Click here to switch to the map view.

The map label for this gene is cqsS [H]

Identifier: 78356332

GI number: 78356332

Start: 1302692

End: 1303081

Strand: Reverse

Name: cqsS [H]

Synonym: Dde_1285

Alternate gene names: 78356332

Gene position: 1303081-1302692 (Counterclockwise)

Preceding gene: 78356333

Following gene: 78356331

Centisome position: 34.93

GC content: 57.44

Gene sequence:

>390_bases
ATGACAAGGCGCAGCCCCCGATATAGCGGACGCCGCATTCTGGTTGTAGAAGACAACCGCGTCAGCCGGACCATGCTTGA
GCTTATGCTGACCAAAGCCGGTTATGAAACGGAATGTGTTGCCGACGGTGATGCCGCGCTTGCCGGTATGAGCGGCAGAC
ATTTTGATCTGTTGCTGCTGGATATAGAGCTGCCGGACATAACCGGAGACAGACTGCTGCCCCGCCTGCGCGCCTGCCGT
CCGGAAGAAGCATCTGTGCCTGCTGTGGCTGTTACGGCCCATCACGACAGCGACATCCGCCGTCAACTGACCGCAGCCGG
TTTCACCGCCGTGTTCAGCAAACCGCTGGATATGCCGCAGCTGATTGATGCTATTGAAAAACTGCTGTAA

Upstream 100 bases:

>100_bases
AACTGGAAAGCGCCACCGTCCGCAACCGCAAGGCGATGGAAGACTTGTTCCGCATGCAGACAGTGCTGCGGCAGAACGGA
AAACAGGGGACAGGACAGCC

Downstream 100 bases:

>100_bases
CACATGCAAAAAAACAAGAAATGCACAACATACTTTCAGCAGCGCAAGCCCATACAGCATTGATTAATCAGACAAAATCA
TGCGCAGCACGGGCACGCCG

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: Cholerae quorum-sensing sensor [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MTRRSPRYSGRRILVVEDNRVSRTMLELMLTKAGYETECVADGDAALAGMSGRHFDLLLLDIELPDITGDRLLPRLRACR
PEEASVPAVAVTAHHDSDIRRQLTAAGFTAVFSKPLDMPQLIDAIEKLL

Sequences:

>Translated_129_residues
MTRRSPRYSGRRILVVEDNRVSRTMLELMLTKAGYETECVADGDAALAGMSGRHFDLLLLDIELPDITGDRLLPRLRACR
PEEASVPAVAVTAHHDSDIRRQLTAAGFTAVFSKPLDMPQLIDAIEKLL
>Mature_128_residues
TRRSPRYSGRRILVVEDNRVSRTMLELMLTKAGYETECVADGDAALAGMSGRHFDLLLLDIELPDITGDRLLPRLRACRP
EEASVPAVAVTAHHDSDIRRQLTAAGFTAVFSKPLDMPQLIDAIEKLL

Specific function: Senses the quorum-sensing autoinducer CAI-1 ((S)-3- hydroxytridecan-4-one) which probably functions as an intragenus signal. The sensory signal is then relayed to luxU and luxO [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=118, Percent_Identity=35.5932203389831, Blast_Score=61, Evalue=2e-11,
Organism=Escherichia coli, GI145693157, Length=117, Percent_Identity=30.7692307692308, Blast_Score=60, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 14302; Mature: 14171

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRSPRYSGRRILVVEDNRVSRTMLELMLTKAGYETECVADGDAALAGMSGRHFDLLLL
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEEEE
DIELPDITGDRLLPRLRACRPEEASVPAVAVTAHHDSDIRRQLTAAGFTAVFSKPLDMPQ
EEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHH
LIDAIEKLL
HHHHHHHHC
>Mature Secondary Structure 
TRRSPRYSGRRILVVEDNRVSRTMLELMLTKAGYETECVADGDAALAGMSGRHFDLLLL
CCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCEEECCCCCCEEEEEE
DIELPDITGDRLLPRLRACRPEEASVPAVAVTAHHDSDIRRQLTAAGFTAVFSKPLDMPQ
EEECCCCCCHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHH
LIDAIEKLL
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]