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The map label for this gene is ydfD [H]

Identifier: 78355668

GI number: 78355668

Start: 640922

End: 642565

Strand: Reverse

Name: ydfD [H]

Synonym: Dde_0621

Alternate gene names: 78355668

Gene position: 642565-640922 (Counterclockwise)

Preceding gene: 78355673

Following gene: 78355665

Centisome position: 17.23

GC content: 60.16

Gene sequence:

>1644_bases
ATGCATCCTCGATCAACAAAAAATGAAGCATGCCTCTACGCCTGCATTGACCCCTTGATAAGGGACACTTTTTATGAATA
TTTACAGGGTCACTTTAACGACGTCATCCTCTGTTCCGCACCGCCGGACGCAGCCGTCTTTCCGGAGGCTTTCATGAGTA
TTCCGCTGAACCACAACACCCCGCTGCCGCTGTATAAACAGCTTGCGGCCTACCTGCGTCAGCGCATCGAACTGGGTGAA
CTGGAACCGGGCACAAAACTGCCGTCCATCCGCCATATGGCCCGCAGTCAGGGTATCAACCGCATTACCGTGGAAACCGC
CTATGCCGAACTGGAAGCTGACGGGCTGGTGACATCGCGCAGGGGCAGCGGCACTTTTGTGCTACCGCCTTTTCCCGGCC
ACGACGGCCCGCAGGCCGATACACCCGGCAGATGGCCCGCATGGCAGCACGCAGCAGCCGAACGCTTCGAGGCCATATGG
CCCGGACACCCCGCCCCGCTGCACAGCGGAGCAACTCCTGCGGGGGTGATCTCGCTGGCAGACGGCAACAGCGACCCCCT
GCTTTTCCCCTTCGAAGCTTTCAGCCGGACCCTGCGCGAGGTCATGCGCCGCGACGGCACCGCCGCGCTGGAATACGAGG
AAGCCGCAGGTTACCGTCCGCTGCGCCGGACCATCGCCCGCATTCTTGTCGATCAGGGCATAGGTGTGACGCCTGACAAC
ATTGTGGTCACATCCGGCTCGCAGCAGGCCATTTTCATCATCGCGCAGGTGCTGCTGCGCAAAGGGCAGACCGTCTACAC
CGAAACCCCCACCTATCCCGAGTCACTCAGGCTTTTCCGCACCATGGGCATGCGCATAGCCGCCATACCCATGGACAGCG
GCGGCATGCGCACCGACCTGCTGGAACAGGCCATGCGCACACACGGCGAAGGGCTGATTCTGACCATGCCCACGTTTCAC
AACCCTACGGGCATCTGCATGGACGGACACCGCCGGCGTATTCTTGCCTCCATGGCAGAAGCGCATGGCATTGCGGTGGT
GGAAGACGACTACGCCGGCGATATCCGCTATGAAGGGCATTCGCAACCGGCCATCAAAAGTCTGAGTGCCGCAGGCAACT
GCCTGTACATCGGCACGTTTTCAAAAATGCTCGTACCCGGCCTGCGGGTGGGCTACATTGTTGCCGAAGGGCCGGTGCTG
ACACAACTTGAACGCTATAAACGCATGCTTGATCTTTCTTCGCCCGGACTTGTGCAGCGGGTGCTGGAACGATTCGTTGA
TGTGGGCAGCTACCGCAACCACCTGAACAGACTGTGCCGCACCTACCGCATGCGGCGCGACATAATGCTGGACTGTGCGC
AAAAATGGCTGCCCCGATGCGTGCATATCACCCCGCCGTCCGGCGGGCTGTTTGCCTGGCTGCGGCTGCCGGAAGACGTG
CATGCCGACGCCCTTGCCGAAACGGCCCCCCACCACGGGGTGGCTATTGCCAGCGGCACGGCTTTTTTTCCTCAGCCTCA
GGAAGGCGCCCGCCATATCCGCATAAATTTTTGCAGACACGACGAGAACACCCTGAAAGAAGCCATGCGCAGGCTTGGAA
CAGCCATGCAGAAAAGCATCGCCGCCACAAAGTATATGAAGTGA

Upstream 100 bases:

>100_bases
CAGCGGCCACAAGAGCCGAAAGATACCCGGCCGAAGCGCCGGAAAACCGCAGTCCGTTCAGGGGGCTGCGCAACGAAAAA
GACATGGTGTTCTGCATGGC

Downstream 100 bases:

>100_bases
TAACATGCTTGTTTTTATAAACATACCGGACTGCTTCATAAAAAAATAAAAAAAATGAAATTTGTCCGTTGACAACAGAC
CCCTGTCTCTATACAAAGGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MHPRSTKNEACLYACIDPLIRDTFYEYLQGHFNDVILCSAPPDAAVFPEAFMSIPLNHNTPLPLYKQLAAYLRQRIELGE
LEPGTKLPSIRHMARSQGINRITVETAYAELEADGLVTSRRGSGTFVLPPFPGHDGPQADTPGRWPAWQHAAAERFEAIW
PGHPAPLHSGATPAGVISLADGNSDPLLFPFEAFSRTLREVMRRDGTAALEYEEAAGYRPLRRTIARILVDQGIGVTPDN
IVVTSGSQQAIFIIAQVLLRKGQTVYTETPTYPESLRLFRTMGMRIAAIPMDSGGMRTDLLEQAMRTHGEGLILTMPTFH
NPTGICMDGHRRRILASMAEAHGIAVVEDDYAGDIRYEGHSQPAIKSLSAAGNCLYIGTFSKMLVPGLRVGYIVAEGPVL
TQLERYKRMLDLSSPGLVQRVLERFVDVGSYRNHLNRLCRTYRMRRDIMLDCAQKWLPRCVHITPPSGGLFAWLRLPEDV
HADALAETAPHHGVAIASGTAFFPQPQEGARHIRINFCRHDENTLKEAMRRLGTAMQKSIAATKYMK

Sequences:

>Translated_547_residues
MHPRSTKNEACLYACIDPLIRDTFYEYLQGHFNDVILCSAPPDAAVFPEAFMSIPLNHNTPLPLYKQLAAYLRQRIELGE
LEPGTKLPSIRHMARSQGINRITVETAYAELEADGLVTSRRGSGTFVLPPFPGHDGPQADTPGRWPAWQHAAAERFEAIW
PGHPAPLHSGATPAGVISLADGNSDPLLFPFEAFSRTLREVMRRDGTAALEYEEAAGYRPLRRTIARILVDQGIGVTPDN
IVVTSGSQQAIFIIAQVLLRKGQTVYTETPTYPESLRLFRTMGMRIAAIPMDSGGMRTDLLEQAMRTHGEGLILTMPTFH
NPTGICMDGHRRRILASMAEAHGIAVVEDDYAGDIRYEGHSQPAIKSLSAAGNCLYIGTFSKMLVPGLRVGYIVAEGPVL
TQLERYKRMLDLSSPGLVQRVLERFVDVGSYRNHLNRLCRTYRMRRDIMLDCAQKWLPRCVHITPPSGGLFAWLRLPEDV
HADALAETAPHHGVAIASGTAFFPQPQEGARHIRINFCRHDENTLKEAMRRLGTAMQKSIAATKYMK
>Mature_547_residues
MHPRSTKNEACLYACIDPLIRDTFYEYLQGHFNDVILCSAPPDAAVFPEAFMSIPLNHNTPLPLYKQLAAYLRQRIELGE
LEPGTKLPSIRHMARSQGINRITVETAYAELEADGLVTSRRGSGTFVLPPFPGHDGPQADTPGRWPAWQHAAAERFEAIW
PGHPAPLHSGATPAGVISLADGNSDPLLFPFEAFSRTLREVMRRDGTAALEYEEAAGYRPLRRTIARILVDQGIGVTPDN
IVVTSGSQQAIFIIAQVLLRKGQTVYTETPTYPESLRLFRTMGMRIAAIPMDSGGMRTDLLEQAMRTHGEGLILTMPTFH
NPTGICMDGHRRRILASMAEAHGIAVVEDDYAGDIRYEGHSQPAIKSLSAAGNCLYIGTFSKMLVPGLRVGYIVAEGPVL
TQLERYKRMLDLSSPGLVQRVLERFVDVGSYRNHLNRLCRTYRMRRDIMLDCAQKWLPRCVHITPPSGGLFAWLRLPEDV
HADALAETAPHHGVAIASGTAFFPQPQEGARHIRINFCRHDENTLKEAMRRLGTAMQKSIAATKYMK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=402, Percent_Identity=22.8855721393035, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI33469970, Length=402, Percent_Identity=22.8855721393035, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1790797, Length=482, Percent_Identity=29.6680497925311, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1787710, Length=479, Percent_Identity=27.9749478079332, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1788722, Length=332, Percent_Identity=23.1927710843373, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321236, Length=402, Percent_Identity=23.6318407960199, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356535, Length=378, Percent_Identity=24.8677248677249, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 60740; Mature: 60740

Theoretical pI: Translated: 8.18; Mature: 8.18

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPRSTKNEACLYACIDPLIRDTFYEYLQGHFNDVILCSAPPDAAVFPEAFMSIPLNHNT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHCCCCCCCC
PLPLYKQLAAYLRQRIELGELEPGTKLPSIRHMARSQGINRITVETAYAELEADGLVTSR
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCCEEEC
RGSGTFVLPPFPGHDGPQADTPGRWPAWQHAAAERFEAIWPGHPAPLHSGATPAGVISLA
CCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
DGNSDPLLFPFEAFSRTLREVMRRDGTAALEYEEAAGYRPLRRTIARILVDQGIGVTPDN
CCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCC
IVVTSGSQQAIFIIAQVLLRKGQTVYTETPTYPESLRLFRTMGMRIAAIPMDSGGMRTDL
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHH
LEQAMRTHGEGLILTMPTFHNPTGICMDGHRRRILASMAEAHGIAVVEDDYAGDIRYEGH
HHHHHHHCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHCCEEEEECCCCCCEEECCC
SQPAIKSLSAAGNCLYIGTFSKMLVPGLRVGYIVAEGPVLTQLERYKRMLDLSSPGLVQR
CCHHHHHHHCCCCEEEEECHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHH
VLERFVDVGSYRNHLNRLCRTYRMRRDIMLDCAQKWLPRCVHITPPSGGLFAWLRLPEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCHH
HADALAETAPHHGVAIASGTAFFPQPQEGARHIRINFCRHDENTLKEAMRRLGTAMQKSI
HHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
AATKYMK
HHHHCCC
>Mature Secondary Structure
MHPRSTKNEACLYACIDPLIRDTFYEYLQGHFNDVILCSAPPDAAVFPEAFMSIPLNHNT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHCCCCCCCC
PLPLYKQLAAYLRQRIELGELEPGTKLPSIRHMARSQGINRITVETAYAELEADGLVTSR
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEHHHHHCCCCCEEEC
RGSGTFVLPPFPGHDGPQADTPGRWPAWQHAAAERFEAIWPGHPAPLHSGATPAGVISLA
CCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEE
DGNSDPLLFPFEAFSRTLREVMRRDGTAALEYEEAAGYRPLRRTIARILVDQGIGVTPDN
CCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHHHCCCCCCCCC
IVVTSGSQQAIFIIAQVLLRKGQTVYTETPTYPESLRLFRTMGMRIAAIPMDSGGMRTDL
EEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHH
LEQAMRTHGEGLILTMPTFHNPTGICMDGHRRRILASMAEAHGIAVVEDDYAGDIRYEGH
HHHHHHHCCCEEEEECCCCCCCCCEEECCHHHHHHHHHHHHCCEEEEECCCCCCEEECCC
SQPAIKSLSAAGNCLYIGTFSKMLVPGLRVGYIVAEGPVLTQLERYKRMLDLSSPGLVQR
CCHHHHHHHCCCCEEEEECHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHCCCCCHHHHH
VLERFVDVGSYRNHLNRLCRTYRMRRDIMLDCAQKWLPRCVHITPPSGGLFAWLRLPEDV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCHH
HADALAETAPHHGVAIASGTAFFPQPQEGARHIRINFCRHDENTLKEAMRRLGTAMQKSI
HHHHHHHCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHH
AATKYMK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]