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The map label for this gene is yrbG [H]

Identifier: 78356235

GI number: 78356235

Start: 1217398

End: 1218375

Strand: Direct

Name: yrbG [H]

Synonym: Dde_1188

Alternate gene names: 78356235

Gene position: 1217398-1218375 (Clockwise)

Preceding gene: 78356227

Following gene: 78356236

Centisome position: 32.64

GC content: 61.25

Gene sequence:

>978_bases
ATGATGACGCTTCCTATTCTTGCTATTGTGGCAGGTCTTGTGCTGCTTGTGTACAGCGCAGACCGTTTTGTGCTGGGGTC
TTCCGCCACGGCACGGCATTTCGGCATGCCTCCGCTGCTTATCGGCATGGTCATTGTGGGCTTCGGCACTTCCGTGCCTG
AAATGCTTGTTTCACTTATGGCCGCCATGAGCGGAACCCCCGGCATCGCGCTGGGCAACGCTTACGGCTCCAATATAACC
AACATAGGTCTCATACTGGGCGCCACTGCCGTTCTGGGACCTGTGATGGTCAGCTCTCAGGTGCTCCGTAAGGAGCTGCC
CATTCTTATCGGGGTGACACTGCTTACCGCCGCACTGTTGTGGGACGGCTCGCTGGACAGGACCAATGCTCTGGTGCTGC
TCGCCGTGTTTTTTGTTCTTGTGGGCTGGTCTGTTTATCAGGGCATGCATTCCACGCGCGACGCATTCGGGCAGGAGATG
GAACAGCAGGCCGGTACGCAGCCGCTGGCGCTCAAGGCCGCACTGGGCTGGACAGCCGCCGGACTGGTGTTGCTCATTAT
CAGCTCGCGCATGCTTGTGTGGGGTGCCATGAAAGTAGCCGTGGCGCTGGGCATGAGCGATCTGGTCATAGGGCTGACCA
TTGTGGCTGTGGGCACTTCGCTGCCCGAGCTGGCTTCTTCGCTGGCTGCCGCCCGTCGCGGAGAGCACGACATAGCGCTG
GGCAACGTTGTGGGCTCCAACCTGTTCAACACACTGGCTGTTGTGGGCATAGCCGGAGCGGTGCAGCCCATGCAGGTGGA
CCCGTCCGCCCTGGGACGCGATCTGCTGGTCATGGGCGGCTTTACCGTGGCGCTTTTTGTCATGGGATACCCCGTGCGCC
GCGCGGGCCGCATCAACAGGCTGGAAGGGGCCGCACTGCTGTGCGCATATGCTGCGTACACTGTCTGGCTGGTGGGCGTG
GCAGGCCAAAGCGCCTGA

Upstream 100 bases:

>100_bases
GCAGGCCGCTGCCGGAAGAGGCGGACGGGCATCCGCCTGCTTCAAGCGGGCCGGCGTTTCCGGCATGATTCAACATCAGC
GCGGGTGATCCGCAGAGGTA

Downstream 100 bases:

>100_bases
CAGCCATACCGGATATACAAAAAAAAGAGAGGAGCTCCGGCTCCTTTCTTTTTTTTGTAATGTGTCCGACATGATGCGCT
GTCCCCGTTGACAGTATTAC

Product: K+-dependent Na+/Ca+ exchanger-like protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MMTLPILAIVAGLVLLVYSADRFVLGSSATARHFGMPPLLIGMVIVGFGTSVPEMLVSLMAAMSGTPGIALGNAYGSNIT
NIGLILGATAVLGPVMVSSQVLRKELPILIGVTLLTAALLWDGSLDRTNALVLLAVFFVLVGWSVYQGMHSTRDAFGQEM
EQQAGTQPLALKAALGWTAAGLVLLIISSRMLVWGAMKVAVALGMSDLVIGLTIVAVGTSLPELASSLAAARRGEHDIAL
GNVVGSNLFNTLAVVGIAGAVQPMQVDPSALGRDLLVMGGFTVALFVMGYPVRRAGRINRLEGAALLCAYAAYTVWLVGV
AGQSA

Sequences:

>Translated_325_residues
MMTLPILAIVAGLVLLVYSADRFVLGSSATARHFGMPPLLIGMVIVGFGTSVPEMLVSLMAAMSGTPGIALGNAYGSNIT
NIGLILGATAVLGPVMVSSQVLRKELPILIGVTLLTAALLWDGSLDRTNALVLLAVFFVLVGWSVYQGMHSTRDAFGQEM
EQQAGTQPLALKAALGWTAAGLVLLIISSRMLVWGAMKVAVALGMSDLVIGLTIVAVGTSLPELASSLAAARRGEHDIAL
GNVVGSNLFNTLAVVGIAGAVQPMQVDPSALGRDLLVMGGFTVALFVMGYPVRRAGRINRLEGAALLCAYAAYTVWLVGV
AGQSA
>Mature_325_residues
MMTLPILAIVAGLVLLVYSADRFVLGSSATARHFGMPPLLIGMVIVGFGTSVPEMLVSLMAAMSGTPGIALGNAYGSNIT
NIGLILGATAVLGPVMVSSQVLRKELPILIGVTLLTAALLWDGSLDRTNALVLLAVFFVLVGWSVYQGMHSTRDAFGQEM
EQQAGTQPLALKAALGWTAAGLVLLIISSRMLVWGAMKVAVALGMSDLVIGLTIVAVGTSLPELASSLAAARRGEHDIAL
GNVVGSNLFNTLAVVGIAGAVQPMQVDPSALGRDLLVMGGFTVALFVMGYPVRRAGRINRLEGAALLCAYAAYTVWLVGV
AGQSA

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI31563526, Length=79, Percent_Identity=40.5063291139241, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1789587, Length=263, Percent_Identity=40.6844106463878, Blast_Score=178, Evalue=4e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 33529; Mature: 33529

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLPILAIVAGLVLLVYSADRFVLGSSATARHFGMPPLLIGMVIVGFGTSVPEMLVSLM
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
AAMSGTPGIALGNAYGSNITNIGLILGATAVLGPVMVSSQVLRKELPILIGVTLLTAALL
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WDGSLDRTNALVLLAVFFVLVGWSVYQGMHSTRDAFGQEMEQQAGTQPLALKAALGWTAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
GLVLLIISSRMLVWGAMKVAVALGMSDLVIGLTIVAVGTSLPELASSLAAARRGEHDIAL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEH
GNVVGSNLFNTLAVVGIAGAVQPMQVDPSALGRDLLVMGGFTVALFVMGYPVRRAGRINR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCH
LEGAALLCAYAAYTVWLVGVAGQSA
HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMTLPILAIVAGLVLLVYSADRFVLGSSATARHFGMPPLLIGMVIVGFGTSVPEMLVSLM
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCHHHCCCCHHHHHHHHHHCCCCHHHHHHHHH
AAMSGTPGIALGNAYGSNITNIGLILGATAVLGPVMVSSQVLRKELPILIGVTLLTAALL
HHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
WDGSLDRTNALVLLAVFFVLVGWSVYQGMHSTRDAFGQEMEQQAGTQPLALKAALGWTAA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
GLVLLIISSRMLVWGAMKVAVALGMSDLVIGLTIVAVGTSLPELASSLAAARRGEHDIAL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEH
GNVVGSNLFNTLAVVGIAGAVQPMQVDPSALGRDLLVMGGFTVALFVMGYPVRRAGRINR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCCCH
LEGAALLCAYAAYTVWLVGVAGQSA
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]