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The map label for this gene is bepF [H]

Identifier: 78355449

GI number: 78355449

Start: 397987

End: 399198

Strand: Reverse

Name: bepF [H]

Synonym: Dde_0402

Alternate gene names: 78355449

Gene position: 399198-397987 (Counterclockwise)

Preceding gene: 78355450

Following gene: 78355448

Centisome position: 10.7

GC content: 61.55

Gene sequence:

>1212_bases
ATGGATTTACGTATGCATAACCATTGTCATCTGCGATCCGGTCATCCTGCACCGGCAACATCGCGCACAGTTCACGTCTC
CGCGGTATTCACGGCATCGGTACTGCTGTGGTTCACCGTGCTGGCCACCTTTGCCTATGCGGCGCCCGGCGCCGGAGCAC
AAGGCCCTGCCCCCGCCGTCACCGTGGAAAAAGTTCAGGTGAAGGACGCCAACCCCCCGCAGGCATATGTGGGCAGGGTT
GAAGCCATTCAGGCAGTGGACCTGCAGCCGAGAGTCGAAGGATATCTCACGGCAGTAAACGTCACCGAAGGCGGCATGGT
AAACGCCGGTGACGTTCTTTTTGTCATCGAGCAGACAACCTACCGTGCCCGTGTCAATGCCGACGCCGCCGCCGTGGACA
AGGCACAGGCTTCGCTGGACAGGGCCGAAAAATACTTAAAGCGCCTGCGTTCCACCCGTAAAAGCGGTGTGGCCGCGGCA
GACATGGACGCGGCAGTCAGCGACCAGCTGCAGGCAAAGGCCCAGCTGCAGGAAGCCATGGCCGCGCTTGAGCAGTCCAG
ACTTAATCTGGGGTACACCACCATCACTGCTCCCATCCACGGACGCATCGGTCGTGTTCAGGTGACCAAGGGCAACCTTG
TGACTCCCTCCACGGGAGCGCTGGCACGCATCGTACAGGTAGACCCCATCCGTGTGGTCTTTTCGCTGAACGAGCAGGAT
TATCTGGCCATGAGCCGGCAGGTGTCTCCGCTGCCTTCGGGCGAGGTTTCATTTTCCGACGTGGTCGTGCCGCGCCTACG
CCTTTCCGACGGAACGGTCTACCCCGCACAGGGACGCATAGATTTTGTGGATAACGAAATAGATGCCCGTACCGGCACCA
TTGCCGTGCGCGCGGTGTTTGACAACCCGGGCCAGCTGCTGCTGCCGGGCGGTTATGTAACCGTGGAACTGACCAAGGCC
GCCGCAAAGCCGCGCCCGGTGGTACCGCAGGCAGCCGTGCAGGAAGACAAGGACGGCCGGTTTGTACTGGTAGTGGGAGA
AGGCAACGTGGTGAGTGTACGCCGCATCGTCACCGGAGCAACCGTCGGCGCCAGCTGGGTTGTGGAAGACGGACTGCAGG
GCGGCGAAACCATCATTGTGCACGGACTGCAGAAAGCCCGCGTGGGCCAGCCCGTGGAACCCAAGCTTGACGCCACCCGC
GGTCAGGAGTAG

Upstream 100 bases:

>100_bases
GAACGCATGCGCTGCTGGTCAGAAGTGGTGGATATCATCATCAGAGAACTGGAAACGACCCGATAGACGGGCACTCGTCG
GGATTCCACAAACTTTTTTT

Downstream 100 bases:

>100_bases
CCCATGATCGCCGAACTGTTTGTAAGCCGCCCGCGGCTGGCGATGGTCATATCACTGGTCATCACCATTGCCGGTCTGGT
GACCATGTTCACCATTCCCG

Product: secretion protein HlyD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MDLRMHNHCHLRSGHPAPATSRTVHVSAVFTASVLLWFTVLATFAYAAPGAGAQGPAPAVTVEKVQVKDANPPQAYVGRV
EAIQAVDLQPRVEGYLTAVNVTEGGMVNAGDVLFVIEQTTYRARVNADAAAVDKAQASLDRAEKYLKRLRSTRKSGVAAA
DMDAAVSDQLQAKAQLQEAMAALEQSRLNLGYTTITAPIHGRIGRVQVTKGNLVTPSTGALARIVQVDPIRVVFSLNEQD
YLAMSRQVSPLPSGEVSFSDVVVPRLRLSDGTVYPAQGRIDFVDNEIDARTGTIAVRAVFDNPGQLLLPGGYVTVELTKA
AAKPRPVVPQAAVQEDKDGRFVLVVGEGNVVSVRRIVTGATVGASWVVEDGLQGGETIIVHGLQKARVGQPVEPKLDATR
GQE

Sequences:

>Translated_403_residues
MDLRMHNHCHLRSGHPAPATSRTVHVSAVFTASVLLWFTVLATFAYAAPGAGAQGPAPAVTVEKVQVKDANPPQAYVGRV
EAIQAVDLQPRVEGYLTAVNVTEGGMVNAGDVLFVIEQTTYRARVNADAAAVDKAQASLDRAEKYLKRLRSTRKSGVAAA
DMDAAVSDQLQAKAQLQEAMAALEQSRLNLGYTTITAPIHGRIGRVQVTKGNLVTPSTGALARIVQVDPIRVVFSLNEQD
YLAMSRQVSPLPSGEVSFSDVVVPRLRLSDGTVYPAQGRIDFVDNEIDARTGTIAVRAVFDNPGQLLLPGGYVTVELTKA
AAKPRPVVPQAAVQEDKDGRFVLVVGEGNVVSVRRIVTGATVGASWVVEDGLQGGETIIVHGLQKARVGQPVEPKLDATR
GQE
>Mature_403_residues
MDLRMHNHCHLRSGHPAPATSRTVHVSAVFTASVLLWFTVLATFAYAAPGAGAQGPAPAVTVEKVQVKDANPPQAYVGRV
EAIQAVDLQPRVEGYLTAVNVTEGGMVNAGDVLFVIEQTTYRARVNADAAAVDKAQASLDRAEKYLKRLRSTRKSGVAAA
DMDAAVSDQLQAKAQLQEAMAALEQSRLNLGYTTITAPIHGRIGRVQVTKGNLVTPSTGALARIVQVDPIRVVFSLNEQD
YLAMSRQVSPLPSGEVSFSDVVVPRLRLSDGTVYPAQGRIDFVDNEIDARTGTIAVRAVFDNPGQLLLPGGYVTVELTKA
AAKPRPVVPQAAVQEDKDGRFVLVVGEGNVVSVRRIVTGATVGASWVVEDGLQGGETIIVHGLQKARVGQPVEPKLDATR
GQE

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1789665, Length=346, Percent_Identity=34.6820809248555, Blast_Score=168, Evalue=5e-43,
Organism=Escherichia coli, GI1789929, Length=359, Percent_Identity=32.033426183844, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786668, Length=347, Percent_Identity=33.7175792507205, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=29.1925465838509, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI87081951, Length=141, Percent_Identity=30.4964539007092, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42860; Mature: 42860

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLRMHNHCHLRSGHPAPATSRTVHVSAVFTASVLLWFTVLATFAYAAPGAGAQGPAPAV
CCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
TVEKVQVKDANPPQAYVGRVEAIQAVDLQPRVEGYLTAVNVTEGGMVNAGDVLFVIEQTT
EEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCEECCCCEEEEEECCE
YRARVNADAAAVDKAQASLDRAEKYLKRLRSTRKSGVAAADMDAAVSDQLQAKAQLQEAM
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHH
AALEQSRLNLGYTTITAPIHGRIGRVQVTKGNLVTPSTGALARIVQVDPIRVVFSLNEQD
HHHHHHCCCCCEEEEEEECCCCCEEEEEECCCEECCCCCCEEEEEEECCEEEEEEECCCH
YLAMSRQVSPLPSGEVSFSDVVVPRLRLSDGTVYPAQGRIDFVDNEIDARTGTIAVRAVF
HHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEECCCCEEEEECCCCCCCCCEEEEEEEE
DNPGQLLLPGGYVTVELTKAAAKPRPVVPQAAVQEDKDGRFVLVVGEGNVVSVRRIVTGA
CCCCCEEECCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEECCCCEEEEEEEEECC
TVGASWVVEDGLQGGETIIVHGLQKARVGQPVEPKLDATRGQE
CCCCCEEECCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLRMHNHCHLRSGHPAPATSRTVHVSAVFTASVLLWFTVLATFAYAAPGAGAQGPAPAV
CCCCCCCCEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
TVEKVQVKDANPPQAYVGRVEAIQAVDLQPRVEGYLTAVNVTEGGMVNAGDVLFVIEQTT
EEEEEEECCCCCCHHHHHHHHEEEEECCCCCCCEEEEEEEECCCCEECCCCEEEEEECCE
YRARVNADAAAVDKAQASLDRAEKYLKRLRSTRKSGVAAADMDAAVSDQLQAKAQLQEAM
EEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHHHHHHHHHHH
AALEQSRLNLGYTTITAPIHGRIGRVQVTKGNLVTPSTGALARIVQVDPIRVVFSLNEQD
HHHHHHCCCCCEEEEEEECCCCCEEEEEECCCEECCCCCCEEEEEEECCEEEEEEECCCH
YLAMSRQVSPLPSGEVSFSDVVVPRLRLSDGTVYPAQGRIDFVDNEIDARTGTIAVRAVF
HHHHHCCCCCCCCCCCCCCCEEEEEEEECCCEEECCCCEEEEECCCCCCCCCEEEEEEEE
DNPGQLLLPGGYVTVELTKAAAKPRPVVPQAAVQEDKDGRFVLVVGEGNVVSVRRIVTGA
CCCCCEEECCCEEEEEEEECCCCCCCCCCCHHHCCCCCCCEEEEECCCCEEEEEEEEECC
TVGASWVVEDGLQGGETIIVHGLQKARVGQPVEPKLDATRGQE
CCCCCEEECCCCCCCCEEEEECCHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]