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The map label for this gene is hrcA [H]

Identifier: 78224717

GI number: 78224717

Start: 3967975

End: 3969006

Strand: Reverse

Name: hrcA [H]

Synonym: Gmet_3534

Alternate gene names: 78224717

Gene position: 3969006-3967975 (Counterclockwise)

Preceding gene: 78224718

Following gene: 78224716

Centisome position: 99.29

GC content: 62.31

Gene sequence:

>1032_bases
ATGGGAGAAGGGCTTTCAGAGCGCAATAAAAAGATCCTTGAGGCGATCATCGAGGACTATATTGTGACCGCCGAGCCGGT
GGGAAGCCGGGCCGTCACGCGGCGGCACGGTCTCAACCTGTCGCCGGCCACGGTCCGCAACGCCATGGCCGATCTGGAGG
AGATGGGGCTCCTTACCTCGCCCCACACCTCTGCCGGCCGTGTTCCCACTGACCGGGCGTACCGTTTTTACGTGGATTCC
CTTCTGGCGGTGGGGCGCATCGACAAGGCCGAGCGGGAGCGGATACGGAAGCGCTACACCGGCGCGGGGCGCGACATGGG
TGCGGTCCTCCACGAGACGACCCGGCTCCTGTCGTCGGTTTCCCACTACATGGGGATTGTCCTAGCTCCCCGCTTCTCCT
CCACCACCCTCCGGCACATGGAATTCGTGAAGCTGGGGGGGCGCCGGATCCTGGCCATCCTGGTGGCCGATAACGGCGCG
GTCCAGAACCGGCTCATCGAGTCAGAGGAAGAGTTCGCCGAGGCCGACCTGGTCCGGATGTCCAACTACCTGAACGAGCT
TCTTCAGGGGCTTCCCGTCGCCCAGGTGCGGACCCGTATCCTGGAGGAGATGCGGAACGAAAAGGTCCTCTACGACACGC
TCTTCTCACGGGCGCTCAAACTTTCGGAGCAGACCATCGTGGAGGGTAGCGCCCAGATCTTCATGGAAGGGCAGACCAAC
ATTCTGGATCAGCCTGAATTCGCCGATGTGGGGCGCATGAAGGATGTGTTCCGGGCTTTCGAGGAGAAGAACCAGCTGGT
GAACCTCCTGGACCGCTGCATCTCGGCCCAGGGAGTCCAGATTTTCATCGGTTCCGAGACCCACCTGAACCACATGGAGG
GGTTGAGCGTCATCACCTCCGCCTATGTGTCGGGGAAAAACACCCTCGGCGTCCTCGGGGTGATCGGCCCGACCCGCATG
GGGTACGGCAAGGTGATCCCCATCGTCGACTACACCGCGAAGCTTGTGAGCAAGCTGCTCGAAGACGAGTAG

Upstream 100 bases:

>100_bases
AAATCTCCGGAAATCTCCTTGACAAAGAAGAGGGGCGTTGTTACCTTTACCCCGTTAGCACTCACCAACTCTGAGTGCTA
ATCTTCTTTGTGGGGTCGGT

Downstream 100 bases:

>100_bases
AGTAAGAAAGGAAAACCATCGTGGACAAAAAAAAGCACGGCTCCCACGCAGGAGCGCACCATACCGATGAGCCCGCAGCC
GAAACCGTGGCCCCGGCAGC

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGEGLSERNKKILEAIIEDYIVTAEPVGSRAVTRRHGLNLSPATVRNAMADLEEMGLLTSPHTSAGRVPTDRAYRFYVDS
LLAVGRIDKAERERIRKRYTGAGRDMGAVLHETTRLLSSVSHYMGIVLAPRFSSTTLRHMEFVKLGGRRILAILVADNGA
VQNRLIESEEEFAEADLVRMSNYLNELLQGLPVAQVRTRILEEMRNEKVLYDTLFSRALKLSEQTIVEGSAQIFMEGQTN
ILDQPEFADVGRMKDVFRAFEEKNQLVNLLDRCISAQGVQIFIGSETHLNHMEGLSVITSAYVSGKNTLGVLGVIGPTRM
GYGKVIPIVDYTAKLVSKLLEDE

Sequences:

>Translated_343_residues
MGEGLSERNKKILEAIIEDYIVTAEPVGSRAVTRRHGLNLSPATVRNAMADLEEMGLLTSPHTSAGRVPTDRAYRFYVDS
LLAVGRIDKAERERIRKRYTGAGRDMGAVLHETTRLLSSVSHYMGIVLAPRFSSTTLRHMEFVKLGGRRILAILVADNGA
VQNRLIESEEEFAEADLVRMSNYLNELLQGLPVAQVRTRILEEMRNEKVLYDTLFSRALKLSEQTIVEGSAQIFMEGQTN
ILDQPEFADVGRMKDVFRAFEEKNQLVNLLDRCISAQGVQIFIGSETHLNHMEGLSVITSAYVSGKNTLGVLGVIGPTRM
GYGKVIPIVDYTAKLVSKLLEDE
>Mature_342_residues
GEGLSERNKKILEAIIEDYIVTAEPVGSRAVTRRHGLNLSPATVRNAMADLEEMGLLTSPHTSAGRVPTDRAYRFYVDSL
LAVGRIDKAERERIRKRYTGAGRDMGAVLHETTRLLSSVSHYMGIVLAPRFSSTTLRHMEFVKLGGRRILAILVADNGAV
QNRLIESEEEFAEADLVRMSNYLNELLQGLPVAQVRTRILEEMRNEKVLYDTLFSRALKLSEQTIVEGSAQIFMEGQTNI
LDQPEFADVGRMKDVFRAFEEKNQLVNLLDRCISAQGVQIFIGSETHLNHMEGLSVITSAYVSGKNTLGVLGVIGPTRMG
YGKVIPIVDYTAKLVSKLLEDE

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005104
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF03444 DUF293; PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38185; Mature: 38053

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEGLSERNKKILEAIIEDYIVTAEPVGSRAVTRRHGLNLSPATVRNAMADLEEMGLLTS
CCCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PHTSAGRVPTDRAYRFYVDSLLAVGRIDKAERERIRKRYTGAGRDMGAVLHETTRLLSSV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SHYMGIVLAPRFSSTTLRHMEFVKLGGRRILAILVADNGAVQNRLIESEEEFAEADLVRM
HHHHHEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SNYLNELLQGLPVAQVRTRILEEMRNEKVLYDTLFSRALKLSEQTIVEGSAQIFMEGQTN
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ILDQPEFADVGRMKDVFRAFEEKNQLVNLLDRCISAQGVQIFIGSETHLNHMEGLSVITS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYVSGKNTLGVLGVIGPTRMGYGKVIPIVDYTAKLVSKLLEDE
HHHCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GEGLSERNKKILEAIIEDYIVTAEPVGSRAVTRRHGLNLSPATVRNAMADLEEMGLLTS
CCCCCHHHHHHHHHHHHHHEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCC
PHTSAGRVPTDRAYRFYVDSLLAVGRIDKAERERIRKRYTGAGRDMGAVLHETTRLLSSV
CCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SHYMGIVLAPRFSSTTLRHMEFVKLGGRRILAILVADNGAVQNRLIESEEEFAEADLVRM
HHHHHEEECCCCCCHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
SNYLNELLQGLPVAQVRTRILEEMRNEKVLYDTLFSRALKLSEQTIVEGSAQIFMEGQTN
HHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
ILDQPEFADVGRMKDVFRAFEEKNQLVNLLDRCISAQGVQIFIGSETHLNHMEGLSVITS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHH
AYVSGKNTLGVLGVIGPTRMGYGKVIPIVDYTAKLVSKLLEDE
HHHCCCCCEEEEEECCCCCCCCCCEEHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA