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The map label for this gene is frr

Identifier: 78356175

GI number: 78356175

Start: 1158085

End: 1158639

Strand: Reverse

Name: frr

Synonym: Dde_1128

Alternate gene names: 78356175

Gene position: 1158639-1158085 (Counterclockwise)

Preceding gene: 78356176

Following gene: 78356174

Centisome position: 31.06

GC content: 53.51

Gene sequence:

>555_bases
ATGGATACAATTCTGCTCGAAACCGAAGAACGGATGGAAAAGGCAGTCGCCGCTCTTGACCGCGAATTCGGACGCCTGCG
CACCGGACGGGCCTCCACATCGCTTGTCGATTCCATCAAGGTGGATTACTACGGCACCCCCACGCCCATCAACCAGCTGG
CTTCCGTGGCTGTGCCCGACAGCCGCACCATCACCATTCAGCCGTGGGACCGCGGAGCTTTCGCTCTGGTTGAAAAAGCC
ATCATGCAGTCCGATCTGGGGCTTACTCCGATCAACGACGGCAAAATCATCCGCATTTCCATGCCGCCCCTTACCGAAGA
GCGCCGCAAGGAACTGGTGAAGGTAGCCAAAAAGTACACCGAAGATGCCAAGGTGGCCGTGCGCAATATCCGCCGCGACG
CCAATGAGCAGATTAAAAAGATGGAAAAAGACAAAGCCATTACTGAAGACGACATGAAACGCGGTCAGGACGAAGTGCAG
AAGCTCACTGATGCGTTTGTTGCCAAGTCTGAAAAAGTGTTGGCCAAAAAAGAAAAAGAAATCATGGAAGTATAG

Upstream 100 bases:

>100_bases
ACAACGTGCCCATCATCGTCTGCAACATGTACAAAGGCGGCATAAAACGTGCTGTCATGGGCGAAGACGTGGGAACCATA
GTGCAAGGAGGCTAACTCAC

Downstream 100 bases:

>100_bases
CAGCGCCTGCCGGCACGGCAATGCCGGAAAACATGCGCGACATGCTTTTTGCTTGCGCCGCCGGGCCATGTCCGGCGGCG
TTTTTTTTACACCCGCGGTT

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPDSRTITIQPWDRGAFALVEKA
IMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYTEDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQ
KLTDAFVAKSEKVLAKKEKEIMEV

Sequences:

>Translated_184_residues
MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPDSRTITIQPWDRGAFALVEKA
IMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYTEDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQ
KLTDAFVAKSEKVLAKKEKEIMEV
>Mature_184_residues
MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPDSRTITIQPWDRGAFALVEKA
IMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYTEDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQ
KLTDAFVAKSEKVLAKKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=29.6703296703297, Blast_Score=73, Evalue=1e-13,
Organism=Homo sapiens, GI291042689, Length=166, Percent_Identity=30.7228915662651, Blast_Score=64, Evalue=7e-11,
Organism=Escherichia coli, GI1786368, Length=177, Percent_Identity=57.0621468926554, Blast_Score=200, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24661488, Length=173, Percent_Identity=27.7456647398844, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_DESDG (Q313G7)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387624.1
- ProteinModelPortal:   Q313G7
- SMR:   Q313G7
- STRING:   Q313G7
- GeneID:   3755152
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1128
- NMPDR:   fig|207559.3.peg.1257
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   DDES207559:DDE_1128-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20821; Mature: 20821

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPD
CCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCHHHHHHHCCCC
SRTITIQPWDRGAFALVEKAIMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYT
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
EDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQKLTDAFVAKSEKVLAKKEKE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IMEV
HHCC
>Mature Secondary Structure
MDTILLETEERMEKAVAALDREFGRLRTGRASTSLVDSIKVDYYGTPTPINQLASVAVPD
CCCEEECCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEECCCCCCCCHHHHHHHCCCC
SRTITIQPWDRGAFALVEKAIMQSDLGLTPINDGKIIRISMPPLTEERRKELVKVAKKYT
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
EDAKVAVRNIRRDANEQIKKMEKDKAITEDDMKRGQDEVQKLTDAFVAKSEKVLAKKEKE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
IMEV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA