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The map label for this gene is htpX [H]

Identifier: 78356098

GI number: 78356098

Start: 1079159

End: 1080010

Strand: Reverse

Name: htpX [H]

Synonym: Dde_1051

Alternate gene names: 78356098

Gene position: 1080010-1079159 (Counterclockwise)

Preceding gene: 78356099

Following gene: 78356096

Centisome position: 28.95

GC content: 58.8

Gene sequence:

>852_bases
ATGACCAGTCAACTGAAGACCGTCCTTCTGCTTGCGCTGCTCTCCGGCCTTATCATTGTGATGGGCGGGGTAATGGGCGG
CCGGACTGGACTTTTCTTCGCTTTTGCCTTCGCCCTGCTGATGAACGTGGGCAGCTACTGGTATTCCGACAAAATAGTCC
TGAAAATGTACAACGCCCGCGAGGTCAGTCCTTCCGAGGCCCCCATGCTGCACGCCATGGTTGACGAGGTGGTCATGCGC
GCCGGCATTCCCAAGCCCCGCGTGTGTATCATTCCCGAACAGACACCCAACGCATTTGCCACAGGCCGCAACCCCGAACA
CGGGGTGGTGGCGGTGACAGAAGGCATCATGCACCTGCTGACCCCCGAAGAGCTAAAAGGGGTTATCGCCCATGAAGTTG
GGCACATAGCAAACAGAGACATTCTGGTGCAGAGCGTTGCCGGTGTCATGGCTTCGGTCATTGTCATGCTGGGCAACATA
CTGCAGTTCACCGCCATTTTCGGCGGCGGAAACAATGACGAGGAAGGCGGCGGAAATCCCATTGCAGCGCTGGCCATGGC
GTTTCTGGCTCCCGTTGCCGCATCGCTCATCCAGTTCGCCATTTCACGCTCGCGCGAATTCATGGCGGATGAAGCCGGAG
CCCGGTATTCCGGCAATCCCATGTATCTTGCCAGCGCCCTGCAGAAACTGGGGGCCTACAGCGGCAGAATACCCATGCAA
AGCGGCAATCAGGCCACAGCGCACATGTTCATTGTCAACCCGTTCAGCGGCGTGCGTATGGCCGAACTGTTCAGCACGCA
CCCGCCCATGGAAGAGCGCATCCGCCGTCTGCAGCAGATGGCCGGCAGATAG

Upstream 100 bases:

>100_bases
TATTGTTCCTCCCTTCTGACGTGTTTTCCCGCGATACCTGCGGGATAAACATCTGCAAGCTACACAGAACACACAGTTTA
CGGATAAAAGGAGACCTTCG

Downstream 100 bases:

>100_bases
CACCGCGCTTACATGCCCGACTAAAATCAAAGGCCGCCTCTGAAAGAGGCGGCCTTTTTCCGTTTGCAGGAAGCACCATG
CCGACTTATCGGTGCTCCGT

Product: HtpX-2 peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTSQLKTVLLLALLSGLIIVMGGVMGGRTGLFFAFAFALLMNVGSYWYSDKIVLKMYNAREVSPSEAPMLHAMVDEVVMR
AGIPKPRVCIIPEQTPNAFATGRNPEHGVVAVTEGIMHLLTPEELKGVIAHEVGHIANRDILVQSVAGVMASVIVMLGNI
LQFTAIFGGGNNDEEGGGNPIAALAMAFLAPVAASLIQFAISRSREFMADEAGARYSGNPMYLASALQKLGAYSGRIPMQ
SGNQATAHMFIVNPFSGVRMAELFSTHPPMEERIRRLQQMAGR

Sequences:

>Translated_283_residues
MTSQLKTVLLLALLSGLIIVMGGVMGGRTGLFFAFAFALLMNVGSYWYSDKIVLKMYNAREVSPSEAPMLHAMVDEVVMR
AGIPKPRVCIIPEQTPNAFATGRNPEHGVVAVTEGIMHLLTPEELKGVIAHEVGHIANRDILVQSVAGVMASVIVMLGNI
LQFTAIFGGGNNDEEGGGNPIAALAMAFLAPVAASLIQFAISRSREFMADEAGARYSGNPMYLASALQKLGAYSGRIPMQ
SGNQATAHMFIVNPFSGVRMAELFSTHPPMEERIRRLQQMAGR
>Mature_282_residues
TSQLKTVLLLALLSGLIIVMGGVMGGRTGLFFAFAFALLMNVGSYWYSDKIVLKMYNAREVSPSEAPMLHAMVDEVVMRA
GIPKPRVCIIPEQTPNAFATGRNPEHGVVAVTEGIMHLLTPEELKGVIAHEVGHIANRDILVQSVAGVMASVIVMLGNIL
QFTAIFGGGNNDEEGGGNPIAALAMAFLAPVAASLIQFAISRSREFMADEAGARYSGNPMYLASALQKLGAYSGRIPMQS
GNQATAHMFIVNPFSGVRMAELFSTHPPMEERIRRLQQMAGR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=207, Percent_Identity=36.7149758454106, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30391; Mature: 30260

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
6.4 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQLKTVLLLALLSGLIIVMGGVMGGRTGLFFAFAFALLMNVGSYWYSDKIVLKMYNAR
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
EVSPSEAPMLHAMVDEVVMRAGIPKPRVCIIPEQTPNAFATGRNPEHGVVAVTEGIMHLL
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHC
TPEELKGVIAHEVGHIANRDILVQSVAGVMASVIVMLGNILQFTAIFGGGNNDEEGGGNP
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IAALAMAFLAPVAASLIQFAISRSREFMADEAGARYSGNPMYLASALQKLGAYSGRIPMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
SGNQATAHMFIVNPFSGVRMAELFSTHPPMEERIRRLQQMAGR
CCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSQLKTVLLLALLSGLIIVMGGVMGGRTGLFFAFAFALLMNVGSYWYSDKIVLKMYNAR
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
EVSPSEAPMLHAMVDEVVMRAGIPKPRVCIIPEQTPNAFATGRNPEHGVVAVTEGIMHLL
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCEEHHHHHHHHHC
TPEELKGVIAHEVGHIANRDILVQSVAGVMASVIVMLGNILQFTAIFGGGNNDEEGGGNP
CHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
IAALAMAFLAPVAASLIQFAISRSREFMADEAGARYSGNPMYLASALQKLGAYSGRIPMQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
SGNQATAHMFIVNPFSGVRMAELFSTHPPMEERIRRLQQMAGR
CCCCCEEEEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA