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The map label for this gene is fruR [H]

Identifier: 78355177

GI number: 78355177

Start: 122008

End: 122853

Strand: Reverse

Name: fruR [H]

Synonym: Dde_0130

Alternate gene names: 78355177

Gene position: 122853-122008 (Counterclockwise)

Preceding gene: 78355178

Following gene: 78355176

Centisome position: 3.29

GC content: 60.17

Gene sequence:

>846_bases
ATGACCGGAGACGCTACGCCGCCGGTCGGGCTGCGTTTTGCACAAGACAAAACGCACGAGGTGTTCATGAAGCGATACAG
GCACACGCAGATTCTCGCCCTGCTGGAAACACGCTCCGCCATACGGGCAACCGAGGCGGCGGAGATGCTGGGCGTTTCTG
TGGGAACAATCCGGCGGGACATGGCCGAACTGGAAGCCGGAGGCTACCTGAACAGAACGCATGGCGGAGCCTTTGCCGCC
ATCGAGGGCGAAGCGGGCTTCATGCGCCGCACCTGCTGGAACAGAGACAAAAAGCGTGTCATCGGACAGGCTGCGGCAGC
ACATATTTCTTCAGGCAGTGTGGTCTTCATCGACGGCGGAACAACGCCGGAGGCCATGCTGCCGTTTCTTGTGGAAAAAA
CCTCGCTTACGGTGGTCACCTGCGGGCTGAACATTGCCCTGCAGCTGCTGCGCTGGCCTTACATCAGCACCATTCTGCTG
GGCGGCGAAGTACATGCGGAATCACGCACAGTGACCGGCACCCTGCCGGTGACACAGCTGGACTCGTTCGGCATGCGCTT
TGACATGGCCGTCATAGCCACCGCGGGCATTAGCGCGGAACACGGTGCCACCAACCGCATGCTGGAACGGCTGGCGCTGA
AGCAGCTGGTACTGCGCAACAGCGCTTCAAGCATTCTGGTAGGCGACAGTTCCAAAGTGAACTGCGCATTTCTGGGCAGA
GTAGCGCCGCTGTCGGCGTTTTCGCTGTGTATTATGGACGACGACCTGACAGATGAGCAGAAAGCGAAGCTGTCGGAAGC
CGGGCGATTCGAATTCGTGCCTCTGGAAGGGAGCAGACGGCGGTGA

Upstream 100 bases:

>100_bases
CAGCACACTTCTTCCGCTGTTAAAAACGACAGAAACAGGTAAAAAACGATCAAAAGCGATCATTCTTTGATCGTATTGTA
CCGGTTGCTAGGGTGCAGCC

Downstream 100 bases:

>100_bases
CAGGCCGCGCCGGAAGCTGCGGCCGCCTGCGGATTCGCTTTGCCTGCCTTATGGCGGCGCACACAGCTGCGCCGCGGTCA
CGCCAACCCCGGCTGACAGA

Product: regulatory protein, DeoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTGDATPPVGLRFAQDKTHEVFMKRYRHTQILALLETRSAIRATEAAEMLGVSVGTIRRDMAELEAGGYLNRTHGGAFAA
IEGEAGFMRRTCWNRDKKRVIGQAAAAHISSGSVVFIDGGTTPEAMLPFLVEKTSLTVVTCGLNIALQLLRWPYISTILL
GGEVHAESRTVTGTLPVTQLDSFGMRFDMAVIATAGISAEHGATNRMLERLALKQLVLRNSASSILVGDSSKVNCAFLGR
VAPLSAFSLCIMDDDLTDEQKAKLSEAGRFEFVPLEGSRRR

Sequences:

>Translated_281_residues
MTGDATPPVGLRFAQDKTHEVFMKRYRHTQILALLETRSAIRATEAAEMLGVSVGTIRRDMAELEAGGYLNRTHGGAFAA
IEGEAGFMRRTCWNRDKKRVIGQAAAAHISSGSVVFIDGGTTPEAMLPFLVEKTSLTVVTCGLNIALQLLRWPYISTILL
GGEVHAESRTVTGTLPVTQLDSFGMRFDMAVIATAGISAEHGATNRMLERLALKQLVLRNSASSILVGDSSKVNCAFLGR
VAPLSAFSLCIMDDDLTDEQKAKLSEAGRFEFVPLEGSRRR
>Mature_280_residues
TGDATPPVGLRFAQDKTHEVFMKRYRHTQILALLETRSAIRATEAAEMLGVSVGTIRRDMAELEAGGYLNRTHGGAFAAI
EGEAGFMRRTCWNRDKKRVIGQAAAAHISSGSVVFIDGGTTPEAMLPFLVEKTSLTVVTCGLNIALQLLRWPYISTILLG
GEVHAESRTVTGTLPVTQLDSFGMRFDMAVIATAGISAEHGATNRMLERLALKQLVLRNSASSILVGDSSKVNCAFLGRV
APLSAFSLCIMDDDLTDEQKAKLSEAGRFEFVPLEGSRRR

Specific function: Repressor Of The Glycerol-3-Phosphate Regulon. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=233, Percent_Identity=30.0429184549356, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789519, Length=246, Percent_Identity=26.0162601626016, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1789059, Length=236, Percent_Identity=30.0847457627119, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787540, Length=245, Percent_Identity=29.7959183673469, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87082344, Length=225, Percent_Identity=27.1111111111111, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI226510968, Length=234, Percent_Identity=29.9145299145299, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787063, Length=252, Percent_Identity=26.5873015873016, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788069, Length=208, Percent_Identity=24.5192307692308, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790753, Length=253, Percent_Identity=24.901185770751, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 30445; Mature: 30314

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDATPPVGLRFAQDKTHEVFMKRYRHTQILALLETRSAIRATEAAEMLGVSVGTIRRD
CCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
MAELEAGGYLNRTHGGAFAAIEGEAGFMRRTCWNRDKKRVIGQAAAAHISSGSVVFIDGG
HHHHHCCCCEECCCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECC
TTPEAMLPFLVEKTSLTVVTCGLNIALQLLRWPYISTILLGGEVHAESRTVTGTLPVTQL
CCHHHHHHHHHCCCCEEEEEECHHHHHHHHHCHHHHHEEECCEEECCCEEEEECCCHHHH
DSFGMRFDMAVIATAGISAEHGATNRMLERLALKQLVLRNSASSILVGDSSKVNCAFLGR
HCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECC
VAPLSAFSLCIMDDDLTDEQKAKLSEAGRFEFVPLEGSRRR
CCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure 
TGDATPPVGLRFAQDKTHEVFMKRYRHTQILALLETRSAIRATEAAEMLGVSVGTIRRD
CCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHH
MAELEAGGYLNRTHGGAFAAIEGEAGFMRRTCWNRDKKRVIGQAAAAHISSGSVVFIDGG
HHHHHCCCCEECCCCCEEEEEECCCCHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEECC
TTPEAMLPFLVEKTSLTVVTCGLNIALQLLRWPYISTILLGGEVHAESRTVTGTLPVTQL
CCHHHHHHHHHCCCCEEEEEECHHHHHHHHHCHHHHHEEECCEEECCCEEEEECCCHHHH
DSFGMRFDMAVIATAGISAEHGATNRMLERLALKQLVLRNSASSILVGDSSKVNCAFLGR
HCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECC
VAPLSAFSLCIMDDDLTDEQKAKLSEAGRFEFVPLEGSRRR
CCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]