Click here to switch to the map view.

The map label for this gene is appB [H]

Identifier: 78356375

GI number: 78356375

Start: 1347627

End: 1348706

Strand: Reverse

Name: appB [H]

Synonym: Dde_1328

Alternate gene names: 78356375

Gene position: 1348706-1347627 (Counterclockwise)

Preceding gene: 78356376

Following gene: 78356374

Centisome position: 36.16

GC content: 61.57

Gene sequence:

>1080_bases
ATGGACATGGACGTGCGATTAAGCGCTGATAACAGACCGGCGGAAGAGCCTGCGCCGCTCCGCCGGTCTGTATTATCCTC
CGCAGCAGGCCGGCTGGCACGCTTTGCCGCTGCAAAAGCCGTCCGGCTGGCGCTGCTGCTGGTCTCTGTGGCAACCCTGT
CGTTTGTACTGGTCAGCTTTTCACCGGTCGACCCCATTGACGCCTATCTGGGGCCGTCCATTCTCAAGGTGTCTCCGGAA
CAGCGCGAGGTCATAGCACAGCGCTGGGGGCTGGACCAACCGCCGGTGGAGCGGTTCACCCGCTGGGCGGCCAATCTGCT
GCAGGGCGACTTCGGCACTTCAACCATTTTCAACGAGCCGGTACTTACCGTCATCGTCAAGCGCTTCACCACATCCTTCT
GGCTCATGTTCGCCGCCTGGACGGTGTCCGGCGTGCTCGGATTCACTCTGGGGCTGCTGGCGGGGGCCTATCCCGCAAGT
CCGCTGGACAAAACCATCAGCTTCTATGCCTACCTCATGGCGTCCACTCCCACGTTCTGGGTCGGCATGGTGCTGCTTAC
CTTTTTCTCCGTGCATCTGGGCTGGACGCCGGTACACGGGGCATGGCCCGCCGGCATGGCCGCACACGACGTCAGCCTGA
TGCAGCGCATACATCATCTCATCCTGCCGGCTGTCACGCTTTCACTCATCGGAGTGGCACAGATAGCCCTGCATACGCGT
GAAAAGACCATCGACGTCATGCGCAGCGAACACGCCCTTTTTGCCATGGCGCAGGGAGAACGCCCTCTGGGCATTGTTTT
CTGCCGCACGCTGCGCAATGTGGCCCTGCCCGCCGTAACACTGCAGTTTGCTTCACTGGGCGAACTGTTCGGGGGGGCCG
TGCTGGCAGAACAGGTCTTCGCCTATCCGGGGCTGGGCAAAGCCACAGTGGAAGCCGGATTCAGGGGGGATGTGCCCCTG
CTGCTGGGGCTGGTCATTTTCAGCACGGTATTTGTCTTTACCGGCAACACGGTGGCCGACCTGCTGTATATGATCGTAGA
CCCGCGCATGCGGCGCAATGCCCGCAAAGGAGACCGGTAA

Upstream 100 bases:

>100_bases
ACCTCGATCACACCTACTTTGTCAACAAATGCCTCGATGTGGGTACATCGCAGATGGAACCCCACGGTCACGGCTGGCCC
ATCACAGCCAACATTGTTGA

Downstream 100 bases:

>100_bases
CATGGCGGCACTGGCCACAGACAGACGAACCCGCACCATAATGACCATTGCCGCCTGCACCGCCCTGTTTGCCGCGGTGT
TTGCGGGTGCATGGCTGTAC

Product: dipeptide ABC transporter permease

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MDMDVRLSADNRPAEEPAPLRRSVLSSAAGRLARFAAAKAVRLALLLVSVATLSFVLVSFSPVDPIDAYLGPSILKVSPE
QREVIAQRWGLDQPPVERFTRWAANLLQGDFGTSTIFNEPVLTVIVKRFTTSFWLMFAAWTVSGVLGFTLGLLAGAYPAS
PLDKTISFYAYLMASTPTFWVGMVLLTFFSVHLGWTPVHGAWPAGMAAHDVSLMQRIHHLILPAVTLSLIGVAQIALHTR
EKTIDVMRSEHALFAMAQGERPLGIVFCRTLRNVALPAVTLQFASLGELFGGAVLAEQVFAYPGLGKATVEAGFRGDVPL
LLGLVIFSTVFVFTGNTVADLLYMIVDPRMRRNARKGDR

Sequences:

>Translated_359_residues
MDMDVRLSADNRPAEEPAPLRRSVLSSAAGRLARFAAAKAVRLALLLVSVATLSFVLVSFSPVDPIDAYLGPSILKVSPE
QREVIAQRWGLDQPPVERFTRWAANLLQGDFGTSTIFNEPVLTVIVKRFTTSFWLMFAAWTVSGVLGFTLGLLAGAYPAS
PLDKTISFYAYLMASTPTFWVGMVLLTFFSVHLGWTPVHGAWPAGMAAHDVSLMQRIHHLILPAVTLSLIGVAQIALHTR
EKTIDVMRSEHALFAMAQGERPLGIVFCRTLRNVALPAVTLQFASLGELFGGAVLAEQVFAYPGLGKATVEAGFRGDVPL
LLGLVIFSTVFVFTGNTVADLLYMIVDPRMRRNARKGDR
>Mature_359_residues
MDMDVRLSADNRPAEEPAPLRRSVLSSAAGRLARFAAAKAVRLALLLVSVATLSFVLVSFSPVDPIDAYLGPSILKVSPE
QREVIAQRWGLDQPPVERFTRWAANLLQGDFGTSTIFNEPVLTVIVKRFTTSFWLMFAAWTVSGVLGFTLGLLAGAYPAS
PLDKTISFYAYLMASTPTFWVGMVLLTFFSVHLGWTPVHGAWPAGMAAHDVSLMQRIHHLILPAVTLSLIGVAQIALHTR
EKTIDVMRSEHALFAMAQGERPLGIVFCRTLRNVALPAVTLQFASLGELFGGAVLAEQVFAYPGLGKATVEAGFRGDVPL
LLGLVIFSTVFVFTGNTVADLLYMIVDPRMRRNARKGDR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=333, Percent_Identity=29.7297297297297, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787053, Length=306, Percent_Identity=32.0261437908497, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1789888, Length=322, Percent_Identity=29.1925465838509, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1787761, Length=330, Percent_Identity=30.3030303030303, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787497, Length=301, Percent_Identity=27.2425249169435, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787550, Length=273, Percent_Identity=27.1062271062271, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788504, Length=288, Percent_Identity=26.0416666666667, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39128; Mature: 39128

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMDVRLSADNRPAEEPAPLRRSVLSSAAGRLARFAAAKAVRLALLLVSVATLSFVLVSF
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPVDPIDAYLGPSILKVSPEQREVIAQRWGLDQPPVERFTRWAANLLQGDFGTSTIFNEP
CCCCHHHHHHCCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCH
VLTVIVKRFTTSFWLMFAAWTVSGVLGFTLGLLAGAYPASPLDKTISFYAYLMASTPTFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHH
VGMVLLTFFSVHLGWTPVHGAWPAGMAAHDVSLMQRIHHLILPAVTLSLIGVAQIALHTR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTIDVMRSEHALFAMAQGERPLGIVFCRTLRNVALPAVTLQFASLGELFGGAVLAEQVF
HHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYPGLGKATVEAGFRGDVPLLLGLVIFSTVFVFTGNTVADLLYMIVDPRMRRNARKGDR
HCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCC
>Mature Secondary Structure
MDMDVRLSADNRPAEEPAPLRRSVLSSAAGRLARFAAAKAVRLALLLVSVATLSFVLVSF
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SPVDPIDAYLGPSILKVSPEQREVIAQRWGLDQPPVERFTRWAANLLQGDFGTSTIFNEP
CCCCHHHHHHCCCCEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHCCCH
VLTVIVKRFTTSFWLMFAAWTVSGVLGFTLGLLAGAYPASPLDKTISFYAYLMASTPTFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHH
VGMVLLTFFSVHLGWTPVHGAWPAGMAAHDVSLMQRIHHLILPAVTLSLIGVAQIALHTR
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKTIDVMRSEHALFAMAQGERPLGIVFCRTLRNVALPAVTLQFASLGELFGGAVLAEQVF
HHHHHHHHHCHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYPGLGKATVEAGFRGDVPLLLGLVIFSTVFVFTGNTVADLLYMIVDPRMRRNARKGDR
HCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]