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The map label for this gene is lytT [H]

Identifier: 78355208

GI number: 78355208

Start: 148093

End: 148905

Strand: Reverse

Name: lytT [H]

Synonym: Dde_0161

Alternate gene names: 78355208

Gene position: 148905-148093 (Counterclockwise)

Preceding gene: 78355212

Following gene: 78355207

Centisome position: 3.99

GC content: 56.95

Gene sequence:

>813_bases
ATGACAATTCGCTGCATCGTTGTGGATGATGAACCGCCTGCACGGGATGAGATGGTCTATCTGCTTTCCCGCTTTGCAGA
TGTGCAGGTAGCCGGCACTGCGGATTCCGCGGAGCAGGCGCTTGCGCTTATTGCGCAGCAGAAGCCCGACCTTGTGTTTC
TGGACATCCAGATGTACGGCCACAACGGTTTTTATGTTGTGGAGCAGTTGCTGGATTATCCCGAACCTCCGCTTGTTGTT
TTTGCCACTGCGTACGACCAGTACGCCATCCGCGCTTTTGATGAAAATGCCGTGGACTACCTGCTTAAGCCCATAGAGGA
AAAGCGGCTGGCCAAAAGCCTTGACCGTGTGCGCGAAGCTCTGGCTGCCCGCACGGAACAGGAGCAGGACAGCCGGACGC
AGACCGCTCCGCCGCTGCATGACGACATCCGTCTTGGCAGACTGCTTGAACAGATGGGCAGGCGCACTGTGCTCACGCGG
GTAGCAGTGGAACGCGGCGGGCGCATTGTGCTGCTGCAGCCTGACGAGGTTTTTTTCATTCAGGCTCAGGGCAAACGGAT
CTGGGCACACACAACCGAGGGTATGGCTCCGTGCCACGGCGTGACAAATCTGCAAAAGCTGGAAGAAAAACTCGCCGGGC
ATGATTTTTTCCGCGCCACCCGCGGAGAACTGATCAACATGCAGCATGTCCGCGAATTTTCGCCCTGGATGCACGGCAAA
TACAACATTGTCATGAGCGACCCCGGCCAGACAGAAATCACCGTCAACCGCAGCAGGGTCAAAGATTTCAAGGAACGGCT
GGGGCTGGTCTGA

Upstream 100 bases:

>100_bases
CAACTCGGGTGTGTGTACACCGCGCCCACGCCGCGGGCAAGCGGCACACCGTTACCGGCCCCTATGGACAAGCTGCTGCA
CCGGCATTAGGGTCAGATGC

Downstream 100 bases:

>100_bases
TAGCGGTGACCGCCCCGTATTGCCGCAGCGGAGAAACAGCATGACAACGGGCATTCTGCTCATAACGCTTATCGAGCGTT
TCGGCCTCATGGTTGCCGGA

Product: LytR/AlgR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTIRCIVVDDEPPARDEMVYLLSRFADVQVAGTADSAEQALALIAQQKPDLVFLDIQMYGHNGFYVVEQLLDYPEPPLVV
FATAYDQYAIRAFDENAVDYLLKPIEEKRLAKSLDRVREALAARTEQEQDSRTQTAPPLHDDIRLGRLLEQMGRRTVLTR
VAVERGGRIVLLQPDEVFFIQAQGKRIWAHTTEGMAPCHGVTNLQKLEEKLAGHDFFRATRGELINMQHVREFSPWMHGK
YNIVMSDPGQTEITVNRSRVKDFKERLGLV

Sequences:

>Translated_270_residues
MTIRCIVVDDEPPARDEMVYLLSRFADVQVAGTADSAEQALALIAQQKPDLVFLDIQMYGHNGFYVVEQLLDYPEPPLVV
FATAYDQYAIRAFDENAVDYLLKPIEEKRLAKSLDRVREALAARTEQEQDSRTQTAPPLHDDIRLGRLLEQMGRRTVLTR
VAVERGGRIVLLQPDEVFFIQAQGKRIWAHTTEGMAPCHGVTNLQKLEEKLAGHDFFRATRGELINMQHVREFSPWMHGK
YNIVMSDPGQTEITVNRSRVKDFKERLGLV
>Mature_269_residues
TIRCIVVDDEPPARDEMVYLLSRFADVQVAGTADSAEQALALIAQQKPDLVFLDIQMYGHNGFYVVEQLLDYPEPPLVVF
ATAYDQYAIRAFDENAVDYLLKPIEEKRLAKSLDRVREALAARTEQEQDSRTQTAPPLHDDIRLGRLLEQMGRRTVLTRV
AVERGGRIVLLQPDEVFFIQAQGKRIWAHTTEGMAPCHGVTNLQKLEEKLAGHDFFRATRGELINMQHVREFSPWMHGKY
NIVMSDPGQTEITVNRSRVKDFKERLGLV

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=267, Percent_Identity=31.4606741573034, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788724, Length=269, Percent_Identity=25.6505576208178, Blast_Score=115, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30822; Mature: 30690

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRCIVVDDEPPARDEMVYLLSRFADVQVAGTADSAEQALALIAQQKPDLVFLDIQMYG
CEEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEC
HNGFYVVEQLLDYPEPPLVVFATAYDQYAIRAFDENAVDYLLKPIEEKRLAKSLDRVREA
CCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAARTEQEQDSRTQTAPPLHDDIRLGRLLEQMGRRTVLTRVAVERGGRIVLLQPDEVFFI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCEEEE
QAQGKRIWAHTTEGMAPCHGVTNLQKLEEKLAGHDFFRATRGELINMQHVREFSPWMHGK
EECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCE
YNIVMSDPGQTEITVNRSRVKDFKERLGLV
EEEEECCCCCEEEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIRCIVVDDEPPARDEMVYLLSRFADVQVAGTADSAEQALALIAQQKPDLVFLDIQMYG
EEEEEEECCCCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCCEEEEEEEEEC
HNGFYVVEQLLDYPEPPLVVFATAYDQYAIRAFDENAVDYLLKPIEEKRLAKSLDRVREA
CCCHHHHHHHHCCCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAARTEQEQDSRTQTAPPLHDDIRLGRLLEQMGRRTVLTRVAVERGGRIVLLQPDEVFFI
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHCCCEEEEECCCCEEEE
QAQGKRIWAHTTEGMAPCHGVTNLQKLEEKLAGHDFFRATRGELINMQHVREFSPWMHGK
EECCCEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHCCCCCCE
YNIVMSDPGQTEITVNRSRVKDFKERLGLV
EEEEECCCCCEEEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]