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The map label for this gene is aprE [H]

Identifier: 78356464

GI number: 78356464

Start: 1441886

End: 1443226

Strand: Direct

Name: aprE [H]

Synonym: Dde_1419

Alternate gene names: 78356464

Gene position: 1441886-1443226 (Clockwise)

Preceding gene: 78356463

Following gene: 78356465

Centisome position: 38.65

GC content: 54.66

Gene sequence:

>1341_bases
ATGAACAGACGCGGAACTGACGGGTACCGTCTTGAAGATATCGAATATATGAGCGAGGTTGATGCCGCCCTGCGTCGCAG
GGGGCACCCCTTTGCCTTTATGCTTTCAGCCAGCGTGGCCTTGTTGTTCGGCGTGCTGGTTATCTGGGCGCATTTTGCCG
TGCTGGATGAAGTGACCAGAGGGCTGGGACAGGTCATCCCGTCGCAGCGCGTGCAGGAAATCCAGAACCTTGAAGGGGGC
ATTCTGCAGGAGATCGCCGTTTCGGAAGGGCAGATTGTGGAAAAAGGCGATATTCTTGTACGCATTGACAATGAAGCCGC
GGCCAGTTTTTACCGCGACGCCTATTCAAAGTCACTGGAGCACAAAGCCGCCATAGCCAGACTGGAGGCTGAACTGGAAG
GCTGGCGCGAGATTGTTTTTCCCGAAGATGTCATGCAGAGCGCCCCGCTGGTTATACAGGGGCAGGCTTCCATTGCTGCG
GCAAAACGGCAGCAGCAGCAGGTGGAACTGCGCGTGCTGGAAAACCAGCGCGAACAGAAAATAAAAGAAGTGCAGGAAAT
GGTACAGCGCAGGCAGAATCTGGAAAGCAGCCTGCGTGTGGCCATGGAACAGCGTGACATTGCCCGTCCGCTGATGGAAA
AAAAGGTATACCCGCGTGTGGATTACCTGACTCTTGAGCAGAAGGTCATTTCACTGCGCGGAGAAATAGATTCGCTGGCA
CTGAATATACCGCGTGCACGGTTTGCGGCTGAAGAAGCGCGGGAACGTATACGGCAGCGCGAAGCGGAATATCGCAGCGA
GGCGCTGGAAGAGATGAACAGACGTCAGGTTGAACTGCGCTCGTTGCAGGAAACCCTGTCCGCAGGCGGCGACAGAGTCA
CCCGTACCGATGTGCGTTCTCCTGTGCGCGGTACCGTGAAAAAAATCAATATCAACACCATCGGCGGGGTGGTGAAGCCC
GGTGAATCAATCATGCAGATTGTTCCGCTGGACGATACTCTGCTGATAGAAGCCCGCATCAGGCCGCAGGATATCGCCTT
TCTGCATCCCGGGCAGAAAGCCACTGTAAAGATAACTGCATATGATTTTTCGGTGTATGGCGGTCTGGAAGGCAAGGTGG
AGCAGATAAGCGCCGATACCATTCAGGATAATGATGGCAACAGTTTTTATCTGGTCAAGCTGCGTACCAGAGCAAGCGCC
ATACAGTACAGGGGCGAGCAGTTGCCCATTATTCCGGGCATGATGGCCACGGTGGATATTCTTACGGGCAAAAAGACCGT
GCTCGATTACCTGCTTAAGCCCATTCTGAAGGCCAGACAGAACGCGCTCAGGGAGCGTTGA

Upstream 100 bases:

>100_bases
CCTCGGAACAGGTGCGCACGGCAGCCCCGGCAGGGATGGCACGCGGCGGGGCGGCGGCACGGGCATGAAGCGTACGGTCT
GACTAAACGGAGCACAGCGG

Downstream 100 bases:

>100_bases
TGGAAAACACGCGTGGCCGGGGCGTTACCGCCGCCTTTCTGCATACTGTCTGCCGCCTGACTGCGCGCGGACGGCAGAGT
ATGTGCAAACGCTGCATGCT

Product: Type I secretion membrane fusion protein, HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 446

Protein sequence:

>446_residues
MNRRGTDGYRLEDIEYMSEVDAALRRRGHPFAFMLSASVALLFGVLVIWAHFAVLDEVTRGLGQVIPSQRVQEIQNLEGG
ILQEIAVSEGQIVEKGDILVRIDNEAAASFYRDAYSKSLEHKAAIARLEAELEGWREIVFPEDVMQSAPLVIQGQASIAA
AKRQQQQVELRVLENQREQKIKEVQEMVQRRQNLESSLRVAMEQRDIARPLMEKKVYPRVDYLTLEQKVISLRGEIDSLA
LNIPRARFAAEEARERIRQREAEYRSEALEEMNRRQVELRSLQETLSAGGDRVTRTDVRSPVRGTVKKININTIGGVVKP
GESIMQIVPLDDTLLIEARIRPQDIAFLHPGQKATVKITAYDFSVYGGLEGKVEQISADTIQDNDGNSFYLVKLRTRASA
IQYRGEQLPIIPGMMATVDILTGKKTVLDYLLKPILKARQNALRER

Sequences:

>Translated_446_residues
MNRRGTDGYRLEDIEYMSEVDAALRRRGHPFAFMLSASVALLFGVLVIWAHFAVLDEVTRGLGQVIPSQRVQEIQNLEGG
ILQEIAVSEGQIVEKGDILVRIDNEAAASFYRDAYSKSLEHKAAIARLEAELEGWREIVFPEDVMQSAPLVIQGQASIAA
AKRQQQQVELRVLENQREQKIKEVQEMVQRRQNLESSLRVAMEQRDIARPLMEKKVYPRVDYLTLEQKVISLRGEIDSLA
LNIPRARFAAEEARERIRQREAEYRSEALEEMNRRQVELRSLQETLSAGGDRVTRTDVRSPVRGTVKKININTIGGVVKP
GESIMQIVPLDDTLLIEARIRPQDIAFLHPGQKATVKITAYDFSVYGGLEGKVEQISADTIQDNDGNSFYLVKLRTRASA
IQYRGEQLPIIPGMMATVDILTGKKTVLDYLLKPILKARQNALRER
>Mature_446_residues
MNRRGTDGYRLEDIEYMSEVDAALRRRGHPFAFMLSASVALLFGVLVIWAHFAVLDEVTRGLGQVIPSQRVQEIQNLEGG
ILQEIAVSEGQIVEKGDILVRIDNEAAASFYRDAYSKSLEHKAAIARLEAELEGWREIVFPEDVMQSAPLVIQGQASIAA
AKRQQQQVELRVLENQREQKIKEVQEMVQRRQNLESSLRVAMEQRDIARPLMEKKVYPRVDYLTLEQKVISLRGEIDSLA
LNIPRARFAAEEARERIRQREAEYRSEALEEMNRRQVELRSLQETLSAGGDRVTRTDVRSPVRGTVKKININTIGGVVKP
GESIMQIVPLDDTLLIEARIRPQDIAFLHPGQKATVKITAYDFSVYGGLEGKVEQISADTIQDNDGNSFYLVKLRTRASA
IQYRGEQLPIIPGMMATVDILTGKKTVLDYLLKPILKARQNALRER

Specific function: Involved in the secretion of alkaline protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 50472; Mature: 50472

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRRGTDGYRLEDIEYMSEVDAALRRRGHPFAFMLSASVALLFGVLVIWAHFAVLDEVTR
CCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGQVIPSQRVQEIQNLEGGILQEIAVSEGQIVEKGDILVRIDNEAAASFYRDAYSKSLE
HHHHHCCHHHHHHHHHCCCHHHHHHHCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHH
HKAAIARLEAELEGWREIVFPEDVMQSAPLVIQGQASIAAAKRQQQQVELRVLENQREQK
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
IKEVQEMVQRRQNLESSLRVAMEQRDIARPLMEKKVYPRVDYLTLEQKVISLRGEIDSLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHH
LNIPRARFAAEEARERIRQREAEYRSEALEEMNRRQVELRSLQETLSAGGDRVTRTDVRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCC
PVRGTVKKININTIGGVVKPGESIMQIVPLDDTLLIEARIRPQDIAFLHPGQKATVKITA
CHHCCCEEEEEECCCCCCCCCHHHEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEEEE
YDFSVYGGLEGKVEQISADTIQDNDGNSFYLVKLRTRASAIQYRGEQLPIIPGMMATVDI
EEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHCCCCCCCCCCHHHHHHH
LTGKKTVLDYLLKPILKARQNALRER
HCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRRGTDGYRLEDIEYMSEVDAALRRRGHPFAFMLSASVALLFGVLVIWAHFAVLDEVTR
CCCCCCCCCEEHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGQVIPSQRVQEIQNLEGGILQEIAVSEGQIVEKGDILVRIDNEAAASFYRDAYSKSLE
HHHHHCCHHHHHHHHHCCCHHHHHHHCCCCCEEECCCEEEEECCHHHHHHHHHHHHHHHH
HKAAIARLEAELEGWREIVFPEDVMQSAPLVIQGQASIAAAKRQQQQVELRVLENQREQK
HHHHHHHHHHHHHHHHHHCCCHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
IKEVQEMVQRRQNLESSLRVAMEQRDIARPLMEKKVYPRVDYLTLEQKVISLRGEIDSLA
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHH
LNIPRARFAAEEARERIRQREAEYRSEALEEMNRRQVELRSLQETLSAGGDRVTRTDVRS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCC
PVRGTVKKININTIGGVVKPGESIMQIVPLDDTLLIEARIRPQDIAFLHPGQKATVKITA
CHHCCCEEEEEECCCCCCCCCHHHEEEECCCCEEEEEEECCCCCEEEECCCCCEEEEEEE
YDFSVYGGLEGKVEQISADTIQDNDGNSFYLVKLRTRASAIQYRGEQLPIIPGMMATVDI
EEEEEECCCCCCHHHHCCCCCCCCCCCEEEEEEEECHHHHHHHCCCCCCCCCCHHHHHHH
LTGKKTVLDYLLKPILKARQNALRER
HCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1427098; 10984043 [H]