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The map label for this gene is ychM [C]

Identifier: 78356149

GI number: 78356149

Start: 1129409

End: 1131163

Strand: Reverse

Name: ychM [C]

Synonym: Dde_1102

Alternate gene names: 78356149

Gene position: 1131163-1129409 (Counterclockwise)

Preceding gene: 78356151

Following gene: 78356148

Centisome position: 30.32

GC content: 61.71

Gene sequence:

>1755_bases
ATGAAAACGGGCATCGCAGCCTTTTTCCCTTTTATGCACTGGCTGCCGGGAGTAACGGCCCGCACCCTGCGCGCAGACCT
TCTGGCAGGTCTCACGGGAGCCATCATCGTTCTGCCGCAGGGAGTGGCGTTTGCCACGCTGGCGGGACTGCCGCCTGAAT
ACGGCATATACACCGCCGTTGTCCCGGCCATCATAGCGGCGCTGTTCGGCTCTTCCATGCATCTTGTATCAGGCCCCACC
ACGGCCATCTCGCTGGTTATTTTTTCCAATGTCAGCACGCTGGCCCCTGCGGGCACACCGGACTACATATGCCTTGTGCT
CAGTCTCACGCTGATGGCCGGCCTCATCCAGCTGGCGCTGGGGCTGGCGCGGCTGGGTTCCGTGGTCAACTTTGTCTCCC
ATTCCGTGCTGACGGGCTTCACCACCGGTGCGGCCATTCTCATCGCCTCAAGCCAGCTGGGCGGATTTGCCGGTCTGTCC
GTGCCGCGCAGCGGTTTTCTGCCGCGCGACATGGCAACGTTCGTCTCCATGCTGCCGCAGGCCAGCTGGCATGCCGTGGC
CATAGCCGCAGTCACGTTTGTCACGGCGCTTTTGGTCCGCCGCGTGGATAAACGCCTTCCCGCCATGCTTATAGCCATGG
CGGCAGGAGGGCTGCTGTGTCTTGTCATTGACGGCGCAGCCAACGGAGTACGCATGGTGGGAGCCCTGCACGCCGGACTG
CCGCCCTTCTCCGTGCCGGTATTCGATCCGGAACGGCTGGGCATACTTATGCCCGGAGCGCTGGCGGTGGCCATGCTGGG
GCTTGCCGAGGCCGTATCCATTGCCAGATCCGTGGGGGCTCTTTCGCACCAGCGCATAGACAACAACCGCGAATTCATCG
GTCAGGGGCTGTCGAACATGGTGGGCTGCTTCTTTTCGGCCTACGCGTCGTCCGGTTCGTTCACCCGCACGGGTGTCAAT
TACGCCACCGGCGCCCGCACGCCGCTTTCCGCCATTTTTGCGGCGGTTCTGCTGGTGGGCATGGTTTCCGTCATGGGCGG
GCTGGCCGCGTATCTGCCGCTTCCGGCCATGGCCGGTGTCATCATGCTGGTGGCGTGGAACCTCATAGACATCGAGCACA
TCCGGCGCATCATGAGCGCGGGCAGCGGCGAGCCTCTGGTCTTTGCCGTCACGCTGCTTTCCACACTCACCGTAAAGCTG
GAATTTGCTCTCATCGCCGGAGTAGCCCTTTCGCTGCTCATCTATCTGCACCGTACCATGCACCCGCACTTCATGCCCAT
GGCACCCGTGCTCATAGACGGCATGCGCCACATAATCAGACAGGAAAACCGCAACCTGCCCGAATGCCCGCAGCTTAAAA
TACTGCGGCTGGACGGCTCGCTGTTTTTCGGCGCAGCCGAACATGTGGCCGAAGAGCTGGAAAATATCGTGGCCGCCAAT
CCGGGCCAGAACCATATCCTGATCGTTGCCAGCGGCATCAACTTTATTGATTACTCCGGCTGCGAAACCATCTTTGAAGA
ACGCAAACTGCTGCAGGCCGCAGGCGTGCGCCTGTACATGTGCTCTGCCAACCCCGGCGTGCGCGCGGCCATGGAACGGC
TGCAATGCGGTCCCATAATTCCCATATATGAAGACAAGGCGGAAGCCATTGCCACCATCACCCCCCAGCTGGACATGAAC
CGCTGCGCCGTATGCCGTCTGCGGGTGTTCCACGAATGCGCCGGACTGCCCGGCCCGGAAATGACCGCGGAGTAA

Upstream 100 bases:

>100_bases
TAATGTACAATTCTTGAACAGACCGCCACTACACGCTATAGTGAAAAATACGGCCGCGCGCACCGTGGCCGGACATCATA
CATCACGGAGTCATGTACAC

Downstream 100 bases:

>100_bases
CCCTGTTGCCCGGACAGGGCCGGACACAGTTCGCGCCCCGTATAAGACGCAGAATGTCTGCCGGCAGCCGTACGGCACAG
CCCGCACCGGCCGGTACCGC

Product: high affinity sulfate transporter SulP

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 584; Mature: 584

Protein sequence:

>584_residues
MKTGIAAFFPFMHWLPGVTARTLRADLLAGLTGAIIVLPQGVAFATLAGLPPEYGIYTAVVPAIIAALFGSSMHLVSGPT
TAISLVIFSNVSTLAPAGTPDYICLVLSLTLMAGLIQLALGLARLGSVVNFVSHSVLTGFTTGAAILIASSQLGGFAGLS
VPRSGFLPRDMATFVSMLPQASWHAVAIAAVTFVTALLVRRVDKRLPAMLIAMAAGGLLCLVIDGAANGVRMVGALHAGL
PPFSVPVFDPERLGILMPGALAVAMLGLAEAVSIARSVGALSHQRIDNNREFIGQGLSNMVGCFFSAYASSGSFTRTGVN
YATGARTPLSAIFAAVLLVGMVSVMGGLAAYLPLPAMAGVIMLVAWNLIDIEHIRRIMSAGSGEPLVFAVTLLSTLTVKL
EFALIAGVALSLLIYLHRTMHPHFMPMAPVLIDGMRHIIRQENRNLPECPQLKILRLDGSLFFGAAEHVAEELENIVAAN
PGQNHILIVASGINFIDYSGCETIFEERKLLQAAGVRLYMCSANPGVRAAMERLQCGPIIPIYEDKAEAIATITPQLDMN
RCAVCRLRVFHECAGLPGPEMTAE

Sequences:

>Translated_584_residues
MKTGIAAFFPFMHWLPGVTARTLRADLLAGLTGAIIVLPQGVAFATLAGLPPEYGIYTAVVPAIIAALFGSSMHLVSGPT
TAISLVIFSNVSTLAPAGTPDYICLVLSLTLMAGLIQLALGLARLGSVVNFVSHSVLTGFTTGAAILIASSQLGGFAGLS
VPRSGFLPRDMATFVSMLPQASWHAVAIAAVTFVTALLVRRVDKRLPAMLIAMAAGGLLCLVIDGAANGVRMVGALHAGL
PPFSVPVFDPERLGILMPGALAVAMLGLAEAVSIARSVGALSHQRIDNNREFIGQGLSNMVGCFFSAYASSGSFTRTGVN
YATGARTPLSAIFAAVLLVGMVSVMGGLAAYLPLPAMAGVIMLVAWNLIDIEHIRRIMSAGSGEPLVFAVTLLSTLTVKL
EFALIAGVALSLLIYLHRTMHPHFMPMAPVLIDGMRHIIRQENRNLPECPQLKILRLDGSLFFGAAEHVAEELENIVAAN
PGQNHILIVASGINFIDYSGCETIFEERKLLQAAGVRLYMCSANPGVRAAMERLQCGPIIPIYEDKAEAIATITPQLDMN
RCAVCRLRVFHECAGLPGPEMTAE
>Mature_584_residues
MKTGIAAFFPFMHWLPGVTARTLRADLLAGLTGAIIVLPQGVAFATLAGLPPEYGIYTAVVPAIIAALFGSSMHLVSGPT
TAISLVIFSNVSTLAPAGTPDYICLVLSLTLMAGLIQLALGLARLGSVVNFVSHSVLTGFTTGAAILIASSQLGGFAGLS
VPRSGFLPRDMATFVSMLPQASWHAVAIAAVTFVTALLVRRVDKRLPAMLIAMAAGGLLCLVIDGAANGVRMVGALHAGL
PPFSVPVFDPERLGILMPGALAVAMLGLAEAVSIARSVGALSHQRIDNNREFIGQGLSNMVGCFFSAYASSGSFTRTGVN
YATGARTPLSAIFAAVLLVGMVSVMGGLAAYLPLPAMAGVIMLVAWNLIDIEHIRRIMSAGSGEPLVFAVTLLSTLTVKL
EFALIAGVALSLLIYLHRTMHPHFMPMAPVLIDGMRHIIRQENRNLPECPQLKILRLDGSLFFGAAEHVAEELENIVAAN
PGQNHILIVASGINFIDYSGCETIFEERKLLQAAGVRLYMCSANPGVRAAMERLQCGPIIPIYEDKAEAIATITPQLDMN
RCAVCRLRVFHECAGLPGPEMTAE

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI262206105, Length=448, Percent_Identity=29.6875, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI262206075, Length=448, Percent_Identity=29.6875, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI262206069, Length=448, Percent_Identity=29.6875, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI262206063, Length=448, Percent_Identity=29.6875, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI45827800, Length=513, Percent_Identity=25.7309941520468, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI39752683, Length=513, Percent_Identity=25.7309941520468, Blast_Score=171, Evalue=3e-42,
Organism=Homo sapiens, GI94721255, Length=493, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI94721253, Length=493, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI94721259, Length=493, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI94721257, Length=493, Percent_Identity=29.4117647058824, Blast_Score=166, Evalue=7e-41,
Organism=Homo sapiens, GI4557535, Length=520, Percent_Identity=26.3461538461538, Blast_Score=163, Evalue=5e-40,
Organism=Homo sapiens, GI269784651, Length=512, Percent_Identity=25.5859375, Blast_Score=160, Evalue=3e-39,
Organism=Homo sapiens, GI45827802, Length=450, Percent_Identity=26.6666666666667, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI100913030, Length=621, Percent_Identity=24.6376811594203, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI20336282, Length=525, Percent_Identity=24.1904761904762, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI16306483, Length=525, Percent_Identity=24.1904761904762, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI4505697, Length=505, Percent_Identity=23.1683168316832, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI47131207, Length=616, Percent_Identity=24.8376623376623, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI20336272, Length=616, Percent_Identity=24.8376623376623, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI16418413, Length=503, Percent_Identity=23.2604373757455, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217272867, Length=503, Percent_Identity=23.2604373757455, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI65506789, Length=370, Percent_Identity=25.4054054054054, Blast_Score=97, Evalue=6e-20,
Organism=Homo sapiens, GI45827804, Length=176, Percent_Identity=32.3863636363636, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI16418457, Length=506, Percent_Identity=22.3320158102767, Blast_Score=90, Evalue=6e-18,
Organism=Homo sapiens, GI301601599, Length=506, Percent_Identity=22.3320158102767, Blast_Score=90, Evalue=6e-18,
Organism=Escherichia coli, GI87081859, Length=552, Percent_Identity=27.1739130434783, Blast_Score=158, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17566848, Length=559, Percent_Identity=24.865831842576, Blast_Score=168, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI86564196, Length=604, Percent_Identity=23.3443708609272, Blast_Score=155, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI193203292, Length=519, Percent_Identity=24.8554913294798, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI86565215, Length=509, Percent_Identity=25.3438113948919, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17562578, Length=621, Percent_Identity=23.1884057971014, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17551690, Length=508, Percent_Identity=22.0472440944882, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI86565213, Length=186, Percent_Identity=34.4086021505376, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI86564876, Length=381, Percent_Identity=22.3097112860892, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI86565209, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI86565211, Length=246, Percent_Identity=26.4227642276423, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325260, Length=593, Percent_Identity=24.114671163575, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323121, Length=456, Percent_Identity=26.0964912280702, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319771, Length=457, Percent_Identity=24.507658643326, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19922482, Length=561, Percent_Identity=26.9162210338681, Blast_Score=184, Evalue=2e-46,
Organism=Drosophila melanogaster, GI85815873, Length=492, Percent_Identity=28.8617886178862, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24663084, Length=560, Percent_Identity=25.7142857142857, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21357695, Length=560, Percent_Identity=25.7142857142857, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24647160, Length=441, Percent_Identity=25.8503401360544, Blast_Score=148, Evalue=9e-36,
Organism=Drosophila melanogaster, GI21355087, Length=441, Percent_Identity=25.8503401360544, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24651449, Length=471, Percent_Identity=23.9915074309979, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24649801, Length=581, Percent_Identity=21.5146299483649, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24666186, Length=637, Percent_Identity=24.8037676609105, Blast_Score=130, Evalue=4e-30,
Organism=Drosophila melanogaster, GI21358229, Length=489, Percent_Identity=23.3128834355828, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI21358633, Length=528, Percent_Identity=23.8636363636364, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 61516; Mature: 61516

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTGIAAFFPFMHWLPGVTARTLRADLLAGLTGAIIVLPQGVAFATLAGLPPEYGIYTAV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHHH
VPAIIAALFGSSMHLVSGPTTAISLVIFSNVSTLAPAGTPDYICLVLSLTLMAGLIQLAL
HHHHHHHHHCCCCEEECCCHHHEEHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLARLGSVVNFVSHSVLTGFTTGAAILIASSQLGGFAGLSVPRSGFLPRDMATFVSMLPQ
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
ASWHAVAIAAVTFVTALLVRRVDKRLPAMLIAMAAGGLLCLVIDGAANGVRMVGALHAGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCC
PPFSVPVFDPERLGILMPGALAVAMLGLAEAVSIARSVGALSHQRIDNNREFIGQGLSNM
CCCCCCCCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
VGCFFSAYASSGSFTRTGVNYATGARTPLSAIFAAVLLVGMVSVMGGLAAYLPLPAMAGV
HHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVAWNLIDIEHIRRIMSAGSGEPLVFAVTLLSTLTVKLEFALIAGVALSLLIYLHRTM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPHFMPMAPVLIDGMRHIIRQENRNLPECPQLKILRLDGSLFFGAAEHVAEELENIVAAN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHCCC
PGQNHILIVASGINFIDYSGCETIFEERKLLQAAGVRLYMCSANPGVRAAMERLQCGPII
CCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCC
PIYEDKAEAIATITPQLDMNRCAVCRLRVFHECAGLPGPEMTAE
CEECCCCCHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKTGIAAFFPFMHWLPGVTARTLRADLLAGLTGAIIVLPQGVAFATLAGLPPEYGIYTAV
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCCCCHHHHH
VPAIIAALFGSSMHLVSGPTTAISLVIFSNVSTLAPAGTPDYICLVLSLTLMAGLIQLAL
HHHHHHHHHCCCCEEECCCHHHEEHHHHHCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
GLARLGSVVNFVSHSVLTGFTTGAAILIASSQLGGFAGLSVPRSGFLPRDMATFVSMLPQ
HHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
ASWHAVAIAAVTFVTALLVRRVDKRLPAMLIAMAAGGLLCLVIDGAANGVRMVGALHAGL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCC
PPFSVPVFDPERLGILMPGALAVAMLGLAEAVSIARSVGALSHQRIDNNREFIGQGLSNM
CCCCCCCCCHHHCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCHHHH
VGCFFSAYASSGSFTRTGVNYATGARTPLSAIFAAVLLVGMVSVMGGLAAYLPLPAMAGV
HHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IMLVAWNLIDIEHIRRIMSAGSGEPLVFAVTLLSTLTVKLEFALIAGVALSLLIYLHRTM
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
HPHFMPMAPVLIDGMRHIIRQENRNLPECPQLKILRLDGSLFFGAAEHVAEELENIVAAN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCEEHHHHHHHHHHHHHHHCCC
PGQNHILIVASGINFIDYSGCETIFEERKLLQAAGVRLYMCSANPGVRAAMERLQCGPII
CCCCEEEEEECCCCEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCC
PIYEDKAEAIATITPQLDMNRCAVCRLRVFHECAGLPGPEMTAE
CEECCCCCHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]