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The map label for this gene is atoS [H]

Identifier: 78355552

GI number: 78355552

Start: 511888

End: 513384

Strand: Reverse

Name: atoS [H]

Synonym: Dde_0505

Alternate gene names: 78355552

Gene position: 513384-511888 (Counterclockwise)

Preceding gene: 78355556

Following gene: 78355551

Centisome position: 13.76

GC content: 59.32

Gene sequence:

>1497_bases
ATGACCGCAAACACACACCAGCCGCCGCTGGCGGAACTGCACCCCGTGCGGCCTGTCAGACTGGGCATAGCCACAGTGGG
CACGGGAAGCAGTCTGGAGCTTCTGGCGGGGCTGTTCAGCCGCACCGATTTCCGGCAGGCATTTCCGCAGGTATGCATCA
CCGCACTGCTGCTGGATGATGACACCCAGCCGCCCGCCGGTCTGGCGCACATTCCGCGCTATGCACAGCTTGCGCCGCTG
CTGGAAGCGCAACCGCTGACAACCGTGCTGGCAGACATGACGGAAGACGGCAGACACATGGCCTGTCTGCGCCGCGAGGC
ACCGCCGCGCATGGCAGTGCTGGACGCCTGTACCGTCACGGCTTTTTTCAGCATCATCACATCGGAACAGCTGTGCCGCA
CATGCCATGTGCATCTTTCACATGCGCGCACTCTTTTCGCCGCTCTCATCGACCAGATTGACGAAGACATTCTGCTGCTG
GACGCGGAAGGGCGCATAACCGACCTGAACAAAAAGGTGCTGGAACGGCGCGGCGGGGCCAAAGAAGACTGGCTGGGCCG
CTACTGCTGCGATCTGGAAGGACAGGACTTCTGCTCCACCTGTCAGGGAGCCTGCCCGTTTGAAGAGACCCTGCGCACAG
GAGCCAAGGCGGAACAGATACACACCCGCGTAACCCCCGAAGGCAAGGTAAGTTACCACCGCGTGTACACGTATCCCGTG
CATGACGAACACGGCACCCTTACACGGGTCATAGAAATGCGCCGCGACATCACAGGCCGCACCAACATGGAACGCAAACT
CCATCAATCTGAAAAAATGGCGGCCATAGGCGAACTGGCAACCTACATCGCGCATGAAATCCGCAACCCGCTTTTTGCCA
TCGGCGGCTTTGCCAATGCGCTTCTCCGGTCGCCTTCGCTGGACGACAACGCACGCGAAAAAGCACGCATCATATTGGAA
GAATCCAGACGGCTGGACACAATTCTGCGCAGCACCATGAATTTTGCCAAGCCCAGCGACCCGCGCCGCGGCGATGTGGA
CATGAACCACATAGTGCGCGACACCATGTGGCTGATGCGGCTGAACGATGAAAAACGCAGCATCACCACCGGCGTGGATC
TGACAGAACCGCTGCCTCTGGCGCGAGGCGATGCCGACATGACCAAACAGTGCCTTATCAACCTTGTTAAAAACGCACAG
GAAGCCATGCCCCGGGGCGGCAGCTTGACGGTGCGTACCGGAATGAAGCAAAGGGGAATCTTCATTCAGGTAGAGGATAC
CGGAACCGGCATTCCCGAAGAGATACGGGAAAATGTCTTCAGCCCGTTTTTTTCCACCAAAGACAAAGGGGCCGGTCTGG
GCCTTGCCATGACCAAAAAACTTATCGAGGAAATGGGCGGCGCCGTTGAACTGCAGACCGCCGAGGGCAAGGGGACATCC
GTCACCCTGTTTCTGCAGCCGCTGCTGACGGTGGACGACGCACCGGCAGCACTCTGA

Upstream 100 bases:

>100_bases
GGTAACTGTGCAACCCGCGCATTGCCACGGCGGGACTCACTATGCAAGTAAAATAATGCCGGCCGGACGGGACCGCGTAC
GTCACAGTCAAGGAGGCATC

Downstream 100 bases:

>100_bases
CCCGTTTACCCGTCTTTCAGGAGCCTGAACCGCATGAAACAGCAGGTTATCGTACTTGCCACCCGCAACAGAGGAAAAAT
CGCGGAACTTTCCGCCATGC

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MTANTHQPPLAELHPVRPVRLGIATVGTGSSLELLAGLFSRTDFRQAFPQVCITALLLDDDTQPPAGLAHIPRYAQLAPL
LEAQPLTTVLADMTEDGRHMACLRREAPPRMAVLDACTVTAFFSIITSEQLCRTCHVHLSHARTLFAALIDQIDEDILLL
DAEGRITDLNKKVLERRGGAKEDWLGRYCCDLEGQDFCSTCQGACPFEETLRTGAKAEQIHTRVTPEGKVSYHRVYTYPV
HDEHGTLTRVIEMRRDITGRTNMERKLHQSEKMAAIGELATYIAHEIRNPLFAIGGFANALLRSPSLDDNAREKARIILE
ESRRLDTILRSTMNFAKPSDPRRGDVDMNHIVRDTMWLMRLNDEKRSITTGVDLTEPLPLARGDADMTKQCLINLVKNAQ
EAMPRGGSLTVRTGMKQRGIFIQVEDTGTGIPEEIRENVFSPFFSTKDKGAGLGLAMTKKLIEEMGGAVELQTAEGKGTS
VTLFLQPLLTVDDAPAAL

Sequences:

>Translated_498_residues
MTANTHQPPLAELHPVRPVRLGIATVGTGSSLELLAGLFSRTDFRQAFPQVCITALLLDDDTQPPAGLAHIPRYAQLAPL
LEAQPLTTVLADMTEDGRHMACLRREAPPRMAVLDACTVTAFFSIITSEQLCRTCHVHLSHARTLFAALIDQIDEDILLL
DAEGRITDLNKKVLERRGGAKEDWLGRYCCDLEGQDFCSTCQGACPFEETLRTGAKAEQIHTRVTPEGKVSYHRVYTYPV
HDEHGTLTRVIEMRRDITGRTNMERKLHQSEKMAAIGELATYIAHEIRNPLFAIGGFANALLRSPSLDDNAREKARIILE
ESRRLDTILRSTMNFAKPSDPRRGDVDMNHIVRDTMWLMRLNDEKRSITTGVDLTEPLPLARGDADMTKQCLINLVKNAQ
EAMPRGGSLTVRTGMKQRGIFIQVEDTGTGIPEEIRENVFSPFFSTKDKGAGLGLAMTKKLIEEMGGAVELQTAEGKGTS
VTLFLQPLLTVDDAPAAL
>Mature_497_residues
TANTHQPPLAELHPVRPVRLGIATVGTGSSLELLAGLFSRTDFRQAFPQVCITALLLDDDTQPPAGLAHIPRYAQLAPLL
EAQPLTTVLADMTEDGRHMACLRREAPPRMAVLDACTVTAFFSIITSEQLCRTCHVHLSHARTLFAALIDQIDEDILLLD
AEGRITDLNKKVLERRGGAKEDWLGRYCCDLEGQDFCSTCQGACPFEETLRTGAKAEQIHTRVTPEGKVSYHRVYTYPVH
DEHGTLTRVIEMRRDITGRTNMERKLHQSEKMAAIGELATYIAHEIRNPLFAIGGFANALLRSPSLDDNAREKARIILEE
SRRLDTILRSTMNFAKPSDPRRGDVDMNHIVRDTMWLMRLNDEKRSITTGVDLTEPLPLARGDADMTKQCLINLVKNAQE
AMPRGGSLTVRTGMKQRGIFIQVEDTGTGIPEEIRENVFSPFFSTKDKGAGLGLAMTKKLIEEMGGAVELQTAEGKGTSV
TLFLQPLLTVDDAPAAL

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=26.7806267806268, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=31.6666666666667, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=30.9322033898305, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=271, Percent_Identity=25.830258302583, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI87081816, Length=202, Percent_Identity=29.7029702970297, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI145693157, Length=267, Percent_Identity=26.2172284644195, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1786600, Length=261, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1789149, Length=244, Percent_Identity=24.1803278688525, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=246, Percent_Identity=27.6422764227642, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 55090; Mature: 54959

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTANTHQPPLAELHPVRPVRLGIATVGTGSSLELLAGLFSRTDFRQAFPQVCITALLLDD
CCCCCCCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DTQPPAGLAHIPRYAQLAPLLEAQPLTTVLADMTEDGRHMACLRREAPPRMAVLDACTVT
CCCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH
AFFSIITSEQLCRTCHVHLSHARTLFAALIDQIDEDILLLDAEGRITDLNKKVLERRGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCCC
KEDWLGRYCCDLEGQDFCSTCQGACPFEETLRTGAKAEQIHTRVTPEGKVSYHRVYTYPV
CHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCEEEEEEEEEEC
HDEHGTLTRVIEMRRDITGRTNMERKLHQSEKMAAIGELATYIAHEIRNPLFAIGGFANA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHH
LLRSPSLDDNAREKARIILEESRRLDTILRSTMNFAKPSDPRRGDVDMNHIVRDTMWLMR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LNDEKRSITTGVDLTEPLPLARGDADMTKQCLINLVKNAQEAMPRGGSLTVRTGMKQRGI
CCCCHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCE
FIQVEDTGTGIPEEIRENVFSPFFSTKDKGAGLGLAMTKKLIEEMGGAVELQTAEGKGTS
EEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCE
VTLFLQPLLTVDDAPAAL
EEEEEEEHHCCCCCCCCC
>Mature Secondary Structure 
TANTHQPPLAELHPVRPVRLGIATVGTGSSLELLAGLFSRTDFRQAFPQVCITALLLDD
CCCCCCCCHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
DTQPPAGLAHIPRYAQLAPLLEAQPLTTVLADMTEDGRHMACLRREAPPRMAVLDACTVT
CCCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHH
AFFSIITSEQLCRTCHVHLSHARTLFAALIDQIDEDILLLDAEGRITDLNKKVLERRGGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEHHHHHHHHHCCCC
KEDWLGRYCCDLEGQDFCSTCQGACPFEETLRTGAKAEQIHTRVTPEGKVSYHRVYTYPV
CHHHHHHHHCCCCCCHHHHHCCCCCCHHHHHHCCCHHHHHHHCCCCCCCEEEEEEEEEEC
HDEHGTLTRVIEMRRDITGRTNMERKLHQSEKMAAIGELATYIAHEIRNPLFAIGGFANA
CCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEHHHHHHH
LLRSPSLDDNAREKARIILEESRRLDTILRSTMNFAKPSDPRRGDVDMNHIVRDTMWLMR
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LNDEKRSITTGVDLTEPLPLARGDADMTKQCLINLVKNAQEAMPRGGSLTVRTGMKQRGI
CCCCHHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCE
FIQVEDTGTGIPEEIRENVFSPFFSTKDKGAGLGLAMTKKLIEEMGGAVELQTAEGKGTS
EEEEECCCCCCCHHHHHHHHCHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCE
VTLFLQPLLTVDDAPAAL
EEEEEEEHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]