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The map label for this gene is luxQ [H]

Identifier: 78355580

GI number: 78355580

Start: 540854

End: 541588

Strand: Reverse

Name: luxQ [H]

Synonym: Dde_0533

Alternate gene names: 78355580

Gene position: 541588-540854 (Counterclockwise)

Preceding gene: 78355582

Following gene: 78355577

Centisome position: 14.52

GC content: 58.5

Gene sequence:

>735_bases
GTGTATCCGGACAAAAACGACGTCATCTGCTTTGACGTGTGCGATACCGGACCGGGTATACCGCACAGCAAGCGCCATCT
GCTTTTTGAAAGCTTTGTACAGCTTGATGGCTCGCTTTCGCGCCAGCATCAAGGCAGCGGGCTGGGGCTGGCCATTTCAC
GCGGACTGGCCCTGCTGATGGGCGGCACGCTGCAACTGGCCGAAGCCGGACAGACAGGCAGTCTTTTCCGTCTTGCCCTG
CCCCTGCCGGCGGCGCAAGAAGCTGCCGCCTCCGGCATCACACCGGCCCTGCCTGCGGCAGAGGCCCCCGTCACAACAAA
AAAACCTGCTGCCGCGGCGGCAGCAGGCGCGCATATTCTGCTGGTGGAAGACAACACACTTAATCAGGAATTCATATCGC
TGTTTCTGCAGGAGGGCGGTTACACCGTGACCGCGGCAGACAACGGCACCGGTGCGCTGGAAAATCTGGAAAAGCGGTCT
TTTGATGCGGTTCTGATGGATGTGCAGATGCCCGGCATGAACGGACTGGAAACCACAAAGCGCATCAGAAACAGCGGCAG
GGCGTGGGCGCGGATTCCCGTCATTGCCCTTACCGCCAACAACATGGCCGGAGACAGAGAATATTATCTGGCAAGCGGCA
TGAACGGCTATGTGGAAAAACCGGTGAACAAAGCGCAGCTTTTCGGCGAAATTGAAAGATGTCTGACAGAGGCACACGCA
GACACCGCCCCGTAA

Upstream 100 bases:

>100_bases
GAGTACGTCACCACGTGTCTTCATGGGATGACATTTCTATTGTCCCAGACAGGGGTGACAATATCATTGTCCGGTAACAA
AGGGCTTTGTACGGGTTGAC

Downstream 100 bases:

>100_bases
CCCCCTGACAGCCATGAAAAAGCCCGCCGGAAGGCGGGCTGACAGGTATTTCAAGCCGCTGCGGTCACGACCGGTGCCGC
AGCACGAAGTCTTCAAACTC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MYPDKNDVICFDVCDTGPGIPHSKRHLLFESFVQLDGSLSRQHQGSGLGLAISRGLALLMGGTLQLAEAGQTGSLFRLAL
PLPAAQEAAASGITPALPAAEAPVTTKKPAAAAAAGAHILLVEDNTLNQEFISLFLQEGGYTVTAADNGTGALENLEKRS
FDAVLMDVQMPGMNGLETTKRIRNSGRAWARIPVIALTANNMAGDREYYLASGMNGYVEKPVNKAQLFGEIERCLTEAHA
DTAP

Sequences:

>Translated_244_residues
MYPDKNDVICFDVCDTGPGIPHSKRHLLFESFVQLDGSLSRQHQGSGLGLAISRGLALLMGGTLQLAEAGQTGSLFRLAL
PLPAAQEAAASGITPALPAAEAPVTTKKPAAAAAAGAHILLVEDNTLNQEFISLFLQEGGYTVTAADNGTGALENLEKRS
FDAVLMDVQMPGMNGLETTKRIRNSGRAWARIPVIALTANNMAGDREYYLASGMNGYVEKPVNKAQLFGEIERCLTEAHA
DTAP
>Mature_244_residues
MYPDKNDVICFDVCDTGPGIPHSKRHLLFESFVQLDGSLSRQHQGSGLGLAISRGLALLMGGTLQLAEAGQTGSLFRLAL
PLPAAQEAAASGITPALPAAEAPVTTKKPAAAAAAGAHILLVEDNTLNQEFISLFLQEGGYTVTAADNGTGALENLEKRS
FDAVLMDVQMPGMNGLETTKRIRNSGRAWARIPVIALTANNMAGDREYYLASGMNGYVEKPVNKAQLFGEIERCLTEAHA
DTAP

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=219, Percent_Identity=31.5068493150685, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI48994928, Length=231, Percent_Identity=31.6017316017316, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87081816, Length=222, Percent_Identity=29.7297297297297, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI87082012, Length=122, Percent_Identity=33.6065573770492, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI145693157, Length=125, Percent_Identity=38.4, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1789149, Length=209, Percent_Identity=30.622009569378, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1790437, Length=122, Percent_Identity=32.7868852459016, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787229, Length=118, Percent_Identity=29.6610169491525, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=122, Percent_Identity=36.8852459016393, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322044, Length=83, Percent_Identity=48.1927710843374, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6323034, Length=139, Percent_Identity=30.2158273381295, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 25779; Mature: 25779

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYPDKNDVICFDVCDTGPGIPHSKRHLLFESFVQLDGSLSRQHQGSGLGLAISRGLALLM
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHCHHEEC
GGTLQLAEAGQTGSLFRLALPLPAAQEAAASGITPALPAAEAPVTTKKPAAAAAAGAHIL
CCCEEEECCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCEEEE
LVEDNTLNQEFISLFLQEGGYTVTAADNGTGALENLEKRSFDAVLMDVQMPGMNGLETTK
EEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
RIRNSGRAWARIPVIALTANNMAGDREYYLASGMNGYVEKPVNKAQLFGEIERCLTEAHA
HHHHCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHCC
DTAP
CCCC
>Mature Secondary Structure
MYPDKNDVICFDVCDTGPGIPHSKRHLLFESFVQLDGSLSRQHQGSGLGLAISRGLALLM
CCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCCCCCCHHHHHCHHEEC
GGTLQLAEAGQTGSLFRLALPLPAAQEAAASGITPALPAAEAPVTTKKPAAAAAAGAHIL
CCCEEEECCCCCCCEEEEEECCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHCCEEEE
LVEDNTLNQEFISLFLQEGGYTVTAADNGTGALENLEKRSFDAVLMDVQMPGMNGLETTK
EEECCCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCCCHHHHH
RIRNSGRAWARIPVIALTANNMAGDREYYLASGMNGYVEKPVNKAQLFGEIERCLTEAHA
HHHHCCCCEEEEEEEEEECCCCCCCCEEEEECCCCCHHHCCCHHHHHHHHHHHHHHHHCC
DTAP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA