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The map label for this gene is comF [H]

Identifier: 78224524

GI number: 78224524

Start: 3747516

End: 3748244

Strand: Reverse

Name: comF [H]

Synonym: Gmet_3333

Alternate gene names: 78224524

Gene position: 3748244-3747516 (Counterclockwise)

Preceding gene: 78224525

Following gene: 78224523

Centisome position: 93.77

GC content: 69.41

Gene sequence:

>729_bases
GTGGAACTCCTCCGGGCGTTTCTCGACGTCCTCTTCCCGCCCCTCTGCCACCTGTGCAAGGCGCCGGTGCCCGGGGCCGG
CCCGCTCCATCTCTGCGATGCCTGCCTTGGGGCCATGACCCCCATCACCTCCCCCCTCTGCCCGGTCTGCGGCGTACCTC
ACCGGACCGAGGGGGGGATCGACCACCTTTGCGGTTCCTGTATGCTCACCCCGCCTCCCTTCGACGGGGTCCGGGGGGCG
CTCCTCTTCGACGGCCCTCTCCAGGAGTTGATCCACCGTCACAAGTACGGCCACAAGGTCCACCTGCGCCGCCCCCTGGC
CCTCCTTGCCATTCGGCATCTCACCCCCTTTGTCCAATCCGTCGCCCCCGATGTAATCATTCCCGTCCCTCTCCACCGTT
CGCGTCTGCGGGAGCGGGGGTTCAACCAGGCGGTTCTCGTGGGTGCCGTCCTGTCCCGCGAGTGGCGCCTGCCGCTCCTG
CGGCACACCCTCCGTCGTGTCCGTCCCACCGTTGCCCAGGTGACCCTTTCCGCCCGGGAGCGCCGGGCCAACGTCCGGGG
GGCCTTCGCCGTTTCCGGTCCCGCCGGCATCGCGGGAAGGCGTGTCCTCCTCATGGATGACGTTGTCACCACCGGTAGCA
CAGTGGCGGAGTGCGCCCGGGTGCTCAAGGATGCCGGCGCCTCGGCTGTATTCGTCATCACGGTTGCGCTGGCTCCGCCG
GGGCGCTAG

Upstream 100 bases:

>100_bases
ACTCCCCCGACCGGATCTGCCGCATCACCACAGTCATCGACCGCAAGCCCCGCCTCACCGACCTGCGGGTGCTGGTGGTG
AACGAGGAGATGGGGTTCTA

Downstream 100 bases:

>100_bases
ATCGACGGCCGCAAGAAGAGGCATGTCCGCAGTTAAGGAAATATCGTTATAGTATCGCGAATGGTCTTCGCATAAACCTA
CTTGGATTGCGGAGTATTAT

Product: phosphoribosyltransferase

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MELLRAFLDVLFPPLCHLCKAPVPGAGPLHLCDACLGAMTPITSPLCPVCGVPHRTEGGIDHLCGSCMLTPPPFDGVRGA
LLFDGPLQELIHRHKYGHKVHLRRPLALLAIRHLTPFVQSVAPDVIIPVPLHRSRLRERGFNQAVLVGAVLSREWRLPLL
RHTLRRVRPTVAQVTLSARERRANVRGAFAVSGPAGIAGRRVLLMDDVVTTGSTVAECARVLKDAGASAVFVITVALAPP
GR

Sequences:

>Translated_242_residues
MELLRAFLDVLFPPLCHLCKAPVPGAGPLHLCDACLGAMTPITSPLCPVCGVPHRTEGGIDHLCGSCMLTPPPFDGVRGA
LLFDGPLQELIHRHKYGHKVHLRRPLALLAIRHLTPFVQSVAPDVIIPVPLHRSRLRERGFNQAVLVGAVLSREWRLPLL
RHTLRRVRPTVAQVTLSARERRANVRGAFAVSGPAGIAGRRVLLMDDVVTTGSTVAECARVLKDAGASAVFVITVALAPP
GR
>Mature_242_residues
MELLRAFLDVLFPPLCHLCKAPVPGAGPLHLCDACLGAMTPITSPLCPVCGVPHRTEGGIDHLCGSCMLTPPPFDGVRGA
LLFDGPLQELIHRHKYGHKVHLRRPLALLAIRHLTPFVQSVAPDVIIPVPLHRSRLRERGFNQAVLVGAVLSREWRLPLL
RHTLRRVRPTVAQVTLSARERRANVRGAFAVSGPAGIAGRRVLLMDDVVTTGSTVAECARVLKDAGASAVFVITVALAPP
GR

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=224, Percent_Identity=37.0535714285714, Blast_Score=111, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26083; Mature: 26083

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLRAFLDVLFPPLCHLCKAPVPGAGPLHLCDACLGAMTPITSPLCPVCGVPHRTEGGI
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DHLCGSCMLTPPPFDGVRGALLFDGPLQELIHRHKYGHKVHLRRPLALLAIRHLTPFVQS
HHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
VAPDVIIPVPLHRSRLRERGFNQAVLVGAVLSREWRLPLLRHTLRRVRPTVAQVTLSARE
HCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRANVRGAFAVSGPAGIAGRRVLLMDDVVTTGSTVAECARVLKDAGASAVFVITVALAPP
HHCCCCEEEEECCCCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCC
GR
CC
>Mature Secondary Structure
MELLRAFLDVLFPPLCHLCKAPVPGAGPLHLCDACLGAMTPITSPLCPVCGVPHRTEGGI
CHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCH
DHLCGSCMLTPPPFDGVRGALLFDGPLQELIHRHKYGHKVHLRRPLALLAIRHLTPFVQS
HHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
VAPDVIIPVPLHRSRLRERGFNQAVLVGAVLSREWRLPLLRHTLRRVRPTVAQVTLSARE
HCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RRANVRGAFAVSGPAGIAGRRVLLMDDVVTTGSTVAECARVLKDAGASAVFVITVALAPP
HHCCCCEEEEECCCCCCCCCEEEEECCHHHCCHHHHHHHHHHHHCCCCEEEEEEEEECCC
GR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]