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The map label for this gene is hisK [H]

Identifier: 78356104

GI number: 78356104

Start: 1084134

End: 1084958

Strand: Reverse

Name: hisK [H]

Synonym: Dde_1057

Alternate gene names: 78356104

Gene position: 1084958-1084134 (Counterclockwise)

Preceding gene: 78356105

Following gene: 78356103

Centisome position: 29.09

GC content: 55.52

Gene sequence:

>825_bases
ATGATCAAAACCGATACTCACCTGCACACGCTGCACTCGCACGGCAAGGCGGGCGTGACAGAAATGTTTCATGCCGCCCG
TAAAAAGGGCATAGACATCATCGGATTTTCCGAACATTCGCCCCGGCCGGAAACACACAGCTACCCCAGCGATTACCAGC
CGAAGCTCATAGAAGGTTTTCCCACCTATGTGGCGGACGTAAAACGGCTGCGCGAAGAATTTAAAAATGAAGCCACGGTG
CTTTTCGGTCTTGAAATGGACTGGATGGAAGGCAGCGAGACATTCATAGCAGACACCCTGAAAGCCCATGACTTTGACTA
TGTCATAGGCGGCATTCATTTTCTGGATACATGGGGCTTTGATTACCGCAAAGAAGACTGGCAGGTGCTGAGCGAGGCGC
AGCAGGTGTCGCTGTACAACCGTTTTTTTGCCACCATGCAGGCCATGGCGCAGACGGGCCTTTTCAACATAGTGGCCCAC
CCCGACATCATCAAAATTTTCAGCATTGACCTGTTCCGCGAATGGGCGGCAGGAGACGAAGCCCGACAGATGTTCCGGCA
GGCGCTGACCGCCGTCCACGAGGCCGGCATGGCCATCGAAGTATCTTCTGCCGGTCTGCGCAAACCCTGCGCCGAAATTT
ATCCATGCCCGCAGTTTATGGAACTGGCAGCCGAAATGGGCATCCCCGTTGCCTTCGGGTCCGACGCACACAGCGAAGCC
TCGGTGGGGTACGCCTTTGACCGGCTGGAACAGTACGCGCGGGACTTCGGCTATAACGACAGCGTCTACTTTGTAAAACG
GCGCATGCACTCGCGGCCGTTCTGA

Upstream 100 bases:

>100_bases
GCCATTGCCACTGTAGTACACAACCCCAAACAATAGCCGCGCCCGCGCAGTCCGCGCCTGTGCCCTCTGCGTCCGACGCG
GCCCAAAACCGGATGCCGCC

Downstream 100 bases:

>100_bases
CCCTGACGCGCGGCTGCCGTCTGCGCTGCATATGTCCGCCATACTCAGGGCAGGGTGCGTTTCCGTGCGCCCCTGCCCTG
CTCCATGCGGCACGGGCACA

Product: histidinol-phosphate phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MIKTDTHLHTLHSHGKAGVTEMFHAARKKGIDIIGFSEHSPRPETHSYPSDYQPKLIEGFPTYVADVKRLREEFKNEATV
LFGLEMDWMEGSETFIADTLKAHDFDYVIGGIHFLDTWGFDYRKEDWQVLSEAQQVSLYNRFFATMQAMAQTGLFNIVAH
PDIIKIFSIDLFREWAAGDEARQMFRQALTAVHEAGMAIEVSSAGLRKPCAEIYPCPQFMELAAEMGIPVAFGSDAHSEA
SVGYAFDRLEQYARDFGYNDSVYFVKRRMHSRPF

Sequences:

>Translated_274_residues
MIKTDTHLHTLHSHGKAGVTEMFHAARKKGIDIIGFSEHSPRPETHSYPSDYQPKLIEGFPTYVADVKRLREEFKNEATV
LFGLEMDWMEGSETFIADTLKAHDFDYVIGGIHFLDTWGFDYRKEDWQVLSEAQQVSLYNRFFATMQAMAQTGLFNIVAH
PDIIKIFSIDLFREWAAGDEARQMFRQALTAVHEAGMAIEVSSAGLRKPCAEIYPCPQFMELAAEMGIPVAFGSDAHSEA
SVGYAFDRLEQYARDFGYNDSVYFVKRRMHSRPF
>Mature_274_residues
MIKTDTHLHTLHSHGKAGVTEMFHAARKKGIDIIGFSEHSPRPETHSYPSDYQPKLIEGFPTYVADVKRLREEFKNEATV
LFGLEMDWMEGSETFIADTLKAHDFDYVIGGIHFLDTWGFDYRKEDWQVLSEAQQVSLYNRFFATMQAMAQTGLFNIVAH
PDIIKIFSIDLFREWAAGDEARQMFRQALTAVHEAGMAIEVSSAGLRKPCAEIYPCPQFMELAAEMGIPVAFGSDAHSEA
SVGYAFDRLEQYARDFGYNDSVYFVKRRMHSRPF

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 31285; Mature: 31285

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKTDTHLHTLHSHGKAGVTEMFHAARKKGIDIIGFSEHSPRPETHSYPSDYQPKLIEGF
CCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCC
PTYVADVKRLREEFKNEATVLFGLEMDWMEGSETFIADTLKAHDFDYVIGGIHFLDTWGF
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
DYRKEDWQVLSEAQQVSLYNRFFATMQAMAQTGLFNIVAHPDIIKIFSIDLFREWAAGDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCHH
ARQMFRQALTAVHEAGMAIEVSSAGLRKPCAEIYPCPQFMELAAEMGIPVAFGSDAHSEA
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCCEEECCCCCCCC
SVGYAFDRLEQYARDFGYNDSVYFVKRRMHSRPF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MIKTDTHLHTLHSHGKAGVTEMFHAARKKGIDIIGFSEHSPRPETHSYPSDYQPKLIEGF
CCCCCCHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCC
PTYVADVKRLREEFKNEATVLFGLEMDWMEGSETFIADTLKAHDFDYVIGGIHFLDTWGF
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
DYRKEDWQVLSEAQQVSLYNRFFATMQAMAQTGLFNIVAHPDIIKIFSIDLFREWAAGDE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCHH
ARQMFRQALTAVHEAGMAIEVSSAGLRKPCAEIYPCPQFMELAAEMGIPVAFGSDAHSEA
HHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHCCCHHHHHHHHHCCCCEEECCCCCCCC
SVGYAFDRLEQYARDFGYNDSVYFVKRRMHSRPF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]