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The map label for this gene is cmk

Identifier: 78356497

GI number: 78356497

Start: 1475943

End: 1476602

Strand: Reverse

Name: cmk

Synonym: Dde_1452

Alternate gene names: 78356497

Gene position: 1476602-1475943 (Counterclockwise)

Preceding gene: 78356498

Following gene: 78356496

Centisome position: 39.58

GC content: 57.12

Gene sequence:

>660_bases
GTGGCTGAACACATCATTGTCACACTGGACGGCCCCGCCGGAGTGGGTAAAACCACACTGGCCCGCAATATAGCCGAAGA
GCTGGGCATAGCGTATATGGATACCGGAGCCATGTTCCGCAGTATAGGCTGGAAACTGGGCAATGTGGTGGAATCAGTGC
CACCTGCCGAAATAGAAAAGAAACTTGCCGGATTCCGCTTTTCATTATCCGGAGCCGGGGCTGCCACGCAGCTTTCGCTC
AACGGCACACCCGTGGGGGATGAAATCCGCACCGAAGAAGTTGCCCTGCTGGCCTCTGCCGTGGCAACGCTGCCAGTGGT
CCGCACCTTTCTGAAAAAAACCCAGCAGAAACTCGGCAGTGAAGTTTCTCTGGTGGCGGAAGGACGCGACATGGGAACCG
TCATCTTTCCCGCAGCCAGATACAAATTTTTTCTGGATGCCACGCCCGAAGAACGGGCACGCCGCCGGTACGAGCAGCTC
ACGGCTGCCGGTGAGACACCGGACCTGAAGGCCCTGACGGACCAGATACGCAAACGCGACCATCAGGACCGCAGCCGGGT
GGTCGCACCGCTGCGCCCCGCAGACGACGCCATAATTATTGATACAACCGAACTGGATGTGCAGGGAGTTTTTGCAGCCA
TAATGAGCAAACTCAAATAA

Upstream 100 bases:

>100_bases
CGTCCGCTAAGCAGCTACAACCTGCCGCAGTGTCTGCGGGTCAGCATAGGCAACAGGCACGAAAACGAGCTGTTCATAGC
TCAGTTCAAGGAGCTTCTCC

Downstream 100 bases:

>100_bases
CCGGACGCACATTTTCTGTATGCCGAAACGCCTGCATCAGCAGGCGTTTTTGCTTTCAGCCTATGTTAATACCGGTTATC
TGTTGACAGAATATTGCACT

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAEHIIVTLDGPAGVGKTTLARNIAEELGIAYMDTGAMFRSIGWKLGNVVESVPPAEIEKKLAGFRFSLSGAGAATQLSL
NGTPVGDEIRTEEVALLASAVATLPVVRTFLKKTQQKLGSEVSLVAEGRDMGTVIFPAARYKFFLDATPEERARRRYEQL
TAAGETPDLKALTDQIRKRDHQDRSRVVAPLRPADDAIIIDTTELDVQGVFAAIMSKLK

Sequences:

>Translated_219_residues
MAEHIIVTLDGPAGVGKTTLARNIAEELGIAYMDTGAMFRSIGWKLGNVVESVPPAEIEKKLAGFRFSLSGAGAATQLSL
NGTPVGDEIRTEEVALLASAVATLPVVRTFLKKTQQKLGSEVSLVAEGRDMGTVIFPAARYKFFLDATPEERARRRYEQL
TAAGETPDLKALTDQIRKRDHQDRSRVVAPLRPADDAIIIDTTELDVQGVFAAIMSKLK
>Mature_218_residues
AEHIIVTLDGPAGVGKTTLARNIAEELGIAYMDTGAMFRSIGWKLGNVVESVPPAEIEKKLAGFRFSLSGAGAATQLSLN
GTPVGDEIRTEEVALLASAVATLPVVRTFLKKTQQKLGSEVSLVAEGRDMGTVIFPAARYKFFLDATPEERARRRYEQLT
AAGETPDLKALTDQIRKRDHQDRSRVVAPLRPADDAIIIDTTELDVQGVFAAIMSKLK

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=207, Percent_Identity=39.6135265700483, Blast_Score=144, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_DESDG (Q311Z5)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387946.1
- HSSP:   P0A6I0
- ProteinModelPortal:   Q311Z5
- SMR:   Q311Z5
- STRING:   Q311Z5
- GeneID:   3756083
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1452
- NMPDR:   fig|207559.3.peg.659
- eggNOG:   COG0283
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   CLSK705004
- BioCyc:   DDES207559:DDE_1452-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003959
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF00004 AAA; PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 23694; Mature: 23562

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHIIVTLDGPAGVGKTTLARNIAEELGIAYMDTGAMFRSIGWKLGNVVESVPPAEIEK
CCCEEEEEECCCCCCCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHH
KLAGFRFSLSGAGAATQLSLNGTPVGDEIRTEEVALLASAVATLPVVRTFLKKTQQKLGS
HHHCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EVSLVAEGRDMGTVIFPAARYKFFLDATPEERARRRYEQLTAAGETPDLKALTDQIRKRD
CEEEEECCCCCCEEEECHHHEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
HQDRSRVVAPLRPADDAIIIDTTELDVQGVFAAIMSKLK
CCCHHCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AEHIIVTLDGPAGVGKTTLARNIAEELGIAYMDTGAMFRSIGWKLGNVVESVPPAEIEK
CCEEEEEECCCCCCCHHHHHHHHHHHHCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHH
KLAGFRFSLSGAGAATQLSLNGTPVGDEIRTEEVALLASAVATLPVVRTFLKKTQQKLGS
HHHCCEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EVSLVAEGRDMGTVIFPAARYKFFLDATPEERARRRYEQLTAAGETPDLKALTDQIRKRD
CEEEEECCCCCCEEEECHHHEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCC
HQDRSRVVAPLRPADDAIIIDTTELDVQGVFAAIMSKLK
CCCHHCEECCCCCCCCEEEEECCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA