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The map label for this gene is murG

Identifier: 78356089

GI number: 78356089

Start: 1070310

End: 1071431

Strand: Direct

Name: murG

Synonym: Dde_1042

Alternate gene names: 78356089

Gene position: 1070310-1071431 (Clockwise)

Preceding gene: 78356088

Following gene: 78356090

Centisome position: 28.69

GC content: 61.5

Gene sequence:

>1122_bases
ATGAAGCGCGTGCTGCTGACAACCGGTGGTACAGGCGGGCATATCTTTCCCGCACTGGCCGTGGCCGAAGAAATACGCAG
GCAGTATCCTGCCGCAGATATTCTTTTTGTGGGCGGAAGTTACGGGCCTGAAGCACGCATCGTGCCCGCGCACGGGATAC
GCTTTGAAGGACTGCCCGTACGCGGAGTCATGGGGCGCGGCTTAAAGGCGCCGCTGGCTCTTGCTGCCATGACAGCCGGG
GTGGCCAGAGGGATGCGGCTGGTGGGCCGCTTTAACCCGGATGTGGTTATCGGGTTTGGCGGATATGCCGCCTTTGCCGC
CATGGTGGCTGCAAAGCTGCGCGAAAAGCCCTGTGCCGTGCACGAACAGAACAGTGTGCCCGGCATGGCCAACAGGCTGC
TGGCAAAGATAGCGGACAGGGTTTTTATCTCGTTTCCCGATCCGCAGGAGTATTTTCTGCAGCGCAAGACTGTGCTTACG
GGAAATCCCGTGCGTGCGGCCATTGCCGCGGCCGGAGCGCACCGCGCAGGGCATGTGCCGGCGTGCAGGCTGCTTGTGAT
GGGAGGCAGTCAGGGGGCGCACGCCCTTAACCTTGCCGTCGTAAACATGCTGCCGCAATTGCGGGACGCCGGTGTGGAAA
TACTGCACCAGACAGGCGCTGCCGATCTGGAAACCGTACGGTCGGCATACGACAAGGCCGGCGTGCAGGCCACGGTGGTT
GATTTTGTGGAAGATATGGCTGCTGCGTATGCCTGGACAGACCTTGCACTGTGCCGGGCCGGAGCCACAACGGTATTTGA
ACTGGCCGCCGCCGGAGTGCCCGCCGTGTTTGTGCCGTTTCCTTTTGCCACGCACGACCATCAGACCGCCAACGCTGCTT
TTCTGGCGGACCGCGGAGCGGCACAAAGCATAGCGCAGCGCGATCTTGAGTCCATGCCGCCCGCCGTGCTGGCAGGACAG
ATCATTGACCTGCTGAAAGACCACGGACGGCTGCAGGGCATGTCTGCGGCGATGCGCAGGATGGCAAGACCCGAGGCTGC
AGCCGCCATAGTGAGCGGCGCAAAAGATTTGATAAGGAAAAAGCCCTTAAGGTCGCTGGTGCCTGAGCGGGAAGGAGAAT
AA

Upstream 100 bases:

>100_bases
TACCCATGCCGTTTCTGAGCTACGGGGGCAGCAGTCTGCTGGGCACGCTTATCTGTGTCGGCCTGCTGCTTAATTTCTCG
CGCAGCGCAAGGAGTACACA

Downstream 100 bases:

>100_bases
CGGCGTGATCGGAAAAGTTTTCAGAATTCATATGGTCGGCATAGGCGGCACGGGAATGTGCGGCATAGCCGAGGTGCTTC
TCAATCTCGGTTTCGAAGTG

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKRVLLTTGGTGGHIFPALAVAEEIRRQYPAADILFVGGSYGPEARIVPAHGIRFEGLPVRGVMGRGLKAPLALAAMTAG
VARGMRLVGRFNPDVVIGFGGYAAFAAMVAAKLREKPCAVHEQNSVPGMANRLLAKIADRVFISFPDPQEYFLQRKTVLT
GNPVRAAIAAAGAHRAGHVPACRLLVMGGSQGAHALNLAVVNMLPQLRDAGVEILHQTGAADLETVRSAYDKAGVQATVV
DFVEDMAAAYAWTDLALCRAGATTVFELAAAGVPAVFVPFPFATHDHQTANAAFLADRGAAQSIAQRDLESMPPAVLAGQ
IIDLLKDHGRLQGMSAAMRRMARPEAAAAIVSGAKDLIRKKPLRSLVPEREGE

Sequences:

>Translated_373_residues
MKRVLLTTGGTGGHIFPALAVAEEIRRQYPAADILFVGGSYGPEARIVPAHGIRFEGLPVRGVMGRGLKAPLALAAMTAG
VARGMRLVGRFNPDVVIGFGGYAAFAAMVAAKLREKPCAVHEQNSVPGMANRLLAKIADRVFISFPDPQEYFLQRKTVLT
GNPVRAAIAAAGAHRAGHVPACRLLVMGGSQGAHALNLAVVNMLPQLRDAGVEILHQTGAADLETVRSAYDKAGVQATVV
DFVEDMAAAYAWTDLALCRAGATTVFELAAAGVPAVFVPFPFATHDHQTANAAFLADRGAAQSIAQRDLESMPPAVLAGQ
IIDLLKDHGRLQGMSAAMRRMARPEAAAAIVSGAKDLIRKKPLRSLVPEREGE
>Mature_373_residues
MKRVLLTTGGTGGHIFPALAVAEEIRRQYPAADILFVGGSYGPEARIVPAHGIRFEGLPVRGVMGRGLKAPLALAAMTAG
VARGMRLVGRFNPDVVIGFGGYAAFAAMVAAKLREKPCAVHEQNSVPGMANRLLAKIADRVFISFPDPQEYFLQRKTVLT
GNPVRAAIAAAGAHRAGHVPACRLLVMGGSQGAHALNLAVVNMLPQLRDAGVEILHQTGAADLETVRSAYDKAGVQATVV
DFVEDMAAAYAWTDLALCRAGATTVFELAAAGVPAVFVPFPFATHDHQTANAAFLADRGAAQSIAQRDLESMPPAVLAGQ
IIDLLKDHGRLQGMSAAMRRMARPEAAAAIVSGAKDLIRKKPLRSLVPEREGE

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=314, Percent_Identity=40.7643312101911, Blast_Score=199, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_DESDG (Q313Q3)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_387538.1
- ProteinModelPortal:   Q313Q3
- SMR:   Q313Q3
- STRING:   Q313Q3
- GeneID:   3755467
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_1042
- NMPDR:   fig|207559.3.peg.871
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- BioCyc:   DDES207559:DDE_1042-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39286; Mature: 39286

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLLTTGGTGGHIFPALAVAEEIRRQYPAADILFVGGSYGPEARIVPAHGIRFEGLPV
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEECCCCC
RGVMGRGLKAPLALAAMTAGVARGMRLVGRFNPDVVIGFGGYAAFAAMVAAKLREKPCAV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCC
HEQNSVPGMANRLLAKIADRVFISFPDPQEYFLQRKTVLTGNPVRAAIAAAGAHRAGHVP
CCCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHEECCCCHHHHHHHHCCCCCCCCC
ACRLLVMGGSQGAHALNLAVVNMLPQLRDAGVEILHQTGAADLETVRSAYDKAGVQATVV
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
DFVEDMAAAYAWTDLALCRAGATTVFELAAAGVPAVFVPFPFATHDHQTANAAFLADRGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCHH
AQSIAQRDLESMPPAVLAGQIIDLLKDHGRLQGMSAAMRRMARPEAAAAIVSGAKDLIRK
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KPLRSLVPEREGE
CHHHHHCCCCCCC
>Mature Secondary Structure
MKRVLLTTGGTGGHIFPALAVAEEIRRQYPAADILFVGGSYGPEARIVPAHGIRFEGLPV
CCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCCEECCCCC
RGVMGRGLKAPLALAAMTAGVARGMRLVGRFNPDVVIGFGGYAAFAAMVAAKLREKPCAV
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHCCCCCC
HEQNSVPGMANRLLAKIADRVFISFPDPQEYFLQRKTVLTGNPVRAAIAAAGAHRAGHVP
CCCCCCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHEECCCCHHHHHHHHCCCCCCCCC
ACRLLVMGGSQGAHALNLAVVNMLPQLRDAGVEILHQTGAADLETVRSAYDKAGVQATVV
EEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHH
DFVEDMAAAYAWTDLALCRAGATTVFELAAAGVPAVFVPFPFATHDHQTANAAFLADRGA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHCCHH
AQSIAQRDLESMPPAVLAGQIIDLLKDHGRLQGMSAAMRRMARPEAAAAIVSGAKDLIRK
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KPLRSLVPEREGE
CHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA