSALRGFFRYLARKGFIRSVPTEGITNPRQAQRSPRALNVDQAYAVLDTRTQAASRAQVHVRQAHKREQLTR
DLALAELLYGSGLRISEALALDLCHTDPSSGLIKVTGKGSKERIVPLSDTSRQALQLWLDVRETLDVSGGAEQAVFLGAR
GGRLNRRQALRIIEDLCRAAGLPQAVSPHALRHSFATHLLEAGADMRSVQELLGHERLTTTQRYTHLTLRKIVEVYDRAH
PGSKAGKGGSK

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=310, Percent_Identity=35.4838709677419, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789261, Length=306, Percent_Identity=32.6797385620915, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790768, Length=162, Percent_Identity=36.4197530864198, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790767, Length=161, Percent_Identity=31.6770186335404, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 36701; Mature: 36570

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWTGGAPDFNLPPLPDTAEMYMGYLALEKGYSSATVRGYACDLAQFEDFLQRRDMSLDT
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
PADIVPRTIHDFLADLHRQHVGKSSMGRKLSALRGFFRYLARKGFIRSVPTEGITNPRQA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHH
QRSPRALNVDQAYAVLDTRTQAASRAQVHVRQAHKREQLTRDLALAELLYGSGLRISEAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALDLCHTDPSSGLIKVTGKGSKERIVPLSDTSRQALQLWLDVRETLDVSGGAEQAVFLGA
HHHHHCCCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
RGGRLNRRQALRIIEDLCRAAGLPQAVSPHALRHSFATHLLEAGADMRSVQELLGHERLT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
TTQRYTHLTLRKIVEVYDRAHPGSKAGKGGSK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
SWTGGAPDFNLPPLPDTAEMYMGYLALEKGYSSATVRGYACDLAQFEDFLQRRDMSLDT
CCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
PADIVPRTIHDFLADLHRQHVGKSSMGRKLSALRGFFRYLARKGFIRSVPTEGITNPRQA
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHH
QRSPRALNVDQAYAVLDTRTQAASRAQVHVRQAHKREQLTRDLALAELLYGSGLRISEAL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
ALDLCHTDPSSGLIKVTGKGSKERIVPLSDTSRQALQLWLDVRETLDVSGGAEQAVFLGA
HHHHHCCCCCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEC
RGGRLNRRQALRIIEDLCRAAGLPQAVSPHALRHSFATHLLEAGADMRSVQELLGHERLT
CCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHH
TTQRYTHLTLRKIVEVYDRAHPGSKAGKGGSK
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA