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The map label for this gene is cat [H]

Identifier: 78356539

GI number: 78356539

Start: 1515122

End: 1515778

Strand: Direct

Name: cat [H]

Synonym: Dde_1494

Alternate gene names: 78356539

Gene position: 1515122-1515778 (Clockwise)

Preceding gene: 78356538

Following gene: 78356540

Centisome position: 40.62

GC content: 56.16

Gene sequence:

>657_bases
ATGACTAAAGACAGCATCTTCACCAGTCCGTTCAAGGGCATTCCCCTGCATGAGCAGGTAAGCAATCCGAACATAACAGT
CGGCCGTTACAGTTATTATTCCGGGTATTACCACAACCACCCGTTTGAAGACTGTGTCCGCTATCTTATGCCGCAACCGG
ATACCGTGGACAGGCTGATCATAGGCAGCTTCTGCTCCATCGGAACGGGCGCCAGCTTTGTCATGGCGGGCAATCAGGGG
CATCGTACCGACTGGATAAGCACTTTTCCCTTCTACTACGCAGGCAATGCCGAATTTTCCGGTGCCCGTGACGGCTACAG
GCCGGCCGGAGATACGGTGGTGGGCAGCGATGTGTGGATAGGAGCCGAAGCCATGATCATGCCGGGAGTGTGTATCGGGC
ACGGGGCTGTCATTGCTTCGCGTGCCGTGGTCACTTCTGATGTGCCTCCGTACGCCGTGGTGGCCGGCATGCCCGCCAGA
CAGCTGCGTGTCCGGTTTGATGAGAAAAGTGTGGCCATGCTGCTTGAAATGGCGTGGTGGGAGTGGCCGCAGGATATGCT
GAGTGCTGCCATGCCGCTGCTGACCTCACAAAATGTGGGTGAACTCTACCGTTTCTGGAAAAGTTATGGTAACAGGACGG
CAAACGTCACGGCATGA

Upstream 100 bases:

>100_bases
ACCCGACCTGCCGTCGCTTACTTCGCGTGCGCGTGCGCTGATCACTTCTTATTTCGGTATCTAGCTTTTGCCCGCAGTAT
GGTATAACGCTGTGGACATT

Downstream 100 bases:

>100_bases
CGCCGGGGCGCATGCGGCTGTGCGTCCTGTGGATGTGTGCCGATCACCTGCCTGAAACGTAAGGAGTTCTGATGTTCAAC
GGGCGTTTTGACTGCGACCT

Product: chloramphenicol O-acetyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MTKDSIFTSPFKGIPLHEQVSNPNITVGRYSYYSGYYHNHPFEDCVRYLMPQPDTVDRLIIGSFCSIGTGASFVMAGNQG
HRTDWISTFPFYYAGNAEFSGARDGYRPAGDTVVGSDVWIGAEAMIMPGVCIGHGAVIASRAVVTSDVPPYAVVAGMPAR
QLRVRFDEKSVAMLLEMAWWEWPQDMLSAAMPLLTSQNVGELYRFWKSYGNRTANVTA

Sequences:

>Translated_218_residues
MTKDSIFTSPFKGIPLHEQVSNPNITVGRYSYYSGYYHNHPFEDCVRYLMPQPDTVDRLIIGSFCSIGTGASFVMAGNQG
HRTDWISTFPFYYAGNAEFSGARDGYRPAGDTVVGSDVWIGAEAMIMPGVCIGHGAVIASRAVVTSDVPPYAVVAGMPAR
QLRVRFDEKSVAMLLEMAWWEWPQDMLSAAMPLLTSQNVGELYRFWKSYGNRTANVTA
>Mature_217_residues
TKDSIFTSPFKGIPLHEQVSNPNITVGRYSYYSGYYHNHPFEDCVRYLMPQPDTVDRLIIGSFCSIGTGASFVMAGNQGH
RTDWISTFPFYYAGNAEFSGARDGYRPAGDTVVGSDVWIGAEAMIMPGVCIGHGAVIASRAVVTSDVPPYAVVAGMPARQ
LRVRFDEKSVAMLLEMAWWEWPQDMLSAAMPLLTSQNVGELYRFWKSYGNRTANVTA

Specific function: This enzyme is an effector of chloramphenicol resistance in bacteria [H]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.28 [H]

Molecular weight: Translated: 24116; Mature: 23984

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDSIFTSPFKGIPLHEQVSNPNITVGRYSYYSGYYHNHPFEDCVRYLMPQPDTVDRLI
CCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHH
IGSFCSIGTGASFVMAGNQGHRTDWISTFPFYYAGNAEFSGARDGYRPAGDTVVGSDVWI
HHHHHCCCCCCEEEEECCCCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCEEECCCEEE
GAEAMIMPGVCIGHGAVIASRAVVTSDVPPYAVVAGMPARQLRVRFDEKSVAMLLEMAWW
CCCHHCCCCEEECCCHHHHHCEEEECCCCCEEEEECCCHHHEEEEECHHHHHHHHHHHHH
EWPQDMLSAAMPLLTSQNVGELYRFWKSYGNRTANVTA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCC
>Mature Secondary Structure 
TKDSIFTSPFKGIPLHEQVSNPNITVGRYSYYSGYYHNHPFEDCVRYLMPQPDTVDRLI
CCCCCCCCCCCCCCCHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHH
IGSFCSIGTGASFVMAGNQGHRTDWISTFPFYYAGNAEFSGARDGYRPAGDTVVGSDVWI
HHHHHCCCCCCEEEEECCCCCCCCCEECCCEEEECCCCCCCCCCCCCCCCCEEECCCEEE
GAEAMIMPGVCIGHGAVIASRAVVTSDVPPYAVVAGMPARQLRVRFDEKSVAMLLEMAWW
CCCHHCCCCEEECCCHHHHHCEEEECCCCCEEEEECCCHHHEEEEECHHHHHHHHHHHHH
EWPQDMLSAAMPLLTSQNVGELYRFWKSYGNRTANVTA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013403; 11743193; 11743194 [H]