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The map label for this gene is nuoC

Identifier: 78224543

GI number: 78224543

Start: 3771184

End: 3771672

Strand: Reverse

Name: nuoC

Synonym: Gmet_3353

Alternate gene names: 78224543

Gene position: 3771672-3771184 (Counterclockwise)

Preceding gene: 78224544

Following gene: 78224542

Centisome position: 94.35

GC content: 51.12

Gene sequence:

>489_bases
ATGGCTGAAACTAATCGCGCAGTAATAAAGCTCAGGGAAAAATTTTCCGCTTCCGTGCTTGATGTGAAAGAGTTCCGCGG
AGAGGTGACGGTTACGGTGAAGCGTGAGGACATTGTTGAAATTTGCAATTTCCTCAAGTCGTCGCTTGCCTATAATCTCT
GTACCGACGTAACCGCGGTGGACTATCTGGGGAAGCAAGAGCCACGCTTTATGGTAGTTTACAATCTTTATTCGATTCCG
AATAAAGACCGCCTCAGGGTTAAGGCGGGGGTTCCGGAGGCTGGCTGCTCCATTGATACGGTTTCCTGCGTCTGGAGCGC
GGCCAATTGGTTGGAGCGTGAAGTTTACGATTTGATGGGTGTGGTCTTCAATAATCACCCAGATCTTCGTCGGATACTGA
TGACTGATGACTGGGTCGGCCATCCGCTTCGGAAGGATTATCCGCTGCAGGGGCCTGGTCGTGAGCCTTACAAAGGGCGG
TTGTCGTAG

Upstream 100 bases:

>100_bases
ATCATGAAGGATAAGAACTCCTTTGGTTCTACTATCGGTCTTGGCCAGCGACTCGAGTCGGCGGCGTGACCATATCAACT
AGGTAAGGGAGCCAACGGTT

Downstream 100 bases:

>100_bases
CGATACGGATTATTTGAGCGAAATTAACCTACTCTAGAGAGAAGAATACAGAGGCGCGCAATGGCTAGTACTGAGATTAT
GACAGTCAACATGGGGCCAC

Product: NADH (or F420H2) dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MAETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAVDYLGKQEPRFMVVYNLYSIP
NKDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMGVVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGR
LS

Sequences:

>Translated_162_residues
MAETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAVDYLGKQEPRFMVVYNLYSIP
NKDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMGVVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGR
LS
>Mature_161_residues
AETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAVDYLGKQEPRFMVVYNLYSIPN
KDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMGVVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGRL
S

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family

Homologues:

Organism=Homo sapiens, GI4758788, Length=126, Percent_Identity=42.0634920634921, Blast_Score=101, Evalue=3e-22,
Organism=Escherichia coli, GI145693162, Length=157, Percent_Identity=35.031847133758, Blast_Score=99, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563621, Length=126, Percent_Identity=42.0634920634921, Blast_Score=99, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71990788, Length=126, Percent_Identity=42.0634920634921, Blast_Score=99, Evalue=9e-22,
Organism=Drosophila melanogaster, GI24656494, Length=126, Percent_Identity=42.0634920634921, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUOC_GEOMG (Q39QA9)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386290.1
- ProteinModelPortal:   Q39QA9
- SMR:   Q39QA9
- STRING:   Q39QA9
- GeneID:   3740668
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3353
- NMPDR:   fig|269799.3.peg.3328
- eggNOG:   COG0852
- HOGENOM:   HBG727675
- OMA:   REPYKGR
- ProtClustDB:   CLSK827763
- BioCyc:   GMET269799:GMET_3353-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01357
- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581
- TIGRFAMs:   TIGR01961

Pfam domain/function: PF00329 Complex1_30kDa

EC number: =1.6.99.5

Molecular weight: Translated: 18516; Mature: 18384

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAV
CCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
DYLGKQEPRFMVVYNLYSIPNKDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMG
HHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGRLS
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AETNRAVIKLREKFSASVLDVKEFRGEVTVTVKREDIVEICNFLKSSLAYNLCTDVTAV
CCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHH
DYLGKQEPRFMVVYNLYSIPNKDRLRVKAGVPEAGCSIDTVSCVWSAANWLEREVYDLMG
HHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VVFNNHPDLRRILMTDDWVGHPLRKDYPLQGPGREPYKGRLS
HHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA