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The map label for this gene is gpt

Identifier: 78356551

GI number: 78356551

Start: 1524536

End: 1525024

Strand: Direct

Name: gpt

Synonym: Dde_1506

Alternate gene names: 78356551

Gene position: 1524536-1525024 (Clockwise)

Preceding gene: 78356550

Following gene: 78356552

Centisome position: 40.87

GC content: 55.83

Gene sequence:

>489_bases
GTGGCAGATCCTGATCGTTACAATAAAATGTTTCCCGTTTCGTGGGAGCAGCTGCACCGCGATACCAGAGCGCTCTCATG
GAGACTCATGGAGCGGGGGCCTTTCAAGGGTATAGTGGCCATCACCCGCGGCGGTCTGGTTCCCGCTGCCATTCTGGCGC
GTGAACTTGAAGTGCGTCTGGTGGATACCATCTGTATAGCCAGTTACGACTGGAAGTCGCAGGGGGGCATTTCTGTCCTG
AAAGGGGTGGAAGGTGACGGCGAGGGCTGGCTGATAGTGGATGACCTGGTGGATACCGGAACCACGGCGCGCGCAGTGCG
CGAAATGCTGCCCAAGGCTCACTTTGCCACCGTGTATGCAAAACCTTCCGGCCGTCCGGTGGTTGATACCTATATTACCG
AAGTCAGTCAGGATACATGGATTTTGTTCCCCTGGGACTCCGAGATTCAATATGTTCAGCCTCTTGTCAACCGCAGACAA
GAAGGGTAG

Upstream 100 bases:

>100_bases
CATCATGCGGCGGGTGTTTCGCTTTGTTCCGCTGAGCGCCGGATGTGCAACCCCGCACGGCGCTGCACGTTACTACAAGC
CTGTGTGACAGGAGGAATAC

Downstream 100 bases:

>100_bases
ATAGTTTTTTTCCGGTGTGAACCGGAGTGTTTACTGGCTTGGGCGGCGTTCACGGGGAACGCTGCCCGCTATGTATATTG
GGATGGTCTGCATCATCGAG

Product: xanthine-guanine phosphoribosyltransferase

Products: NA

Alternate protein names: Xanthine-guanine phosphoribosyltransferase; XGPRT

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MADPDRYNKMFPVSWEQLHRDTRALSWRLMERGPFKGIVAITRGGLVPAAILARELEVRLVDTICIASYDWKSQGGISVL
KGVEGDGEGWLIVDDLVDTGTTARAVREMLPKAHFATVYAKPSGRPVVDTYITEVSQDTWILFPWDSEIQYVQPLVNRRQ
EG

Sequences:

>Translated_162_residues
MADPDRYNKMFPVSWEQLHRDTRALSWRLMERGPFKGIVAITRGGLVPAAILARELEVRLVDTICIASYDWKSQGGISVL
KGVEGDGEGWLIVDDLVDTGTTARAVREMLPKAHFATVYAKPSGRPVVDTYITEVSQDTWILFPWDSEIQYVQPLVNRRQ
EG
>Mature_161_residues
ADPDRYNKMFPVSWEQLHRDTRALSWRLMERGPFKGIVAITRGGLVPAAILARELEVRLVDTICIASYDWKSQGGISVLK
GVEGDGEGWLIVDDLVDTGTTARAVREMLPKAHFATVYAKPSGRPVVDTYITEVSQDTWILFPWDSEIQYVQPLVNRRQE
G

Specific function: Acts on guanine, xanthine and to a lesser extent hypoxanthine

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily

Homologues:

Organism=Escherichia coli, GI1786433, Length=151, Percent_Identity=54.3046357615894, Blast_Score=177, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XGPT_DESDG (Q311U1)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_388000.1
- ProteinModelPortal:   Q311U1
- SMR:   Q311U1
- STRING:   Q311U1
- GeneID:   3756059
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1506
- NMPDR:   fig|207559.3.peg.713
- eggNOG:   COG0503
- HOGENOM:   HBG503428
- OMA:   LVDTFIT
- ProtClustDB:   PRK09177
- BioCyc:   DDES207559:DDE_1506-MONOMER
- HAMAP:   MF_01903
- InterPro:   IPR000836

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 18276; Mature: 18145

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 98-98 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPDRYNKMFPVSWEQLHRDTRALSWRLMERGPFKGIVAITRGGLVPAAILARELEVRL
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHE
VDTICIASYDWKSQGGISVLKGVEGDGEGWLIVDDLVDTGTTARAVREMLPKAHFATVYA
EHEEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
KPSGRPVVDTYITEVSQDTWILFPWDSEIQYVQPLVNRRQEG
CCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
ADPDRYNKMFPVSWEQLHRDTRALSWRLMERGPFKGIVAITRGGLVPAAILARELEVRL
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHE
VDTICIASYDWKSQGGISVLKGVEGDGEGWLIVDDLVDTGTTARAVREMLPKAHFATVYA
EHEEEEECCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCEEEEEE
KPSGRPVVDTYITEVSQDTWILFPWDSEIQYVQPLVNRRQEG
CCCCCCHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA