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The map label for this gene is dsbD [H]

Identifier: 78356348

GI number: 78356348

Start: 1319763

End: 1321682

Strand: Reverse

Name: dsbD [H]

Synonym: Dde_1301

Alternate gene names: 78356348

Gene position: 1321682-1319763 (Counterclockwise)

Preceding gene: 78356349

Following gene: 78356341

Centisome position: 35.43

GC content: 58.8

Gene sequence:

>1920_bases
GTGTGCCTGTCCATGAAGACACTTCGTATATCTTTTTTCTCTTGTCTTTTCACTTTACTCTGTCTGCTGCCGGCCTTTCT
GGCCGCCCGGGCCGTTGAGCTGCCTCCTGCTGCATCCTCTGCCGCAGGCACGCCGGACACACCGGACCCGCTGGTAACCG
CTAGTCAGGCATTTTCTGTCAGCATAAACGGCCCTGCGCGTCGTGTGGCTGTTATCACCCTGACCCCCGCCGCCGGCTAC
CATTTTTATGCCCGCGAGGCAGGAGAAGCCGGCAAACCGGTCGCCATCATCGCGCTGGCAGGTGATGAGGAAAGGCCGGT
ACTATACCCGCAAGGCACCCCGAAACCGGACGCATTTGATCCTTCCCTCACCGTAAACGTGCATGACGGGCCGGCACGTT
TTTATGTGCCGCTGCCCGATGACCCCGCGGTACAGACGCTCTCATGGAGTGTTTCGGCCCTTATGTGCTCGGCTGCGAAC
TGCTGGCCGGTCTCGCGCGAAGGCACTACGGAACTGGCCGGCCAGCTGCAACGCGCAGAAGCACAGCCGTGGTGGGGCGA
ATACGCCCGGCTGGAACAGACTTCACGCCCCCCTTCAGCCGTCCGGCGCATTGATGCCGGTATGGCGGCTGTAAAACAAC
ACCCCGCTGACGGAAATGAAGTACGGCTCAGCTGGAACTTCACCCCGCGATTTTTCATGGAATCACTGGAAGTGCGCTCC
ATGGGAAAGGCCCTGCTTTTCGGCCTGATTGCAGGCCTTATACTTAACTTCATGCCGTGCGTGCTGCCTGTGGTCAGTCT
CAAGCTGTCCACCCTGCTCACCGCCAGCGGCATTCAGGACCAGAATAAACGCATACACCATTTCAGAATGCATAATATCT
GGTTTTCCGCCGGCATCATGTGCTTTTTCCTGTTGCTTGCCGCAGTTCTGGGGCTGGCCGGACTGGCCTGGGGCAGCGCG
TTCCAGAGCCAGACTCTTGTTGCCGTTCTTGTGGTTCTGGTATTTACGCTGGGTCTGAGCATGTTCGGGGTATTTAACCT
GCCGGTGCTCGACCTGAAAGCCGTCCCCGCAGAAGCGCAAAGCTCCCCGCGCGGGCAGGCATTTTTTACGGGCATGATGG
CTACCCTGCTTGCCACTCCCTGCTCGGGCCCTTTTCTGGGCGGCGTGCTGGGCTGGGCGTTCATGCAGTCTCCGCTGGTG
CTGGGGGCCGTATTCGCCAGCGTCGGACTGGGCATGTCTTCACCGTATCTCACCATGGCGGTGTTTCCCGCACTGGTAAA
GCACTTTCCCCGACCGGGCAGCTGGATAGGTATACTCGAACGCCTCGTCGGCTTTTTCCTCATGGGAACAACCGTTTACC
TGCTGCGTATTCTTCCTGAAACCCTCTGGCCGTCGATGCTGGTATTGCTGTGGATCACCGGCCTTGCCGCGTGGGTGTGG
GGTCGTTTTTCCGGGCTTGAAAAATCATTCCGCCAACGCCTCTGTGTGCGAGTGCTGTGTGCAGCGACTGTGATGGCTGC
GGCATGGTGGCTCAATCAGCCGCCTGCTCCACACCCGGGGTGGGAACGCTTCGAGGCTGCCCGCTTTGAACAGATGCTTG
GCAAGCAGCCTGTCATTGTTGACTTTACCGCCGACTGGTGCCCCAACTGCAAAGTGCTGGAGCATACCACGCTACACGCC
GAAAACCTGCGTCGCTGGATGAAGCAGTACAATGCACGCATCGTGCAGGTCGATCTTACAGAACCGTCTGTTCAGGGTGA
ATCGCTGCTCAAATCACTGGGCAGCAGTTCCATCCCCGTTGTGGCTCTTTTCCCTGCCGGACAACATTCGGACAAGCCGC
TCGTGTTGCGCGATATATTCACAACAGAGCAAATGGAGGAGGCTCTGCAGCAGGCATTCGGCCTGCCTGCGACAGAATAG

Upstream 100 bases:

>100_bases
AATTGAGCTAATGACCCGCTCTTGCGTCAAGCGCGGAGTGTGATTTAAGTGGATCGGGCCGTGATGTCAAGCGGCTTTTC
GTTTCTTCATAAAAAAAGTA

Downstream 100 bases:

>100_bases
CCGCACCCCAAAAAAATGGAAAAATAGTATTGACAACCTGTGGAGTTCTGCATAGTTTGCACTCCGCGCTTGACGCAAGA
GCGGGTCATTAGCTCAATTG

Product: Thiol:disulfide interchange protein-like

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 639; Mature: 639

Protein sequence:

>639_residues
MCLSMKTLRISFFSCLFTLLCLLPAFLAARAVELPPAASSAAGTPDTPDPLVTASQAFSVSINGPARRVAVITLTPAAGY
HFYAREAGEAGKPVAIIALAGDEERPVLYPQGTPKPDAFDPSLTVNVHDGPARFYVPLPDDPAVQTLSWSVSALMCSAAN
CWPVSREGTTELAGQLQRAEAQPWWGEYARLEQTSRPPSAVRRIDAGMAAVKQHPADGNEVRLSWNFTPRFFMESLEVRS
MGKALLFGLIAGLILNFMPCVLPVVSLKLSTLLTASGIQDQNKRIHHFRMHNIWFSAGIMCFFLLLAAVLGLAGLAWGSA
FQSQTLVAVLVVLVFTLGLSMFGVFNLPVLDLKAVPAEAQSSPRGQAFFTGMMATLLATPCSGPFLGGVLGWAFMQSPLV
LGAVFASVGLGMSSPYLTMAVFPALVKHFPRPGSWIGILERLVGFFLMGTTVYLLRILPETLWPSMLVLLWITGLAAWVW
GRFSGLEKSFRQRLCVRVLCAATVMAAAWWLNQPPAPHPGWERFEAARFEQMLGKQPVIVDFTADWCPNCKVLEHTTLHA
ENLRRWMKQYNARIVQVDLTEPSVQGESLLKSLGSSSIPVVALFPAGQHSDKPLVLRDIFTTEQMEEALQQAFGLPATE

Sequences:

>Translated_639_residues
MCLSMKTLRISFFSCLFTLLCLLPAFLAARAVELPPAASSAAGTPDTPDPLVTASQAFSVSINGPARRVAVITLTPAAGY
HFYAREAGEAGKPVAIIALAGDEERPVLYPQGTPKPDAFDPSLTVNVHDGPARFYVPLPDDPAVQTLSWSVSALMCSAAN
CWPVSREGTTELAGQLQRAEAQPWWGEYARLEQTSRPPSAVRRIDAGMAAVKQHPADGNEVRLSWNFTPRFFMESLEVRS
MGKALLFGLIAGLILNFMPCVLPVVSLKLSTLLTASGIQDQNKRIHHFRMHNIWFSAGIMCFFLLLAAVLGLAGLAWGSA
FQSQTLVAVLVVLVFTLGLSMFGVFNLPVLDLKAVPAEAQSSPRGQAFFTGMMATLLATPCSGPFLGGVLGWAFMQSPLV
LGAVFASVGLGMSSPYLTMAVFPALVKHFPRPGSWIGILERLVGFFLMGTTVYLLRILPETLWPSMLVLLWITGLAAWVW
GRFSGLEKSFRQRLCVRVLCAATVMAAAWWLNQPPAPHPGWERFEAARFEQMLGKQPVIVDFTADWCPNCKVLEHTTLHA
ENLRRWMKQYNARIVQVDLTEPSVQGESLLKSLGSSSIPVVALFPAGQHSDKPLVLRDIFTTEQMEEALQQAFGLPATE
>Mature_639_residues
MCLSMKTLRISFFSCLFTLLCLLPAFLAARAVELPPAASSAAGTPDTPDPLVTASQAFSVSINGPARRVAVITLTPAAGY
HFYAREAGEAGKPVAIIALAGDEERPVLYPQGTPKPDAFDPSLTVNVHDGPARFYVPLPDDPAVQTLSWSVSALMCSAAN
CWPVSREGTTELAGQLQRAEAQPWWGEYARLEQTSRPPSAVRRIDAGMAAVKQHPADGNEVRLSWNFTPRFFMESLEVRS
MGKALLFGLIAGLILNFMPCVLPVVSLKLSTLLTASGIQDQNKRIHHFRMHNIWFSAGIMCFFLLLAAVLGLAGLAWGSA
FQSQTLVAVLVVLVFTLGLSMFGVFNLPVLDLKAVPAEAQSSPRGQAFFTGMMATLLATPCSGPFLGGVLGWAFMQSPLV
LGAVFASVGLGMSSPYLTMAVFPALVKHFPRPGSWIGILERLVGFFLMGTTVYLLRILPETLWPSMLVLLWITGLAAWVW
GRFSGLEKSFRQRLCVRVLCAATVMAAAWWLNQPPAPHPGWERFEAARFEQMLGKQPVIVDFTADWCPNCKVLEHTTLHA
ENLRRWMKQYNARIVQVDLTEPSVQGESLLKSLGSSSIPVVALFPAGQHSDKPLVLRDIFTTEQMEEALQQAFGLPATE

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=390, Percent_Identity=24.6153846153846, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 69643; Mature: 69643

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLSMKTLRISFFSCLFTLLCLLPAFLAARAVELPPAASSAAGTPDTPDPLVTASQAFSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCEEEE
SINGPARRVAVITLTPAAGYHFYAREAGEAGKPVAIIALAGDEERPVLYPQGTPKPDAFD
EECCCCEEEEEEEEECCCCCCHHHHHCCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCC
PSLTVNVHDGPARFYVPLPDDPAVQTLSWSVSALMCSAANCWPVSREGTTELAGQLQRAE
CEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
AQPWWGEYARLEQTSRPPSAVRRIDAGMAAVKQHPADGNEVRLSWNFTPRFFMESLEVRS
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
MGKALLFGLIAGLILNFMPCVLPVVSLKLSTLLTASGIQDQNKRIHHFRMHNIWFSAGIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CFFLLLAAVLGLAGLAWGSAFQSQTLVAVLVVLVFTLGLSMFGVFNLPVLDLKAVPAEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
SSPRGQAFFTGMMATLLATPCSGPFLGGVLGWAFMQSPLVLGAVFASVGLGMSSPYLTMA
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHH
VFPALVKHFPRPGSWIGILERLVGFFLMGTTVYLLRILPETLWPSMLVLLWITGLAAWVW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRFSGLEKSFRQRLCVRVLCAATVMAAAWWLNQPPAPHPGWERFEAARFEQMLGKQPVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
DFTADWCPNCKVLEHTTLHAENLRRWMKQYNARIVQVDLTEPSVQGESLLKSLGSSSIPV
EECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCCCCCE
VALFPAGQHSDKPLVLRDIFTTEQMEEALQQAFGLPATE
EEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MCLSMKTLRISFFSCLFTLLCLLPAFLAARAVELPPAASSAAGTPDTPDPLVTASQAFSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCEEEE
SINGPARRVAVITLTPAAGYHFYAREAGEAGKPVAIIALAGDEERPVLYPQGTPKPDAFD
EECCCCEEEEEEEEECCCCCCHHHHHCCCCCCCEEEEEEECCCCCCEECCCCCCCCCCCC
PSLTVNVHDGPARFYVPLPDDPAVQTLSWSVSALMCSAANCWPVSREGTTELAGQLQRAE
CEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHC
AQPWWGEYARLEQTSRPPSAVRRIDAGMAAVKQHPADGNEVRLSWNFTPRFFMESLEVRS
CCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHH
MGKALLFGLIAGLILNFMPCVLPVVSLKLSTLLTASGIQDQNKRIHHFRMHNIWFSAGIM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
CFFLLLAAVLGLAGLAWGSAFQSQTLVAVLVVLVFTLGLSMFGVFNLPVLDLKAVPAEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
SSPRGQAFFTGMMATLLATPCSGPFLGGVLGWAFMQSPLVLGAVFASVGLGMSSPYLTMA
CCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHH
VFPALVKHFPRPGSWIGILERLVGFFLMGTTVYLLRILPETLWPSMLVLLWITGLAAWVW
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRFSGLEKSFRQRLCVRVLCAATVMAAAWWLNQPPAPHPGWERFEAARFEQMLGKQPVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEE
DFTADWCPNCKVLEHTTLHAENLRRWMKQYNARIVQVDLTEPSVQGESLLKSLGSSSIPV
EECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCCCCCE
VALFPAGQHSDKPLVLRDIFTTEQMEEALQQAFGLPATE
EEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]