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The map label for this gene is 78356025

Identifier: 78356025

GI number: 78356025

Start: 1005754

End: 1007337

Strand: Reverse

Name: 78356025

Synonym: Dde_0978

Alternate gene names: NA

Gene position: 1007337-1005754 (Counterclockwise)

Preceding gene: 78356026

Following gene: 78356023

Centisome position: 27.0

GC content: 55.3

Gene sequence:

>1584_bases
ATGACAATAAAAGGGAGTCGAGGCATGGGCCTTATAGAAATAGTACTCCTCCTCGTCGGCATGGCAGTCGGGGCAGCCAC
AGGCTTCATACTGCACAAAATAGTCAGCGCCAAACGTCTGCAGGACGCCCGCGAACTGGCCGACCGCATTATCGAGGAGG
CACGCAAAGAGGCACAGGCGCACAAAAAGGAAGTGCTCATCCAGGGGCAGGATGAACTCTTTAACCAGAAACGTGAACTC
GAACGCGAATTTAAAGAACGCGAACACGAACTGAAAATCCGTGAACGCAGGCTGCAGGAACAGACCGAACGGCTTGAAGA
AAAACTGGAAAAGCTGGCCCAGAAAGAACACGATGCTCTTTCTGTGGAAAAAGAACTGAACAGGCGCGAACGCACTCTGG
GGCTTAAGGAAGAGGAACTGACCCAGAAAATTGCGGAGCAGGATAAAAAGCTTCAGGAAATATCCGGTCTGACATCTGAA
GAAGCCAAGGCGCGCATTTTCAGCGAAGTGGAGGCAAGAACCCGCCACGAAGCCGGAAAGATGATCCGCGTCATAGAAAC
AGAAGCCAAGGAGACCGCTTCGCGCAGTGCCCAGAAAATTCTGGCCACAGCTGTTCAGCGGTATGCCGGCGACTTTGTCA
ACGAACAGACCGTTACCGCAGTCTCGCTGCCCAGCGAAGACATGAAAGGCCGCATCATAGGCCGCGAAGGACGCAACATC
CGTGCGCTGGAAGCAGCCACCGGCGTTGATCTGATCATTGACGACACTCCGGAAACGGTCATCCTTTCCGCCTACAGCCC
TCTGCGCAGGCAGATTGCCAAAATGGCACTGGAAAGGCTGATCAGCGACGGACGTATCCACCCCGCACGCATTGAAGACA
TTGTACGCAAGTGTGAGCAGGAGCTGGAAGTGCAGCTGCGCGAAGTGGGCGAACAGGCTACCTTTGACGTGGGCGTGCAC
GGCATACATCCCGAAATCATCAAACTGCTGGGGCAGCTCAAATACCGCACCAGCTTTTCGCAGAATGTGCTTCAGCACTC
CATGGAAGTCGCATCGCTGTGCGGCATTATGGCTGCAGAACTGGGCATGGACGAAAAACGCGCCAAGCGCGCGGGGCTGC
TGCACGACATCGGCAAAGCAGTGGACCACGATGTGGAAGGTCCGCATGCCGTCATCGGAGCCGATCTGGCAAAGAAATAC
GGCGAATCCAAGGACATTATCCACGCCATAGCAGCCCACCACGAAGATGTGCCGCCCAAAAGCGCTCTGGCTGTGCTGGT
GCAGGCCGCAGACAGCCTTTCCGGTGCACGCCCCGGTGCGCGCAAGGAATTGCTGGAAAATTACGTGAAGCGGCTTGAAG
ACCTTGAAGGTATAGCCAACGGCATGGAAGGGGTTTCCAAAGCCTACGCCATTCAGGCAGGCCGCGAAATCCGCGTTCTT
GTCAATTCCGATGAAGTTGACGACGACACAACATACATGCTGTGCAAAGACATCTCGGAAAAAATCGAGAAAAACCTCAC
CTATCCCGGCCAGATCCGCGTTACCGTCATCCGGGAACGCCGCGCCGTGGGTGTGGCCAAATAG

Upstream 100 bases:

>100_bases
GGCAGTAAAGCAACCTTTCCTGCTTGCCCGCTTCCCTTTATGGAACCGGCCGGTCAGCGTGACCGCCGTCGGGATTCATT
CAACCGGGTCAACGCACCCG

Downstream 100 bases:

>100_bases
CAGCCGGAACAACCGCTCTGCATACAAAACGCCCGCATCGGCAGATGCGGGCGTTTTTACTTTTCTCCGCCGGTAATTTT
GCCGGTGCCTGCCGCAGGGC

Product: phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MTIKGSRGMGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQAHKKEVLIQGQDELFNQKREL
EREFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDALSVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSE
EAKARIFSEVEARTRHEAGKMIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNI
RALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQELEVQLREVGEQATFDVGVH
GIHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAELGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKY
GESKDIIHAIAAHHEDVPPKSALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVL
VNSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK

Sequences:

>Translated_527_residues
MTIKGSRGMGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQAHKKEVLIQGQDELFNQKREL
EREFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDALSVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSE
EAKARIFSEVEARTRHEAGKMIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNI
RALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQELEVQLREVGEQATFDVGVH
GIHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAELGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKY
GESKDIIHAIAAHHEDVPPKSALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVL
VNSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK
>Mature_526_residues
TIKGSRGMGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQAHKKEVLIQGQDELFNQKRELE
REFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDALSVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSEE
AKARIFSEVEARTRHEAGKMIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNIR
ALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQELEVQLREVGEQATFDVGVHG
IHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAELGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKYG
ESKDIIHAIAAHHEDVPPKSALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVLV
NSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK

Specific function: Catalyzes the hydrolysis of both 2',3'-cyclic AMP and 2',3'-cyclic GMP into 3'-AMP and 3'-GMP, respectively, at the 3'- terminal of RNA [H]

COG id: COG1418

COG function: function code R; Predicted HD superfamily hydrolase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017705
- InterPro:   IPR022711
- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR003607
- InterPro:   IPR006675 [H]

Pfam domain/function: PF12072 DUF3552; PF00013 KH_1 [H]

EC number: =3.1.4.16 [H]

Molecular weight: Translated: 58948; Mature: 58817

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: PS50084 KH_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKGSRGMGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKKEVLIQGQDELFNQKRELEREFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSEEAKARIFSEVEARTRHEAGK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCE
RALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQ
EEEHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ELEVQLREVGEQATFDVGVHGIHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAE
HHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKYGESKDIIHAIAAHHEDVPPK
HCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCH
SALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VNSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHCCCCC
>Mature Secondary Structure 
TIKGSRGMGLIEIVLLLVGMAVGAATGFILHKIVSAKRLQDARELADRIIEEARKEAQA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HKKEVLIQGQDELFNQKRELEREFKEREHELKIRERRLQEQTERLEEKLEKLAQKEHDAL
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVEKELNRRERTLGLKEEELTQKIAEQDKKLQEISGLTSEEAKARIFSEVEARTRHEAGK
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MIRVIETEAKETASRSAQKILATAVQRYAGDFVNEQTVTAVSLPSEDMKGRIIGREGRNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEECCCCCCE
RALEAATGVDLIIDDTPETVILSAYSPLRRQIAKMALERLISDGRIHPARIEDIVRKCEQ
EEEHHHCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ELEVQLREVGEQATFDVGVHGIHPEIIKLLGQLKYRTSFSQNVLQHSMEVASLCGIMAAE
HHHHHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGMDEKRAKRAGLLHDIGKAVDHDVEGPHAVIGADLAKKYGESKDIIHAIAAHHEDVPPK
HCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCH
SALAVLVQAADSLSGARPGARKELLENYVKRLEDLEGIANGMEGVSKAYAIQAGREIRVL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
VNSDEVDDDTTYMLCKDISEKIEKNLTYPGQIRVTVIRERRAVGVAK
ECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA