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The map label for this gene is hbpA [H]

Identifier: 78355418

GI number: 78355418

Start: 364717

End: 366348

Strand: Reverse

Name: hbpA [H]

Synonym: Dde_0371

Alternate gene names: 78355418

Gene position: 366348-364717 (Counterclockwise)

Preceding gene: 78355420

Following gene: 78355417

Centisome position: 9.82

GC content: 61.52

Gene sequence:

>1632_bases
TTGTTCCGGTCTCAGGCGTCAGCAAGTGCCCGAAGCGTTCTGCCCGCTCCCCGTTCATACGGGGGGACTCTTGCGGCCGT
GGCTTTTGCCTGCGTGCTCGTGTTTTCCGCTCACGGCGCAGCGGCTGCGGCAACCACAGCCGGGCAGACAGTCACCGTGG
CCATGTTCCAGCGCATTGCCAGTCTGGACCCGGCACACAGCAGCCTGTACGAACCCCACAGCATCGCTGCCAATGTTTTT
GAAACACTGGTCACCGTTTCGCGCAACGGCACCGTGCAGCCCGCTGTGGCGGAATCGTGGAATGTGACGCCCGACGGCAG
GCGCTGGACCTTTACCCTGCATGAAGGCCGCAGCTTTCACGACGGTTCTCCCCTGAACGCCTATGCCGTGGAATACAGCT
TTCAGCGGCTCATGGATCCGGCGCACCCGCAGTACACCCCCTATCCCGACTGGAAACGGCTGCTGTTCGGTCAGGTCAAT
TCCATACGTGCTCTGGATGACAACACGCTGGAAATAGAACTGGACAACCCCTATGCCCCGCTGCTGCATAATCTGGCAAC
GCCCGGTGCCAGCATAGTCTCGCCGCGCTCGCTGCAGGAGATGCACGACGGCAGAACCGCCATCCCTGCCGGTTCAGGGC
CGTTCCGCGTGGCGTCATATTCGCCCGAGGCAGTCACCCTGATACCCGCCGCAGGGCATACCCCGCCGCCGCGCTGCAAT
GTCCGCTACGAATACTATGCCTCCAGCAGCAGCGCTCTGGAAGCGCTGCTCTCCGGCAGGGCCGACATTGTACCCGGCCT
GACAGAACAGGATGAAAAAACGGCTCAGCGGCTGGGTGCCTACACCATCATCAGACACCCGCAGCTTTCGGTCATTTTTC
TGGCCTGCAACGGTGCCAGTGAAAAAATGCGCTCCCCCGAAATCCGCCGCGCCGTATCATTGAGCATCAACAGAAACAGT
CTGGCCACCGTGGTGCTGGGCGCCAACGGCATGCCAGCCACAGGGCTGCTGCCGCCGGAAATGTGGGCCAAAGACCATTC
GCTGCCTCCGTACGAATACGCGCCGGATAAAGCCCGGCAACTTCTGCTTCGCAGCGGCTACCCGCAGGGCATCAGCCTTA
CGGCGCTGCAGCTCGACGCCTCACGGCCTTTCATGCCTTCGCCGCGGCTTTTCGCCGTCACGCTCAAATATCTCATGGCC
GGAGCCGGCATAACGCTTTCCATAGAAACCCTGCCCCCCGATGCTCTGCGGGAACGCCGTGCACAGGGCGACTATGATCT
GTTCATCAACGCATGGGTTGCCGATACGGCAGACCCCGACAATCTGTACAGCACGCACCTGTATGCAGGACCTGACAACC
CGCTGCACAGGGTACACATACCCGAGCTGGACCGGCTGATAGAAGAAAGTGTTTCCACCCCCGTACGCGGCGAAAGGGCG
CGGGCCTACCGCCGCATACAGCGTATAGAACGTGAACAGATGCCGTGCATACCCGTCATGCACAGCAGCCTGCCGGTCAT
ACTGCGCCGCGGAATTTCCGGCATGCGCATTACCACGGGCTCGTACCTGATCTTTCGCAACACCGTAAAAACAGCGCCTG
CAGACCGCGCTCAGCAACGGCCGGCACCATGA

Upstream 100 bases:

>100_bases
CATTCCCTTGTGATTGACAACAGGGTAGCATGTATCCTTGCAAGGCTTATCCGCTTTCTATATAGTCCTTCAAATGTGAA
AAAGAGCACAAGGAGCTGCT

Downstream 100 bases:

>100_bases
AGATCAACCTCAGCATTTCATCCATCAGACTACGGGTCATTCTTGTAACCCTGCTTGTGGCGCTTGTGCCTGTCTGCACC
ATGACCGTGGCGGGGCTGCT

Product: dipeptide ABC transporter substrate-binding protein

Products: NA

Alternate protein names: Hemin-binding lipoprotein [H]

Number of amino acids: Translated: 543; Mature: 543

Protein sequence:

>543_residues
MFRSQASASARSVLPAPRSYGGTLAAVAFACVLVFSAHGAAAAATTAGQTVTVAMFQRIASLDPAHSSLYEPHSIAANVF
ETLVTVSRNGTVQPAVAESWNVTPDGRRWTFTLHEGRSFHDGSPLNAYAVEYSFQRLMDPAHPQYTPYPDWKRLLFGQVN
SIRALDDNTLEIELDNPYAPLLHNLATPGASIVSPRSLQEMHDGRTAIPAGSGPFRVASYSPEAVTLIPAAGHTPPPRCN
VRYEYYASSSSALEALLSGRADIVPGLTEQDEKTAQRLGAYTIIRHPQLSVIFLACNGASEKMRSPEIRRAVSLSINRNS
LATVVLGANGMPATGLLPPEMWAKDHSLPPYEYAPDKARQLLLRSGYPQGISLTALQLDASRPFMPSPRLFAVTLKYLMA
GAGITLSIETLPPDALRERRAQGDYDLFINAWVADTADPDNLYSTHLYAGPDNPLHRVHIPELDRLIEESVSTPVRGERA
RAYRRIQRIEREQMPCIPVMHSSLPVILRRGISGMRITTGSYLIFRNTVKTAPADRAQQRPAP

Sequences:

>Translated_543_residues
MFRSQASASARSVLPAPRSYGGTLAAVAFACVLVFSAHGAAAAATTAGQTVTVAMFQRIASLDPAHSSLYEPHSIAANVF
ETLVTVSRNGTVQPAVAESWNVTPDGRRWTFTLHEGRSFHDGSPLNAYAVEYSFQRLMDPAHPQYTPYPDWKRLLFGQVN
SIRALDDNTLEIELDNPYAPLLHNLATPGASIVSPRSLQEMHDGRTAIPAGSGPFRVASYSPEAVTLIPAAGHTPPPRCN
VRYEYYASSSSALEALLSGRADIVPGLTEQDEKTAQRLGAYTIIRHPQLSVIFLACNGASEKMRSPEIRRAVSLSINRNS
LATVVLGANGMPATGLLPPEMWAKDHSLPPYEYAPDKARQLLLRSGYPQGISLTALQLDASRPFMPSPRLFAVTLKYLMA
GAGITLSIETLPPDALRERRAQGDYDLFINAWVADTADPDNLYSTHLYAGPDNPLHRVHIPELDRLIEESVSTPVRGERA
RAYRRIQRIEREQMPCIPVMHSSLPVILRRGISGMRITTGSYLIFRNTVKTAPADRAQQRPAP
>Mature_543_residues
MFRSQASASARSVLPAPRSYGGTLAAVAFACVLVFSAHGAAAAATTAGQTVTVAMFQRIASLDPAHSSLYEPHSIAANVF
ETLVTVSRNGTVQPAVAESWNVTPDGRRWTFTLHEGRSFHDGSPLNAYAVEYSFQRLMDPAHPQYTPYPDWKRLLFGQVN
SIRALDDNTLEIELDNPYAPLLHNLATPGASIVSPRSLQEMHDGRTAIPAGSGPFRVASYSPEAVTLIPAAGHTPPPRCN
VRYEYYASSSSALEALLSGRADIVPGLTEQDEKTAQRLGAYTIIRHPQLSVIFLACNGASEKMRSPEIRRAVSLSINRNS
LATVVLGANGMPATGLLPPEMWAKDHSLPPYEYAPDKARQLLLRSGYPQGISLTALQLDASRPFMPSPRLFAVTLKYLMA
GAGITLSIETLPPDALRERRAQGDYDLFINAWVADTADPDNLYSTHLYAGPDNPLHRVHIPELDRLIEESVSTPVRGERA
RAYRRIQRIEREQMPCIPVMHSSLPVILRRGISGMRITTGSYLIFRNTVKTAPADRAQQRPAP

Specific function: Important role in heme acquisition or metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=473, Percent_Identity=26.8498942917548, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789966, Length=446, Percent_Identity=25.1121076233184, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1787052, Length=512, Percent_Identity=24.21875, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787551, Length=471, Percent_Identity=25.6900212314225, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI87081878, Length=528, Percent_Identity=23.1060606060606, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787495, Length=505, Percent_Identity=22.970297029703, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789887, Length=509, Percent_Identity=23.3791748526523, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1789397, Length=487, Percent_Identity=24.2299794661191, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082063, Length=273, Percent_Identity=26.007326007326, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 59350; Mature: 59350

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRSQASASARSVLPAPRSYGGTLAAVAFACVLVFSAHGAAAAATTAGQTVTVAMFQRIA
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
SLDPAHSSLYEPHSIAANVFETLVTVSRNGTVQPAVAESWNVTPDGRRWTFTLHEGRSFH
HCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCC
DGSPLNAYAVEYSFQRLMDPAHPQYTPYPDWKRLLFGQVNSIRALDDNTLEIELDNPYAP
CCCCCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCHHH
LLHNLATPGASIVSPRSLQEMHDGRTAIPAGSGPFRVASYSPEAVTLIPAAGHTPPPRCN
HHHHHCCCCCCCCCCHHHHHHHCCCEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCC
VRYEYYASSSSALEALLSGRADIVPGLTEQDEKTAQRLGAYTIIRHPQLSVIFLACNGAS
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCEEEEEEEECCCH
EKMRSPEIRRAVSLSINRNSLATVVLGANGMPATGLLPPEMWAKDHSLPPYEYAPDKARQ
HHHCCCHHHHEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHH
LLLRSGYPQGISLTALQLDASRPFMPSPRLFAVTLKYLMAGAGITLSIETLPPDALRERR
HHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
AQGDYDLFINAWVADTADPDNLYSTHLYAGPDNPLHRVHIPELDRLIEESVSTPVRGERA
CCCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCCHHH
RAYRRIQRIEREQMPCIPVMHSSLPVILRRGISGMRITTGSYLIFRNTVKTAPADRAQQR
HHHHHHHHHHHHCCCCCEEHHCCHHHHHHCCCCCEEEECCCEEEEECCCCCCCCHHHHCC
PAP
CCC
>Mature Secondary Structure
MFRSQASASARSVLPAPRSYGGTLAAVAFACVLVFSAHGAAAAATTAGQTVTVAMFQRIA
CCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHH
SLDPAHSSLYEPHSIAANVFETLVTVSRNGTVQPAVAESWNVTPDGRRWTFTLHEGRSFH
HCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCEEEEEEECCCCCC
DGSPLNAYAVEYSFQRLMDPAHPQYTPYPDWKRLLFGQVNSIRALDDNTLEIELDNPYAP
CCCCCCEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCEEEECCCEEEEEECCCHHH
LLHNLATPGASIVSPRSLQEMHDGRTAIPAGSGPFRVASYSPEAVTLIPAAGHTPPPRCN
HHHHHCCCCCCCCCCHHHHHHHCCCEECCCCCCCEEEEECCCCEEEEEECCCCCCCCCCC
VRYEYYASSSSALEALLSGRADIVPGLTEQDEKTAQRLGAYTIIRHPQLSVIFLACNGAS
EEEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCEEEEEEEECCCH
EKMRSPEIRRAVSLSINRNSLATVVLGANGMPATGLLPPEMWAKDHSLPPYEYAPDKARQ
HHHCCCHHHHEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHH
LLLRSGYPQGISLTALQLDASRPFMPSPRLFAVTLKYLMAGAGITLSIETLPPDALRERR
HHHHCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHH
AQGDYDLFINAWVADTADPDNLYSTHLYAGPDNPLHRVHIPELDRLIEESVSTPVRGERA
CCCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCCEEEECHHHHHHHHHHHCCCCCCHHH
RAYRRIQRIEREQMPCIPVMHSSLPVILRRGISGMRITTGSYLIFRNTVKTAPADRAQQR
HHHHHHHHHHHHCCCCCEEHHCCHHHHHHCCCCCEEEECCCEEEEECCCCCCCCHHHHCC
PAP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339409; 7542800; 2041470 [H]