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The map label for this gene is rnhB

Identifier: 78356141

GI number: 78356141

Start: 1123753

End: 1124544

Strand: Reverse

Name: rnhB

Synonym: Dde_1094

Alternate gene names: 78356141

Gene position: 1124544-1123753 (Counterclockwise)

Preceding gene: 78356142

Following gene: 78356140

Centisome position: 30.15

GC content: 62.63

Gene sequence:

>792_bases
ATGGCCGCACGCACAAAAAACGGCCTCACGGCCTCTGCTTCCGGCATGCAGTCTCTGCTGCCGCATACTCTGCCTCACGC
TGACCCCGCCGGTCCGCGCGATTCTCTGTACCCTGCCTTTTTTACCGGCATAGACGAAGCCGGTCGCGGCTGTCTGGCCG
GACCGGTTGTTGCTGCCGCTGTAATTCTGCCGCCTGCCGGTGCCCCTGCAGCGCCGCACATTGCCGCTGCCCTTTCCGGC
CTTACCGACTCTAAAAAGCTTTCGGAAAAACGCCGCCTGACACTGGAACCGGCCATAAAGTCGTGCGCCGTGCGCTGGGG
CGTGGGCGTTGTGTGGCCTCAGGTCATAGACCGCATCAACATTCTTCAGGCCACTTACCGCGCCATGAGTCTGGCGGTAC
GTCACCTGCGCGGCGGCGGCGCGGCAGCCAGCATGCCTGCCGGTCTTCCGCCTGTTTTTCTTGCCGTCGACGGCGACAAA
ACCATTCCCGGACAGGTGCTGCAGGCCGTCACCGGCCTCAGTGTGCCGCAGGAAGCCATAGTGGGCGGAGACGGCTGTGT
CATGGCCATATCCGCCGCTTCGGTGCTGGCAAAAACATTTCGCGACAGACTGATGACGGCGCTGGACAAACGTTACTCCG
GATATGGTTTCGCCACGCACAAAGGATACGGTACAGCGGCTCACATCGAGGCTATCCGCAGGCTAGGTCCCTGCCGCATG
CACCGCCTGTCTTTTGCCAAAGTGAAACCGGCGGCCGCCCCGCATGCCGCCGACCAGAACACGCTATGGTAG

Upstream 100 bases:

>100_bases
CGCCCGTATCAAGCCGCTCAAGACCTGGTAGTCATACGAAGCCGGAAAGGGGGCTGCTCTCGCACGCCCCCTTTTTTTTC
GTGATCATCCGGGCACAGCC

Downstream 100 bases:

>100_bases
CCCGCCGCGCCGCAGGCAGCTGTCCCGCGCACATTGCCGCGGGCCGTCTGGGTGAAGAAGCGGCCTGCGCCTATCTTGCC
GCATCGGGCATGCGCATTTT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MAARTKNGLTASASGMQSLLPHTLPHADPAGPRDSLYPAFFTGIDEAGRGCLAGPVVAAAVILPPAGAPAAPHIAAALSG
LTDSKKLSEKRRLTLEPAIKSCAVRWGVGVVWPQVIDRINILQATYRAMSLAVRHLRGGGAAASMPAGLPPVFLAVDGDK
TIPGQVLQAVTGLSVPQEAIVGGDGCVMAISAASVLAKTFRDRLMTALDKRYSGYGFATHKGYGTAAHIEAIRRLGPCRM
HRLSFAKVKPAAAPHAADQNTLW

Sequences:

>Translated_263_residues
MAARTKNGLTASASGMQSLLPHTLPHADPAGPRDSLYPAFFTGIDEAGRGCLAGPVVAAAVILPPAGAPAAPHIAAALSG
LTDSKKLSEKRRLTLEPAIKSCAVRWGVGVVWPQVIDRINILQATYRAMSLAVRHLRGGGAAASMPAGLPPVFLAVDGDK
TIPGQVLQAVTGLSVPQEAIVGGDGCVMAISAASVLAKTFRDRLMTALDKRYSGYGFATHKGYGTAAHIEAIRRLGPCRM
HRLSFAKVKPAAAPHAADQNTLW
>Mature_262_residues
AARTKNGLTASASGMQSLLPHTLPHADPAGPRDSLYPAFFTGIDEAGRGCLAGPVVAAAVILPPAGAPAAPHIAAALSGL
TDSKKLSEKRRLTLEPAIKSCAVRWGVGVVWPQVIDRINILQATYRAMSLAVRHLRGGGAAASMPAGLPPVFLAVDGDKT
IPGQVLQAVTGLSVPQEAIVGGDGCVMAISAASVLAKTFRDRLMTALDKRYSGYGFATHKGYGTAAHIEAIRRLGPCRMH
RLSFAKVKPAAAPHAADQNTLW

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=220, Percent_Identity=43.1818181818182, Blast_Score=144, Evalue=7e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_DESDG (Q313K1)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387590.1
- ProteinModelPortal:   Q313K1
- SMR:   Q313K1
- STRING:   Q313K1
- GeneID:   3755443
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1094
- NMPDR:   fig|207559.3.peg.923
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   DDES207559:DDE_1094-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 27308; Mature: 27177

Theoretical pI: Translated: 10.46; Mature: 10.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARTKNGLTASASGMQSLLPHTLPHADPAGPRDSLYPAFFTGIDEAGRGCLAGPVVAAA
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHCCCCHHHHHHHHH
VILPPAGAPAAPHIAAALSGLTDSKKLSEKRRLTLEPAIKSCAVRWGVGVVWPQVIDRIN
HHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ILQATYRAMSLAVRHLRGGGAAASMPAGLPPVFLAVDGDKTIPGQVLQAVTGLSVPQEAI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHH
VGGDGCVMAISAASVLAKTFRDRLMTALDKRYSGYGFATHKGYGTAAHIEAIRRLGPCRM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCHHHH
HRLSFAKVKPAAAPHAADQNTLW
HHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AARTKNGLTASASGMQSLLPHTLPHADPAGPRDSLYPAFFTGIDEAGRGCLAGPVVAAA
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCHHHHCCCCHHHHHHHHH
VILPPAGAPAAPHIAAALSGLTDSKKLSEKRRLTLEPAIKSCAVRWGVGVVWPQVIDRIN
HHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
ILQATYRAMSLAVRHLRGGGAAASMPAGLPPVFLAVDGDKTIPGQVLQAVTGLSVPQEAI
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCHHHH
VGGDGCVMAISAASVLAKTFRDRLMTALDKRYSGYGFATHKGYGTAAHIEAIRRLGPCRM
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCHHHH
HRLSFAKVKPAAAPHAADQNTLW
HHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA