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The map label for this gene is mdtE [H]

Identifier: 78355596

GI number: 78355596

Start: 567933

End: 569156

Strand: Reverse

Name: mdtE [H]

Synonym: Dde_0549

Alternate gene names: 78355596

Gene position: 569156-567933 (Counterclockwise)

Preceding gene: 78355599

Following gene: 78355595

Centisome position: 15.26

GC content: 61.76

Gene sequence:

>1224_bases
ATGCGCACCAGAACGCTTCTGACAGCCGCTGCAGGCATCGCAGTACTGGCGGTTATTTTCATGTGGTCTGCCAATATGCT
GAATACACAACGCATCAGCCCGGAAGACACATTTTCATCCCCCCGTCTGCCTGCGGGCAACATTACAGTAAACACGATTA
CGGCTGCTGCCGTGCCCGTGACAGATACGGCGGAAGCCACCGGCACAGTGCGTCCGCGCACCGAGACCCGCGTGGAAGCG
CAGGTCACCGCAAAAATTCTGCGTATGGCCGTTACCACCGGCGATGTGGTAAAAAAAGGAGACGTACTGGTAGAGCTGGA
TGCCCGAGAGCTTGTATCGCGGCGGGATCAGGCGGGGCAGGCGCTGATAAGCAGCAGGGCAGCACTGGGGCAGGCGCGCC
AGTCCGTGGCCGAAGCCAGAGCCGCCTTTGATAAAACCCGCAACCAGTACAGACGCATCAAGGCGCTGTTTTCCGAAAGA
GCTGTTGCCCAGCGCGAACTTGATCAGGCGGAAGCGGATTATCTGCAGGCGGAAGCTGCTCTGGGCAGTGCGCGCGGAGG
TCTGAGCGGGGCGGAATCTGCCGTGCAGCAGGCGCAGAAAAGACTGGAAGAAGCTGAAATAGCTCTTGGTTATGCCACCA
TCACCGCGCTGGAGGACGGCGAGATAGTCCGGCGTGAGGCCGAAGCCGGCGATCTGGCTTTTCCCGGCAAACCTCTGCTG
GTGGTACAGGCAGGCGGAGCACTGCGGCTGGAAGCACAGGTCCGTGAAGGACTTATAGGACGCGTGCGCCCCGGAGTGCG
TCTGCAGGTGAACATTTCTGCGCTGGGCACAGACACGCTGGACGGCGTGGTGGAAGAGGTGGTGCCCTCGGCAGACCCGC
GCACACGAACCTTTCTGGTCAAGGTGGGGCTGCCGCCCGCCCCCGGACTGTACCCCGGCATGTACGGCACGCTGCTCATT
CCGCTTGATGCGCAGACTGCCGTTCTTGTGCCTGCTGCGGCGGTGCACCGTGTGGGGCAGCTCGAAACAGTGAGCATCCT
GTCAGATGAAGGCATCCCGCACACCGTGCATGTGAAAACGGGCAGACATTTCGGCCAGCAGGTGGAAATACTCTCGGGTC
TTTCAGGCGGCGAGACTCTTGTGCTGCCCGCAGGCGGGGCACAGACCCCACCGGAACGCACACCGCAGGAAGCAGCCGCA
GGAGACAGCCATGCCGCAGCATGA

Upstream 100 bases:

>100_bases
AACACTATATCAGGTACTGTTCTGCAAAGCCGGCATCGAAAAACAAGCCGTATGCTTAATACAATCCACGCCGGACGACA
ACAGCTCCGCGGAGACACCC

Downstream 100 bases:

>100_bases
CGCCGCACCGGCAGGAATAATTCCCGCCATTGTCCGCACATTTGTCACCGGCAAAAATGCTCTGCTGCTGCTCATTTTCG
GTCTCGGGCTGGGCATGGCC

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRTRTLLTAAAGIAVLAVIFMWSANMLNTQRISPEDTFSSPRLPAGNITVNTITAAAVPVTDTAEATGTVRPRTETRVEA
QVTAKILRMAVTTGDVVKKGDVLVELDARELVSRRDQAGQALISSRAALGQARQSVAEARAAFDKTRNQYRRIKALFSER
AVAQRELDQAEADYLQAEAALGSARGGLSGAESAVQQAQKRLEEAEIALGYATITALEDGEIVRREAEAGDLAFPGKPLL
VVQAGGALRLEAQVREGLIGRVRPGVRLQVNISALGTDTLDGVVEEVVPSADPRTRTFLVKVGLPPAPGLYPGMYGTLLI
PLDAQTAVLVPAAAVHRVGQLETVSILSDEGIPHTVHVKTGRHFGQQVEILSGLSGGETLVLPAGGAQTPPERTPQEAAA
GDSHAAA

Sequences:

>Translated_407_residues
MRTRTLLTAAAGIAVLAVIFMWSANMLNTQRISPEDTFSSPRLPAGNITVNTITAAAVPVTDTAEATGTVRPRTETRVEA
QVTAKILRMAVTTGDVVKKGDVLVELDARELVSRRDQAGQALISSRAALGQARQSVAEARAAFDKTRNQYRRIKALFSER
AVAQRELDQAEADYLQAEAALGSARGGLSGAESAVQQAQKRLEEAEIALGYATITALEDGEIVRREAEAGDLAFPGKPLL
VVQAGGALRLEAQVREGLIGRVRPGVRLQVNISALGTDTLDGVVEEVVPSADPRTRTFLVKVGLPPAPGLYPGMYGTLLI
PLDAQTAVLVPAAAVHRVGQLETVSILSDEGIPHTVHVKTGRHFGQQVEILSGLSGGETLVLPAGGAQTPPERTPQEAAA
GDSHAAA
>Mature_407_residues
MRTRTLLTAAAGIAVLAVIFMWSANMLNTQRISPEDTFSSPRLPAGNITVNTITAAAVPVTDTAEATGTVRPRTETRVEA
QVTAKILRMAVTTGDVVKKGDVLVELDARELVSRRDQAGQALISSRAALGQARQSVAEARAAFDKTRNQYRRIKALFSER
AVAQRELDQAEADYLQAEAALGSARGGLSGAESAVQQAQKRLEEAEIALGYATITALEDGEIVRREAEAGDLAFPGKPLL
VVQAGGALRLEAQVREGLIGRVRPGVRLQVNISALGTDTLDGVVEEVVPSADPRTRTFLVKVGLPPAPGLYPGMYGTLLI
PLDAQTAVLVPAAAVHRVGQLETVSILSDEGIPHTVHVKTGRHFGQQVEILSGLSGGETLVLPAGGAQTPPERTPQEAAA
GDSHAAA

Specific function: Part of a multidrug resistance efflux system that confers resistance to compounds such as rhodamine 6G, erythromycin, doxorubicin, ethidium bromide, TPP, SDS, deoxycholate, crystal violet and benzalkonium [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789929, Length=350, Percent_Identity=24.2857142857143, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42795; Mature: 42795

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRTLLTAAAGIAVLAVIFMWSANMLNTQRISPEDTFSSPRLPAGNITVNTITAAAVPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECC
TDTAEATGTVRPRTETRVEAQVTAKILRMAVTTGDVVKKGDVLVELDARELVSRRDQAGQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEECHHHHHHHHHHHHH
ALISSRAALGQARQSVAEARAAFDKTRNQYRRIKALFSERAVAQRELDQAEADYLQAEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSARGGLSGAESAVQQAQKRLEEAEIALGYATITALEDGEIVRREAEAGDLAFPGKPLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHHCCCCCCCCCCCCEE
VVQAGGALRLEAQVREGLIGRVRPGVRLQVNISALGTDTLDGVVEEVVPSADPRTRTFLV
EEECCCCEEEHHHHHCCHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEE
KVGLPPAPGLYPGMYGTLLIPLDAQTAVLVPAAAVHRVGQLETVSILSDEGIPHTVHVKT
EECCCCCCCCCCCCCCEEEEEECCCCEEEECHHHHHHCCCCEEEEEECCCCCCEEEEEEC
GRHFGQQVEILSGLSGGETLVLPAGGAQTPPERTPQEAAAGDSHAAA
CCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MRTRTLLTAAAGIAVLAVIFMWSANMLNTQRISPEDTFSSPRLPAGNITVNTITAAAVPV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECC
TDTAEATGTVRPRTETRVEAQVTAKILRMAVTTGDVVKKGDVLVELDARELVSRRDQAGQ
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCEEEEECHHHHHHHHHHHHH
ALISSRAALGQARQSVAEARAAFDKTRNQYRRIKALFSERAVAQRELDQAEADYLQAEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSARGGLSGAESAVQQAQKRLEEAEIALGYATITALEDGEIVRREAEAGDLAFPGKPLL
HHHCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCHHHHHHCCCCCCCCCCCCEE
VVQAGGALRLEAQVREGLIGRVRPGVRLQVNISALGTDTLDGVVEEVVPSADPRTRTFLV
EEECCCCEEEHHHHHCCHHHHCCCCEEEEEEEEECCCHHHHHHHHHHCCCCCCCCEEEEE
KVGLPPAPGLYPGMYGTLLIPLDAQTAVLVPAAAVHRVGQLETVSILSDEGIPHTVHVKT
EECCCCCCCCCCCCCCEEEEEECCCCEEEECHHHHHHCCCCEEEEEECCCCCCEEEEEEC
GRHFGQQVEILSGLSGGETLVLPAGGAQTPPERTPQEAAAGDSHAAA
CCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]