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The map label for this gene is yegE [C]

Identifier: 78355258

GI number: 78355258

Start: 191079

End: 192995

Strand: Reverse

Name: yegE [C]

Synonym: Dde_0211

Alternate gene names: 78355258

Gene position: 192995-191079 (Counterclockwise)

Preceding gene: 78355260

Following gene: 78355256

Centisome position: 5.17

GC content: 60.09

Gene sequence:

>1917_bases
ATGAGCATATACGGACACCCCTTTTTACTTCCGGCACAGGCCGCCGCTGCCTGCCTGACCCTGCTGGCAGCCGCGCCCGC
GGTACCGGCCGCTCAGCGCACTGCGGACGTAATGGCCGGCACATGGACATACGGCGGCAGGCCCTACATGCTGCTGCTGG
GCATACTGGTTGTCGTATCCGCCGGTATGGCGGTTACCGGCATGGTCCGGGCCAGAAATGCCGCCCGCCGCGCTGCGCAG
ATGGAAAAACTGCTCCGCCAGCGGCTGGGAGAAACAACCGAATGGGCCGACAGAGAACGCGAAATACGGACGCTCATGCA
CCATGCCGCCATCGGCATCTACCGTTCAACGCTTGACGGTTCGCGCTTTACCGAAGCCAACAAGCATCTTGCGCTGCTGT
ACGGCATGCATGATGAAAAAGAATTTCTGCGCACCGTCACGCCGCTGGATATGCACCCGTCGGGACAAAACCGGCAGGAA
CTCATGCAGAAGCTGCGCCGCGACGGCGTGGTCAGCAGGCAGAAAATCCTGCTGCGCGACAAATCAGGCAGTCTGCGGCA
CGCCATCACGTCCGCGCTCATAAGTTCCCGCAATGAAAGCATCTTCGGGCTTATTTATGACATGACGGACGAACACAACA
GCAAAGAGGAAATGCGCCGCACCGGCGCCATGCTGCAGTCGGTCATTGATGCCATGCCCAACCCGTTCTTTTTTAAAAAT
GCCCGGGGCCGCTATAAGATTGTGAACCGCGCCTTCTGCCGGCTTGTGAACCGCCCTGCCGAAGCGCTGGTGGACCGTAC
GGTCGAAGCATTCGCCTCGCCCGCCATGGCACAGATATACAACGATGCCGACGCAGTGCTGCTGACAGCGGCAGGCCCCG
CCGTGCAGCGCTATGAAACCGTTGTCGAATCGGAAGAAGGCGGCACTGAGGTGCTGCTGTACAAAGAAAGCATATGCGAC
GATAACGGAACCATCACGGGCATAGTGGGCGCAGCGTTTGACATCACATCGCGCAAGGAAACCGAATCGGCCCTGCGGCA
GGCGGAAGAGCGGTACCGCACCATTTTCATGCATGCTCTGGACGGCATTTTCACCTGCACGCCGCAAGGTCTCCTGCTGG
AAGCCAACCCCGCTTTTGCGCGCATGTTCGGTTACGAAAGCCGTGAAACCCTGCTGGAAACCGTTCCGTCCGTCCGCTCG
CTGTGGGTCAGCAGCCAGACACACGACGAAATGATGGGCCTTTTATGCAACCGGCCGCAACTCACGGCGCAGCGTGCCGA
GATGCTGCGCCGCAACGGCGAACACTTCTGGGCGGAAATAAGCTGTCAGGCCTTTTATGACACGCAGGGCGAAGTGACAC
GCATAGAGGGCATCATCTCTGACGTGACGCACCATATGATGCAGGAACGTGAGCTGCGGACACAGGCTTCCACGGACAAA
CTGACCGGCCTCATGAACCGTTACGGCTTTGATGAAGCCTTTGAGCGGCTGCTGGCGCAGGCGCAGCGCAGTTCGCGCAA
GGTGGGCGTGGCGTTCATTGATCTGGACGGGTTCAAGGAGATCAATGACAGATTCGGCCACGACACAGGAGACATGCTGT
TGAAAGAGGTGGCACGCAGACTGCAGCAACGCGTGCGCGAAACCGATATAACGGCCAGACCGGGCGGTGACGAGTTTGCC
GTGCTGTTGTGGGATGTGGGCGGAACCGAAGACCTGCGGCGGCTGGGGGAAAGCCTGCTGGACGCGCTGCGTCCGCCCTA
CCGCTGCGATGCAAATGTCTGTACGCTGACAGCCAGCATAGGGCTGAGCCTGTACCCCGACCACGGGCTGACCGCAGGAA
CCCTGCTGCGGCAGGCTGACCAGGCCATGTATGCGGTAAAAAACGCCGGAAAAAACGCTGTCCGGCTGGCTGTGTGA

Upstream 100 bases:

>100_bases
TACCGGACAGGCTTGAAAAGCTCTCCGCGGGCAGGCCGCCGCTATTCGCGCTGCACGGAAAATGTGCTATTATGACGGCA
AAAGACAGGAGCCGCACCCC

Downstream 100 bases:

>100_bases
CACACCATGGAAAACGGGCGGCAGCCTTTCTGTAAACCGGCCGCCGCCCGCAGGGATTCTCCGGACTTATTTCTTCCAGC
GCGAAGACTGCAGGTCTTCA

Product: diguanylate cyclase with PAS/PAC sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MSIYGHPFLLPAQAAAACLTLLAAAPAVPAAQRTADVMAGTWTYGGRPYMLLLGILVVVSAGMAVTGMVRARNAARRAAQ
MEKLLRQRLGETTEWADREREIRTLMHHAAIGIYRSTLDGSRFTEANKHLALLYGMHDEKEFLRTVTPLDMHPSGQNRQE
LMQKLRRDGVVSRQKILLRDKSGSLRHAITSALISSRNESIFGLIYDMTDEHNSKEEMRRTGAMLQSVIDAMPNPFFFKN
ARGRYKIVNRAFCRLVNRPAEALVDRTVEAFASPAMAQIYNDADAVLLTAAGPAVQRYETVVESEEGGTEVLLYKESICD
DNGTITGIVGAAFDITSRKETESALRQAEERYRTIFMHALDGIFTCTPQGLLLEANPAFARMFGYESRETLLETVPSVRS
LWVSSQTHDEMMGLLCNRPQLTAQRAEMLRRNGEHFWAEISCQAFYDTQGEVTRIEGIISDVTHHMMQERELRTQASTDK
LTGLMNRYGFDEAFERLLAQAQRSSRKVGVAFIDLDGFKEINDRFGHDTGDMLLKEVARRLQQRVRETDITARPGGDEFA
VLLWDVGGTEDLRRLGESLLDALRPPYRCDANVCTLTASIGLSLYPDHGLTAGTLLRQADQAMYAVKNAGKNAVRLAV

Sequences:

>Translated_638_residues
MSIYGHPFLLPAQAAAACLTLLAAAPAVPAAQRTADVMAGTWTYGGRPYMLLLGILVVVSAGMAVTGMVRARNAARRAAQ
MEKLLRQRLGETTEWADREREIRTLMHHAAIGIYRSTLDGSRFTEANKHLALLYGMHDEKEFLRTVTPLDMHPSGQNRQE
LMQKLRRDGVVSRQKILLRDKSGSLRHAITSALISSRNESIFGLIYDMTDEHNSKEEMRRTGAMLQSVIDAMPNPFFFKN
ARGRYKIVNRAFCRLVNRPAEALVDRTVEAFASPAMAQIYNDADAVLLTAAGPAVQRYETVVESEEGGTEVLLYKESICD
DNGTITGIVGAAFDITSRKETESALRQAEERYRTIFMHALDGIFTCTPQGLLLEANPAFARMFGYESRETLLETVPSVRS
LWVSSQTHDEMMGLLCNRPQLTAQRAEMLRRNGEHFWAEISCQAFYDTQGEVTRIEGIISDVTHHMMQERELRTQASTDK
LTGLMNRYGFDEAFERLLAQAQRSSRKVGVAFIDLDGFKEINDRFGHDTGDMLLKEVARRLQQRVRETDITARPGGDEFA
VLLWDVGGTEDLRRLGESLLDALRPPYRCDANVCTLTASIGLSLYPDHGLTAGTLLRQADQAMYAVKNAGKNAVRLAV
>Mature_637_residues
SIYGHPFLLPAQAAAACLTLLAAAPAVPAAQRTADVMAGTWTYGGRPYMLLLGILVVVSAGMAVTGMVRARNAARRAAQM
EKLLRQRLGETTEWADREREIRTLMHHAAIGIYRSTLDGSRFTEANKHLALLYGMHDEKEFLRTVTPLDMHPSGQNRQEL
MQKLRRDGVVSRQKILLRDKSGSLRHAITSALISSRNESIFGLIYDMTDEHNSKEEMRRTGAMLQSVIDAMPNPFFFKNA
RGRYKIVNRAFCRLVNRPAEALVDRTVEAFASPAMAQIYNDADAVLLTAAGPAVQRYETVVESEEGGTEVLLYKESICDD
NGTITGIVGAAFDITSRKETESALRQAEERYRTIFMHALDGIFTCTPQGLLLEANPAFARMFGYESRETLLETVPSVRSL
WVSSQTHDEMMGLLCNRPQLTAQRAEMLRRNGEHFWAEISCQAFYDTQGEVTRIEGIISDVTHHMMQERELRTQASTDKL
TGLMNRYGFDEAFERLLAQAQRSSRKVGVAFIDLDGFKEINDRFGHDTGDMLLKEVARRLQQRVRETDITARPGGDEFAV
LLWDVGGTEDLRRLGESLLDALRPPYRCDANVCTLTASIGLSLYPDHGLTAGTLLRQADQAMYAVKNAGKNAVRLAV

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=322, Percent_Identity=28.8819875776398, Blast_Score=116, Evalue=4e-27,
Organism=Escherichia coli, GI1787541, Length=172, Percent_Identity=35.4651162790698, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI145693134, Length=171, Percent_Identity=35.0877192982456, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87081977, Length=157, Percent_Identity=37.5796178343949, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787262, Length=189, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788956, Length=172, Percent_Identity=33.7209302325581, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786584, Length=176, Percent_Identity=32.3863636363636, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=179, Percent_Identity=31.8435754189944, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787802, Length=178, Percent_Identity=30.8988764044944, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=176, Percent_Identity=33.5227272727273, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=88, Percent_Identity=37.5, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788085, Length=204, Percent_Identity=27.9411764705882, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787816, Length=164, Percent_Identity=29.2682926829268, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71193; Mature: 71062

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIYGHPFLLPAQAAAACLTLLAAAPAVPAAQRTADVMAGTWTYGGRPYMLLLGILVVVS
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AGMAVTGMVRARNAARRAAQMEKLLRQRLGETTEWADREREIRTLMHHAAIGIYRSTLDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRFTEANKHLALLYGMHDEKEFLRTVTPLDMHPSGQNRQELMQKLRRDGVVSRQKILLRD
CHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHEEEC
KSGSLRHAITSALISSRNESIFGLIYDMTDEHNSKEEMRRTGAMLQSVIDAMPNPFFFKN
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
ARGRYKIVNRAFCRLVNRPAEALVDRTVEAFASPAMAQIYNDADAVLLTAAGPAVQRYET
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCHHHHHHHH
VVESEEGGTEVLLYKESICDDNGTITGIVGAAFDITSRKETESALRQAEERYRTIFMHAL
HHHCCCCCCEEEEEEHHCCCCCCCEEEEEHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
DGIFTCTPQGLLLEANPAFARMFGYESRETLLETVPSVRSLWVSSQTHDEMMGLLCNRPQ
CCCEEECCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
LTAQRAEMLRRNGEHFWAEISCQAFYDTQGEVTRIEGIISDVTHHMMQERELRTQASTDK
HHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLMNRYGFDEAFERLLAQAQRSSRKVGVAFIDLDGFKEINDRFGHDTGDMLLKEVARR
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHH
LQQRVRETDITARPGGDEFAVLLWDVGGTEDLRRLGESLLDALRPPYRCDANVCTLTASI
HHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GLSLYPDHGLTAGTLLRQADQAMYAVKNAGKNAVRLAV
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure 
SIYGHPFLLPAQAAAACLTLLAAAPAVPAAQRTADVMAGTWTYGGRPYMLLLGILVVVS
CCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
AGMAVTGMVRARNAARRAAQMEKLLRQRLGETTEWADREREIRTLMHHAAIGIYRSTLDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
SRFTEANKHLALLYGMHDEKEFLRTVTPLDMHPSGQNRQELMQKLRRDGVVSRQKILLRD
CHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHEEEC
KSGSLRHAITSALISSRNESIFGLIYDMTDEHNSKEEMRRTGAMLQSVIDAMPNPFFFKN
CCCCHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEC
ARGRYKIVNRAFCRLVNRPAEALVDRTVEAFASPAMAQIYNDADAVLLTAAGPAVQRYET
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCEEEEEECCHHHHHHHH
VVESEEGGTEVLLYKESICDDNGTITGIVGAAFDITSRKETESALRQAEERYRTIFMHAL
HHHCCCCCCEEEEEEHHCCCCCCCEEEEEHHHEECCCCHHHHHHHHHHHHHHHHHHHHHH
DGIFTCTPQGLLLEANPAFARMFGYESRETLLETVPSVRSLWVSSQTHDEMMGLLCNRPQ
CCCEEECCCCEEEECCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
LTAQRAEMLRRNGEHFWAEISCQAFYDTQGEVTRIEGIISDVTHHMMQERELRTQASTDK
HHHHHHHHHHHCCCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTGLMNRYGFDEAFERLLAQAQRSSRKVGVAFIDLDGFKEINDRFGHDTGDMLLKEVARR
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHH
LQQRVRETDITARPGGDEFAVLLWDVGGTEDLRRLGESLLDALRPPYRCDANVCTLTASI
HHHHHHHCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GLSLYPDHGLTAGTLLRQADQAMYAVKNAGKNAVRLAV
CCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]