| Definition | Desulfovibrio desulfuricans subsp. desulfuricans str. G20 chromosome, complete genome. |
|---|---|
| Accession | NC_007519 |
| Length | 3,730,232 |
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The map label for this gene is pbpC [H]
Identifier: 78355316
GI number: 78355316
Start: 254264
End: 256468
Strand: Reverse
Name: pbpC [H]
Synonym: Dde_0269
Alternate gene names: 78355316
Gene position: 256468-254264 (Counterclockwise)
Preceding gene: 78355317
Following gene: 78355314
Centisome position: 6.88
GC content: 65.58
Gene sequence:
>2205_bases ATGCCGCCGGCGCGCATTATGTGCAACGGTAACCCGCCGGAAACAGACTTTCCCATGCCTCTGACACAGCACCAGCCTCC CGCCACGCAGCACACGGCACGCACCCGCCCGGCGCTCATCCGCCCGGCGTTCATCCGCGCCGCGGCTGCCGTCGGCATAT CGCTGTTTTGTACGGTAATGCTGCTACTTGTTCTGGATGCGGCCTTTCCGCCCGACCTCTCGCGCTACAACCGGCGTTCC GTGCTGGTGACCGATGCAGAGGGCAGACTGCTGCACGCTTTTCTCAGTCCCGACGGCATGTGGCGGCTGCACACAACACC GCATGATGTGGACAGCCGGTACCTCGACATGCTCAGAACCTATGAAGACAAACGCTTCGGCATGCATCCGGGGGTGGACC CGCTGGCTGTTCTGCGGGCCGCGGCACAGCTTGCCGTTTCCGGGCATGTGGTATCCGGTGCGTCCACACTGTCCATGCAG GCAGCACGGCTGCTGCAGCCGCGGCCGCGTACACTGAAAGCCAAACTGACGGAAGCCCTGCGCGCCATGCAGCTGCACTG GCGCTACGGCAGCAACGGGGTGCTTTCCATCTATCTCACTCTGGCGCCGTTCGGGTCCAACATTGAAGGGGTGCGGGCCG CCTCGCTGGCATATTTCGGTAAAGAACCGCGCAGGCTGACCACGGGAGAAGCAGCGCTGCTTGTGGCACTGCCTCAGTCC CCCACGCAGCTGCGGCCGGACAGAAACCCTCTGGAAGCCCGCAAAGCGAGAGATAAGATTCTCGGCCGCATGCACGCCGC AGGCATTATCAGCGGCAGACAGCACACCGAAGCCCGCACGGAATCCATTCCGGCTGTCCGCAGGCAAATGCCCGCGCTGG CGTCTGTTCTGGCCCTGAACATGCGCAATGCAGCCCCCCGCCGTGAGCACATTGCCACCGCCCTGAGCCTGCCTGTACAG CACGCAGCCGAAACACTGTGCCAGCGTCATGCCCTGAGCATGGAGCAGGGAGCCGCCACCGCAGCCGTGGTGCTGCACCG CGCCACCCGGCAGGTGCGAGCCTATGTGGGCGGCAAAAATGCCGACGCTTCGCGCAATTATCTGGACCTGCCCCGCGCAC TGCGTTCACCCGGTTCCACGCTGAAGCCATTCATCTACGGACTGGCTTTCAGTGAACACATTCTGCATCCCGAAACCCTC ATCAGTGACGAAGCACACCGGTTCGGCGACTTCAGCCCGCGTAATTTCCGCAGGGGGTATCAGGGCGCTGTAACGGTGCG CGAGGCTCTGCGTGACTCACTGAACGTGCCCGCCGTCAGCGTGCTGTACGCACTGGGCCCCGACAGACTGGTTGCGGCGC TGCGTAACGCCGGTGCAACGCTGGCCGTGGAAGGCGATGCCACACTGCCCATAGCGCTGGGCGGTGCCGGCACCACTCTG CTGGACCTCACAACCCTGTATGCAGCACTGGCAGACGGCGGCACAGCGCTGCCGCCGCAGTTTGTTCCCGCCGTCCTGCC CGCCCCGCAGCAGGGATTCCGGCTGATGGACAGTGCTGCGGCATGGCAGGTCATTGATATTCTGAAAGACTCGCCGAGGC CGCAGGGCTATCTGTCAGCCGCGGCCGGCGGCAGACCTGTCGCCTTCAAAACGGGCACGTCATACGGATACCGCGACGCG TGGGCCGTGGGTGCTTCTCCTGACTGGGTGGTGGGGGTGTGGACAGGCAGGCCCGACGGCAGACCCCGCCCCGGCGCAGT GGGGCGCACCGCCGCTGTACCGCTGCTGCTTGATATTTTCGGCAGGTTGCCGCCGGATACTGGCCCGTGGCCTTCTCCCC CGGCAGGGGTGCTGGATGTGCGCGACAACCGCAGGCTGCCTACGGGGCTGCAGCGCTTTGTGCCGGGCAGCGGCACGGGC CTGCCTGTACTGGCCGGCGAGCCTCCGCGCATACTGCACCCGCAGCAGGGAGCCACTGTGGAATCACTGGGGCAGCAGGC AGGAGAAGGCATAGCTCTGCGCGCATCGGGCGGCACCGCCCCGCTGCGCTGGGTTGTCAACGGACTGCCCCTGCCCGAAG ACCAGCATTACTGGCTGCCGGACAGTGAAGGCTTTGCCCGGCTGACGCTGGTCGATGCGGCAGGACGCAGCGCCACAGTG CAGATCCGCATCATTCTGCCGCAGCAGCCGGCACTCGCCCCGTAA
Upstream 100 bases:
>100_bases CGACCCGCAGTTCGCCGTACGCGGCGAAGCCGGCAGCATGACCATCGCGCCGTAACAGCCCGGCCGGCAGAAACAACCGG AACTCCCGCGCCGGCGGCAT
Downstream 100 bases:
>100_bases TTCTTGTTCATACGGCCCCGCCTGCCGGCGGACGCCGGAAAAAAAAAGCGCACAGCCTGCGGGCCGTGCGCCTGTAGTCA TGGTTCCGGCTGTATTCAGC
Product: penicillin-binding protein 1C
Products: NA
Alternate protein names: PBP-1c; PBP1c; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Transpeptidase-like module [H]
Number of amino acids: Translated: 734; Mature: 733
Protein sequence:
>734_residues MPPARIMCNGNPPETDFPMPLTQHQPPATQHTARTRPALIRPAFIRAAAAVGISLFCTVMLLLVLDAAFPPDLSRYNRRS VLVTDAEGRLLHAFLSPDGMWRLHTTPHDVDSRYLDMLRTYEDKRFGMHPGVDPLAVLRAAAQLAVSGHVVSGASTLSMQ AARLLQPRPRTLKAKLTEALRAMQLHWRYGSNGVLSIYLTLAPFGSNIEGVRAASLAYFGKEPRRLTTGEAALLVALPQS PTQLRPDRNPLEARKARDKILGRMHAAGIISGRQHTEARTESIPAVRRQMPALASVLALNMRNAAPRREHIATALSLPVQ HAAETLCQRHALSMEQGAATAAVVLHRATRQVRAYVGGKNADASRNYLDLPRALRSPGSTLKPFIYGLAFSEHILHPETL ISDEAHRFGDFSPRNFRRGYQGAVTVREALRDSLNVPAVSVLYALGPDRLVAALRNAGATLAVEGDATLPIALGGAGTTL LDLTTLYAALADGGTALPPQFVPAVLPAPQQGFRLMDSAAAWQVIDILKDSPRPQGYLSAAAGGRPVAFKTGTSYGYRDA WAVGASPDWVVGVWTGRPDGRPRPGAVGRTAAVPLLLDIFGRLPPDTGPWPSPPAGVLDVRDNRRLPTGLQRFVPGSGTG LPVLAGEPPRILHPQQGATVESLGQQAGEGIALRASGGTAPLRWVVNGLPLPEDQHYWLPDSEGFARLTLVDAAGRSATV QIRIILPQQPALAP
Sequences:
>Translated_734_residues MPPARIMCNGNPPETDFPMPLTQHQPPATQHTARTRPALIRPAFIRAAAAVGISLFCTVMLLLVLDAAFPPDLSRYNRRS VLVTDAEGRLLHAFLSPDGMWRLHTTPHDVDSRYLDMLRTYEDKRFGMHPGVDPLAVLRAAAQLAVSGHVVSGASTLSMQ AARLLQPRPRTLKAKLTEALRAMQLHWRYGSNGVLSIYLTLAPFGSNIEGVRAASLAYFGKEPRRLTTGEAALLVALPQS PTQLRPDRNPLEARKARDKILGRMHAAGIISGRQHTEARTESIPAVRRQMPALASVLALNMRNAAPRREHIATALSLPVQ HAAETLCQRHALSMEQGAATAAVVLHRATRQVRAYVGGKNADASRNYLDLPRALRSPGSTLKPFIYGLAFSEHILHPETL ISDEAHRFGDFSPRNFRRGYQGAVTVREALRDSLNVPAVSVLYALGPDRLVAALRNAGATLAVEGDATLPIALGGAGTTL LDLTTLYAALADGGTALPPQFVPAVLPAPQQGFRLMDSAAAWQVIDILKDSPRPQGYLSAAAGGRPVAFKTGTSYGYRDA WAVGASPDWVVGVWTGRPDGRPRPGAVGRTAAVPLLLDIFGRLPPDTGPWPSPPAGVLDVRDNRRLPTGLQRFVPGSGTG LPVLAGEPPRILHPQQGATVESLGQQAGEGIALRASGGTAPLRWVVNGLPLPEDQHYWLPDSEGFARLTLVDAAGRSATV QIRIILPQQPALAP >Mature_733_residues PPARIMCNGNPPETDFPMPLTQHQPPATQHTARTRPALIRPAFIRAAAAVGISLFCTVMLLLVLDAAFPPDLSRYNRRSV LVTDAEGRLLHAFLSPDGMWRLHTTPHDVDSRYLDMLRTYEDKRFGMHPGVDPLAVLRAAAQLAVSGHVVSGASTLSMQA ARLLQPRPRTLKAKLTEALRAMQLHWRYGSNGVLSIYLTLAPFGSNIEGVRAASLAYFGKEPRRLTTGEAALLVALPQSP TQLRPDRNPLEARKARDKILGRMHAAGIISGRQHTEARTESIPAVRRQMPALASVLALNMRNAAPRREHIATALSLPVQH AAETLCQRHALSMEQGAATAAVVLHRATRQVRAYVGGKNADASRNYLDLPRALRSPGSTLKPFIYGLAFSEHILHPETLI SDEAHRFGDFSPRNFRRGYQGAVTVREALRDSLNVPAVSVLYALGPDRLVAALRNAGATLAVEGDATLPIALGGAGTTLL DLTTLYAALADGGTALPPQFVPAVLPAPQQGFRLMDSAAAWQVIDILKDSPRPQGYLSAAAGGRPVAFKTGTSYGYRDAW AVGASPDWVVGVWTGRPDGRPRPGAVGRTAAVPLLLDIFGRLPPDTGPWPSPPAGVLDVRDNRRLPTGLQRFVPGSGTGL PVLAGEPPRILHPQQGATVESLGQQAGEGIALRASGGTAPLRWVVNGLPLPEDQHYWLPDSEGFARLTLVDAAGRSATVQ IRIILPQQPALAP
Specific function: Cell wall formation. The enzyme has a penicillin- insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a transpeptidase C-terminal domain which may not be functional [H]
COG id: COG4953
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI1788867, Length=657, Percent_Identity=40.1826484018265, Blast_Score=398, Evalue=1e-112, Organism=Escherichia coli, GI87082258, Length=236, Percent_Identity=32.2033898305085, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI1786343, Length=614, Percent_Identity=26.8729641693811, Blast_Score=111, Evalue=2e-25, Organism=Escherichia coli, GI1789601, Length=148, Percent_Identity=31.7567567567568, Blast_Score=67, Evalue=4e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011815 - InterPro: IPR009647 - InterPro: IPR001460 [H]
Pfam domain/function: PF06832 BiPBP_C; PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-
Molecular weight: Translated: 78790; Mature: 78658
Theoretical pI: Translated: 10.61; Mature: 10.61
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.9 %Met (Translated Protein) 2.3 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPPARIMCNGNPPETDFPMPLTQHQPPATQHTARTRPALIRPAFIRAAAAVGISLFCTVM CCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH LLLVLDAAFPPDLSRYNRRSVLVTDAEGRLLHAFLSPDGMWRLHTTPHDVDSRYLDMLRT HHHHHHCCCCCCHHHCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHH YEDKRFGMHPGVDPLAVLRAAAQLAVSGHVVSGASTLSMQAARLLQPRPRTLKAKLTEAL HHHHHCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHH RAMQLHWRYGSNGVLSIYLTLAPFGSNIEGVRAASLAYFGKEPRRLTTGEAALLVALPQS HHHHHEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEEEECCC PTQLRPDRNPLEARKARDKILGRMHAAGIISGRQHTEARTESIPAVRRQMPALASVLALN CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH MRNAAPRREHIATALSLPVQHAAETLCQRHALSMEQGAATAAVVLHRATRQVRAYVGGKN HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCC ADASRNYLDLPRALRSPGSTLKPFIYGLAFSEHILHPETLISDEAHRFGDFSPRNFRRGY CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCHHHHCCC QGAVTVREALRDSLNVPAVSVLYALGPDRLVAALRNAGATLAVEGDATLPIALGGAGTTL CHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCHH LDLTTLYAALADGGTALPPQFVPAVLPAPQQGFRLMDSAAAWQVIDILKDSPRPQGYLSA HHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC AAGGRPVAFKTGTSYGYRDAWAVGASPDWVVGVWTGRPDGRPRPGAVGRTAAVPLLLDIF CCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH GRLPPDTGPWPSPPAGVLDVRDNRRLPTGLQRFVPGSGTGLPVLAGEPPRILHPQQGATV HCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHH ESLGQQAGEGIALRASGGTAPLRWVVNGLPLPEDQHYWLPDSEGFARLTLVDAAGRSATV HHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCCEECCCCCCCEEEEEEECCCCCEEE QIRIILPQQPALAP EEEEEECCCCCCCC >Mature Secondary Structure PPARIMCNGNPPETDFPMPLTQHQPPATQHTARTRPALIRPAFIRAAAAVGISLFCTVM CCCEEEECCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH LLLVLDAAFPPDLSRYNRRSVLVTDAEGRLLHAFLSPDGMWRLHTTPHDVDSRYLDMLRT HHHHHHCCCCCCHHHCCCCEEEEECCCCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHH YEDKRFGMHPGVDPLAVLRAAAQLAVSGHVVSGASTLSMQAARLLQPRPRTLKAKLTEAL HHHHHCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHH RAMQLHWRYGSNGVLSIYLTLAPFGSNIEGVRAASLAYFGKEPRRLTTGEAALLVALPQS HHHHHEEEECCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCCCCEEECCCEEEEEEECCC PTQLRPDRNPLEARKARDKILGRMHAAGIISGRQHTEARTESIPAVRRQMPALASVLALN CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH MRNAAPRREHIATALSLPVQHAAETLCQRHALSMEQGAATAAVVLHRATRQVRAYVGGKN HHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHCCCC ADASRNYLDLPRALRSPGSTLKPFIYGLAFSEHILHPETLISDEAHRFGDFSPRNFRRGY CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHCCHHHHCCCCCCHHHHCCC QGAVTVREALRDSLNVPAVSVLYALGPDRLVAALRNAGATLAVEGDATLPIALGGAGTTL CHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHCCCCEEEECCCCEEEEEECCCCCHH LDLTTLYAALADGGTALPPQFVPAVLPAPQQGFRLMDSAAAWQVIDILKDSPRPQGYLSA HHHHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC AAGGRPVAFKTGTSYGYRDAWAVGASPDWVVGVWTGRPDGRPRPGAVGRTAAVPLLLDIF CCCCCEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHH GRLPPDTGPWPSPPAGVLDVRDNRRLPTGLQRFVPGSGTGLPVLAGEPPRILHPQQGATV HCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHHCCCCCCCCEEECCCCCCCCCCCCCCHH ESLGQQAGEGIALRASGGTAPLRWVVNGLPLPEDQHYWLPDSEGFARLTLVDAAGRSATV HHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCCCEECCCCCCCEEEEEEECCCCCEEE QIRIILPQQPALAP EEEEEECCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 10542235; 9205837; 9278503; 9841666 [H]