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The map label for this gene is htpG

Identifier: 78356194

GI number: 78356194

Start: 1173145

End: 1175055

Strand: Reverse

Name: htpG

Synonym: Dde_1147

Alternate gene names: 78356194

Gene position: 1175055-1173145 (Counterclockwise)

Preceding gene: 78356195

Following gene: 78356189

Centisome position: 31.5

GC content: 55.26

Gene sequence:

>1911_bases
ATGAGCAAAGAGCACGGCGCCGCCGCCGAAAAACACGAATTCCGCACCGAAGTACGCAAGCTGCTGCACATCATCACCCA
TTCTCTGTACACCAACAGAGAAATTTTTCTGCGCGAACTGGTCTCCAACGCTTCCGACGCACTGGACAAGCTGCGCTTTG
CACAGACACGGGGCGAAGCCGCTCCGGCCGCCGACCTTGACCTGAACATAGCCATAACCGTCAACGAAGAAACACGCACC
CTGACAGTCAGTGATACCGGCATCGGCATGACCCGTCAGGAACTTATCGATAACCTTGGCACCATCGCCAGCTCCGGTTC
CGAGCGTTTTCTCAAAGAACTTGCCGAAAAAGGTGAACAGGCAAGCAATATCATCGGCCGGTTCGGTGTGGGTTTTTATG
CCGTGTTCATGGTGGCCGATTCTGTAACGGTGACCACGCGCAGTGCGCTGGACGCCTCCGGCGCATGGCGCTGGACCAGT
GACGGGCTGGGCAGTTTTGAACTGGAAGAAGCCCTCGACGCGCCGGAACGCGGCACCCGCATAGACATCCGTCTGAAGGA
AGATGCCGGTGATTTTCTGAAAAAAGACCATCTGAAGGATGTCATCCGCAGGCACTCCAACTTCATCCCCTTCCCCGTTT
CGGTAGAAGGCGAACACGTCAACACCACCCCGGCCCTGTGGCGCGAACCCAGATTTCAGGTCACCGAGGAACAGTACAAA
GATTTTTATACGTTCCTCACCTTTGACACACAGGCGCCCATGGACACCATCCACCTTTCCATCGATGCGCCGGTACAGTT
CACATCTCTGGCTTTCATTCCCAATTTTGGCAACGAGCTTTTCGGGTATGACCGCGACAAATACGGACTGGACCTGTATG
TGCGCCGAGTGCTCATCAGCAAAGAATACAAGGCCCTGATTCCTGAATATCTTTCGTTCCTCAAAGGGGTTGTGGATACG
GAAGACCTGCCGCTGAACATCTCGCGCGAAACGCTGCAGGAAAATGCGCTCATCGCCAAAATCCGCCAGACGCTGGTAAA
GCAGGTGCTGGCGCATCTGGCAAAACTTGCGGAATCAGATGCCGAAAAATATGCCACCTTCTGGCGTACCCACGGACGGG
TGTTCCGCATGGGCTACAACGATTACATCAACAGAGATAAATTCATCCCGCTGCTGCGCTTCAACAGTTCCGCACTGGAT
GACGAAAAAGGTCTGTGCTCGCTGGATGACTATATCGGCCGTGCAAGAGAGGGGCAGAAGACCGTCTGGTATGTGTCCGC
ACCCAACCGTGAAGCCGCACGCCTGAACCCCCATGTGGAGATTTTCCGGCGCAAGGGCATTGAAGTGCTGTATCTGTACG
AAGCTGCAGACGAGTTCATCATGGAATCGCTCGGCAAATGGAACGAGTTTGAATTCCGCTCCGCGGAACATGCCGATGCC
GACGCGCTGAAAGACTTTGATGATGTGGAAAAGAAGGATGCGCCTGAAGCTCTGGACGAAGAAGGACGAAAAACTCTGAG
CAGCCTGCTGTCCCACATGAAAACCCTGCTGGGCGACAAGGTGGAAGACGTGCGCGAATCAGCGCGGCTTTCTGATTCTC
CGGCCTGCCTTGCCAGTAAAGACGGCGGTATGACTGCTTCCATGGAAAAACTGATGCGCGTCATGAACAAAGACGAATCA
GTGCCGCGCAAAGTGCTGGAAATCAACCCTGACCATCCGCTTACCCGAAACCTGCTGCGGCTTTACCGCGCCGATGCTGA
CGACAGGCTGCTCGCGCAGGCCACGGAACAGCTTTACGAATCCGCTTTGCTGCTTGAAGGCTACCTGCGTGATCCCCACG
CGCTTGTCGGCAGAGTGAATTCGCTGCTTGAACAGGCCACCGGCTGGTACGCAGAAGTGCGCAAACTGTAG

Upstream 100 bases:

>100_bases
CAGGCGCTGCGTATTTATGTATGCAGGCAGTGCCCCGCATGTATTGCGCAGATTCCGCTGCTGCCGCGGGTATGTATTGA
TATATTCAGGAGGAAACCAT

Downstream 100 bases:

>100_bases
GCCCCGCCATACCCATCCCGTATAAAAACGCCCCGCAGAACATTCTGCGGGGCGTTTCTTATGCGGAAGCTCAGTATATC
CCGCATGTGGCCGGTATGTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MSKEHGAAAEKHEFRTEVRKLLHIITHSLYTNREIFLRELVSNASDALDKLRFAQTRGEAAPAADLDLNIAITVNEETRT
LTVSDTGIGMTRQELIDNLGTIASSGSERFLKELAEKGEQASNIIGRFGVGFYAVFMVADSVTVTTRSALDASGAWRWTS
DGLGSFELEEALDAPERGTRIDIRLKEDAGDFLKKDHLKDVIRRHSNFIPFPVSVEGEHVNTTPALWREPRFQVTEEQYK
DFYTFLTFDTQAPMDTIHLSIDAPVQFTSLAFIPNFGNELFGYDRDKYGLDLYVRRVLISKEYKALIPEYLSFLKGVVDT
EDLPLNISRETLQENALIAKIRQTLVKQVLAHLAKLAESDAEKYATFWRTHGRVFRMGYNDYINRDKFIPLLRFNSSALD
DEKGLCSLDDYIGRAREGQKTVWYVSAPNREAARLNPHVEIFRRKGIEVLYLYEAADEFIMESLGKWNEFEFRSAEHADA
DALKDFDDVEKKDAPEALDEEGRKTLSSLLSHMKTLLGDKVEDVRESARLSDSPACLASKDGGMTASMEKLMRVMNKDES
VPRKVLEINPDHPLTRNLLRLYRADADDRLLAQATEQLYESALLLEGYLRDPHALVGRVNSLLEQATGWYAEVRKL

Sequences:

>Translated_636_residues
MSKEHGAAAEKHEFRTEVRKLLHIITHSLYTNREIFLRELVSNASDALDKLRFAQTRGEAAPAADLDLNIAITVNEETRT
LTVSDTGIGMTRQELIDNLGTIASSGSERFLKELAEKGEQASNIIGRFGVGFYAVFMVADSVTVTTRSALDASGAWRWTS
DGLGSFELEEALDAPERGTRIDIRLKEDAGDFLKKDHLKDVIRRHSNFIPFPVSVEGEHVNTTPALWREPRFQVTEEQYK
DFYTFLTFDTQAPMDTIHLSIDAPVQFTSLAFIPNFGNELFGYDRDKYGLDLYVRRVLISKEYKALIPEYLSFLKGVVDT
EDLPLNISRETLQENALIAKIRQTLVKQVLAHLAKLAESDAEKYATFWRTHGRVFRMGYNDYINRDKFIPLLRFNSSALD
DEKGLCSLDDYIGRAREGQKTVWYVSAPNREAARLNPHVEIFRRKGIEVLYLYEAADEFIMESLGKWNEFEFRSAEHADA
DALKDFDDVEKKDAPEALDEEGRKTLSSLLSHMKTLLGDKVEDVRESARLSDSPACLASKDGGMTASMEKLMRVMNKDES
VPRKVLEINPDHPLTRNLLRLYRADADDRLLAQATEQLYESALLLEGYLRDPHALVGRVNSLLEQATGWYAEVRKL
>Mature_635_residues
SKEHGAAAEKHEFRTEVRKLLHIITHSLYTNREIFLRELVSNASDALDKLRFAQTRGEAAPAADLDLNIAITVNEETRTL
TVSDTGIGMTRQELIDNLGTIASSGSERFLKELAEKGEQASNIIGRFGVGFYAVFMVADSVTVTTRSALDASGAWRWTSD
GLGSFELEEALDAPERGTRIDIRLKEDAGDFLKKDHLKDVIRRHSNFIPFPVSVEGEHVNTTPALWREPRFQVTEEQYKD
FYTFLTFDTQAPMDTIHLSIDAPVQFTSLAFIPNFGNELFGYDRDKYGLDLYVRRVLISKEYKALIPEYLSFLKGVVDTE
DLPLNISRETLQENALIAKIRQTLVKQVLAHLAKLAESDAEKYATFWRTHGRVFRMGYNDYINRDKFIPLLRFNSSALDD
EKGLCSLDDYIGRAREGQKTVWYVSAPNREAARLNPHVEIFRRKGIEVLYLYEAADEFIMESLGKWNEFEFRSAEHADAD
ALKDFDDVEKKDAPEALDEEGRKTLSSLLSHMKTLLGDKVEDVRESARLSDSPACLASKDGGMTASMEKLMRVMNKDESV
PRKVLEINPDHPLTRNLLRLYRADADDRLLAQATEQLYESALLLEGYLRDPHALVGRVNSLLEQATGWYAEVRKL

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=632, Percent_Identity=38.4493670886076, Blast_Score=419, Evalue=1e-117,
Organism=Homo sapiens, GI4507677, Length=689, Percent_Identity=35.8490566037736, Blast_Score=395, Evalue=1e-110,
Organism=Homo sapiens, GI154146191, Length=423, Percent_Identity=34.9881796690307, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI20149594, Length=423, Percent_Identity=34.51536643026, Blast_Score=232, Evalue=6e-61,
Organism=Homo sapiens, GI153792590, Length=423, Percent_Identity=34.9881796690307, Blast_Score=231, Evalue=1e-60,
Organism=Escherichia coli, GI1786679, Length=632, Percent_Identity=38.4493670886076, Blast_Score=435, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI115535205, Length=647, Percent_Identity=36.9397217928903, Blast_Score=385, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17542208, Length=684, Percent_Identity=35.8187134502924, Blast_Score=376, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17559162, Length=675, Percent_Identity=33.1851851851852, Blast_Score=369, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI115535167, Length=418, Percent_Identity=41.1483253588517, Blast_Score=295, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6325016, Length=684, Percent_Identity=34.2105263157895, Blast_Score=376, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6323840, Length=680, Percent_Identity=34.1176470588235, Blast_Score=374, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24586016, Length=649, Percent_Identity=36.055469953775, Blast_Score=394, Evalue=1e-109,
Organism=Drosophila melanogaster, GI21357739, Length=703, Percent_Identity=34.850640113798, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI17647529, Length=422, Percent_Identity=33.6492890995261, Blast_Score=243, Evalue=4e-64,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_DESDG (Q313E8)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387643.1
- ProteinModelPortal:   Q313E8
- STRING:   Q313E8
- GeneID:   3755171
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1147
- NMPDR:   fig|207559.3.peg.1321
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   DDES207559:DDE_1147-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 72196; Mature: 72065

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKEHGAAAEKHEFRTEVRKLLHIITHSLYTNREIFLRELVSNASDALDKLRFAQTRGEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APAADLDLNIAITVNEETRTLTVSDTGIGMTRQELIDNLGTIASSGSERFLKELAEKGEQ
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
ASNIIGRFGVGFYAVFMVADSVTVTTRSALDASGAWRWTSDGLGSFELEEALDAPERGTR
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCEECCCCCCCEEHHHHCCCCCCCCE
IDIRLKEDAGDFLKKDHLKDVIRRHSNFIPFPVSVEGEHVNTTPALWREPRFQVTEEQYK
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCHHHHH
DFYTFLTFDTQAPMDTIHLSIDAPVQFTSLAFIPNFGNELFGYDRDKYGLDLYVRRVLIS
HHHHEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHH
KEYKALIPEYLSFLKGVVDTEDLPLNISRETLQENALIAKIRQTLVKQVLAHLAKLAESD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEKYATFWRTHGRVFRMGYNDYINRDKFIPLLRFNSSALDDEKGLCSLDDYIGRAREGQK
HHHHHHHHHHCCEEEEECCHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCC
TVWYVSAPNREAARLNPHVEIFRRKGIEVLYLYEAADEFIMESLGKWNEFEFRSAEHADA
EEEEEECCCCCCHHCCCHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCH
DALKDFDDVEKKDAPEALDEEGRKTLSSLLSHMKTLLGDKVEDVRESARLSDSPACLASK
HHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECC
DGGMTASMEKLMRVMNKDESVPRKVLEINPDHPLTRNLLRLYRADADDRLLAQATEQLYE
CCCCHHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
SALLLEGYLRDPHALVGRVNSLLEQATGWYAEVRKL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
SKEHGAAAEKHEFRTEVRKLLHIITHSLYTNREIFLRELVSNASDALDKLRFAQTRGEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APAADLDLNIAITVNEETRTLTVSDTGIGMTRQELIDNLGTIASSGSERFLKELAEKGEQ
CCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCH
ASNIIGRFGVGFYAVFMVADSVTVTTRSALDASGAWRWTSDGLGSFELEEALDAPERGTR
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHCCCCCCCEECCCCCCCEEHHHHCCCCCCCCE
IDIRLKEDAGDFLKKDHLKDVIRRHSNFIPFPVSVEGEHVNTTPALWREPRFQVTEEQYK
EEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHCCCCCCCCHHHHH
DFYTFLTFDTQAPMDTIHLSIDAPVQFTSLAFIPNFGNELFGYDRDKYGLDLYVRRVLIS
HHHHEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCHHCCCCCCCCCHHHHHHHHHHH
KEYKALIPEYLSFLKGVVDTEDLPLNISRETLQENALIAKIRQTLVKQVLAHLAKLAESD
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEKYATFWRTHGRVFRMGYNDYINRDKFIPLLRFNSSALDDEKGLCSLDDYIGRAREGQK
HHHHHHHHHHCCEEEEECCHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHCCCCCCC
TVWYVSAPNREAARLNPHVEIFRRKGIEVLYLYEAADEFIMESLGKWNEFEFRSAEHADA
EEEEEECCCCCCHHCCCHHHHHHHCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCCH
DALKDFDDVEKKDAPEALDEEGRKTLSSLLSHMKTLLGDKVEDVRESARLSDSPACLASK
HHHHCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCEEECC
DGGMTASMEKLMRVMNKDESVPRKVLEINPDHPLTRNLLRLYRADADDRLLAQATEQLYE
CCCCHHHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHH
SALLLEGYLRDPHALVGRVNSLLEQATGWYAEVRKL
HHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA