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The map label for this gene is glmS [H]

Identifier: 78356005

GI number: 78356005

Start: 982896

End: 983693

Strand: Direct

Name: glmS [H]

Synonym: Dde_0958

Alternate gene names: 78356005

Gene position: 982896-983693 (Clockwise)

Preceding gene: 78356004

Following gene: 78356006

Centisome position: 26.35

GC content: 65.04

Gene sequence:

>798_bases
ATGTGCGGACAAGTAGGCATCATCTTCGGCCGCAAGCGCAGACGGCCGGACGAGCAGGATTACCTGCGCGAGGTCTTCAT
CCGCATGCTGCTGCACAGCGAGGAGCGCGGCCCGCACGCCTCCGGTCTGGCCTGGCTCAAGATCGACGGCAGCCACCGGA
TCTTCAAGCGGCCGATGCGGGCGCACGAACTGGTCTACGAGAAGCCGTTCCAGGAGCTGCTCGGGCAGGTCGACAACGAG
ACCACCATCCTCATGGGCCACACCCGCTGGCGCACCCGGGGCAACGAGTTCAACAACCGCAACAACCATCCCATCCGGGC
CGGGATCGTCATCGGTACCCACAACGGCACCATCTACAACGCCGATTATCTGTTCCGCCGTCTCGGGCTGCCGCGCTTCG
CCGAAGTGGACAGCGAGCTGATCTTCCGCCTGGCCGACCGCTTCGCGCCCGAAGGCCCCATCGACCAGGAGGGCCTGAAG
AAGGCGCTCGCCCTCTGTCGCGGCCAGATGAGCGCCGTGCTGGCCTCGCGGCTCGACCCCGGCACCATCACCGTGCTCAA
GGGCAACAAACCGCTCTGCCTGCGCATCCACCGCCAGCACCGGGTGGTGCTCTACGCCTCGGAGCCAGCCTTCATCGACT
TTGCCGTGGACTTTGATCCGGGCTGGCGCGAGCTGGAGGTGCCGCCCATGACCATGCTCACCATCCGCCACAAGGATGTG
CGGGCCATCGAAAACAGCGAATTCCGCTTCATACCCCAGGAGCGCAAAGGGACACTGCCCGAAGGAGTGAATGCATGA

Upstream 100 bases:

>100_bases
CCGAGTGGCTGACGGGCCACCGGCGCGAGTACGCGGCCTTCGTCCTCGATGGGACAAGACCGCTCGGCAAGAACTTCGGC
GGCAAGGAGGACCCGGCTCC

Downstream 100 bases:

>100_bases
ACATTGGAGAACCATCAAAGCTGAACACAAATCCGGAAGACAGTCCCGAGACCATCCTCCGGCTCTTCGTCTACGGCACC
CTGAAACGGGGCTATTGGAA

Product: glucosamine 6-phosphate synthetase-like

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MCGQVGIIFGRKRRRPDEQDYLREVFIRMLLHSEERGPHASGLAWLKIDGSHRIFKRPMRAHELVYEKPFQELLGQVDNE
TTILMGHTRWRTRGNEFNNRNNHPIRAGIVIGTHNGTIYNADYLFRRLGLPRFAEVDSELIFRLADRFAPEGPIDQEGLK
KALALCRGQMSAVLASRLDPGTITVLKGNKPLCLRIHRQHRVVLYASEPAFIDFAVDFDPGWRELEVPPMTMLTIRHKDV
RAIENSEFRFIPQERKGTLPEGVNA

Sequences:

>Translated_265_residues
MCGQVGIIFGRKRRRPDEQDYLREVFIRMLLHSEERGPHASGLAWLKIDGSHRIFKRPMRAHELVYEKPFQELLGQVDNE
TTILMGHTRWRTRGNEFNNRNNHPIRAGIVIGTHNGTIYNADYLFRRLGLPRFAEVDSELIFRLADRFAPEGPIDQEGLK
KALALCRGQMSAVLASRLDPGTITVLKGNKPLCLRIHRQHRVVLYASEPAFIDFAVDFDPGWRELEVPPMTMLTIRHKDV
RAIENSEFRFIPQERKGTLPEGVNA
>Mature_265_residues
MCGQVGIIFGRKRRRPDEQDYLREVFIRMLLHSEERGPHASGLAWLKIDGSHRIFKRPMRAHELVYEKPFQELLGQVDNE
TTILMGHTRWRTRGNEFNNRNNHPIRAGIVIGTHNGTIYNADYLFRRLGLPRFAEVDSELIFRLADRFAPEGPIDQEGLK
KALALCRGQMSAVLASRLDPGTITVLKGNKPLCLRIHRQHRVVLYASEPAFIDFAVDFDPGWRELEVPPMTMLTIRHKDV
RAIENSEFRFIPQERKGTLPEGVNA

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 30515; Mature: 30515

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGQVGIIFGRKRRRPDEQDYLREVFIRMLLHSEERGPHASGLAWLKIDGSHRIFKRPMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHH
AHELVYEKPFQELLGQVDNETTILMGHTRWRTRGNEFNNRNNHPIRAGIVIGTHNGTIYN
HHHHHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCCCCCCCEEEEEEEECCCCEEEE
ADYLFRRLGLPRFAEVDSELIFRLADRFAPEGPIDQEGLKKALALCRGQMSAVLASRLDP
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GTITVLKGNKPLCLRIHRQHRVVLYASEPAFIDFAVDFDPGWRELEVPPMTMLTIRHKDV
CEEEEEECCCCEEEEEECCCEEEEEECCCCEEEEEEECCCCCCEECCCCEEEEEEECCHH
RAIENSEFRFIPQERKGTLPEGVNA
HHHCCCCEEECCHHHCCCCCCCCCC
>Mature Secondary Structure
MCGQVGIIFGRKRRRPDEQDYLREVFIRMLLHSEERGPHASGLAWLKIDGSHRIFKRPMR
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHH
AHELVYEKPFQELLGQVDNETTILMGHTRWRTRGNEFNNRNNHPIRAGIVIGTHNGTIYN
HHHHHHHHHHHHHHHCCCCCEEEEEECCEECCCCCCCCCCCCCCEEEEEEEECCCCEEEE
ADYLFRRLGLPRFAEVDSELIFRLADRFAPEGPIDQEGLKKALALCRGQMSAVLASRLDP
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GTITVLKGNKPLCLRIHRQHRVVLYASEPAFIDFAVDFDPGWRELEVPPMTMLTIRHKDV
CEEEEEECCCCEEEEEECCCEEEEEECCCCEEEEEEECCCCCCEECCCCEEEEEEECCHH
RAIENSEFRFIPQERKGTLPEGVNA
HHHCCCCEEECCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]