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The map label for this gene is uppP

Identifier: 78224325

GI number: 78224325

Start: 3529781

End: 3530590

Strand: Direct

Name: uppP

Synonym: Gmet_3133

Alternate gene names: 78224325

Gene position: 3529781-3530590 (Clockwise)

Preceding gene: 78224322

Following gene: 78224326

Centisome position: 88.3

GC content: 64.07

Gene sequence:

>810_bases
ATGAATCCCCTTCACGCAACAGTTCTCGGAGCCATTCAGGGTCTCACCGAAGTGCTCCCCGTCAGCAGTTCAGCGCACCT
GATTCTCATTCCCTGGCTCTTCGGGTGGCCCGAATCGGGGATCACCTTCGACGTGGCCCTCCATCTGGGAACCCTCATCG
CTCTCGCCCTCTACTTCCGCCGCGACATCGCCGAACTGGTCGTGAATGCCCTCTCGGGCCTCACAGGGGGGGCACACTCC
TCCGCCACCCGGCTTCCCTGGTACATCATCGCCGGCTGCGTCCCCGCCGCCATCGTCGGAAAGACCCTCGAAGAGCCCAT
CGAAGCGATCTTCCGCGCCAACCCGGCCATTATCGCCGCTTTCCTGATCGGCTTCGGGCTTCTGCTGGCCCTGGCGGACA
CCCTCGGTTCGAAAAAGTCGCGCATGGACCAGATCGACCTCAAGAACGCCATGATGATCGGTCTCGCCCAGTGCCTAGCG
CTCCTCCCCGGCGTCTCCCGCTCGGGGATCACCATCACCGCGGCGCTCTTCCTCGGCTTCAGCCGGGAAACGGCGGCCCG
GTTTTCTTTCCTCCTCTCCCTCCCCATCGTGGCCGGAGCGGCGCTCCTGAAGGTGGGGCACCTGGTGCGGCACGGCGTTC
CCGAAGGGGAACTGCAGCCGCTCCTGATCGGCGTCGGCGTCTCGGCAGTGTTCGGCTATGTGAGCGTCGCCCTCCTCCTC
AAGCTGGTGCAGCGCTACTCGCTCTACCCCTTTGTCTGGTACCGGCTCCTGGCAGGGGCAGGAGTGCTACTCTTCATCTT
CAACCAATAA

Upstream 100 bases:

>100_bases
CTGCGTTACAACTCCGTGTACTTCACTCCACTCTTTGACTTGTAGCGACACATCGGTTACGCTACGACGCTCACTTCAGG
ACGCCAAGGAGAAAGCAGTC

Downstream 100 bases:

>100_bases
AACATCCTGAGCCTCTTTTCATTATTTACCACCCATGCTACAGTTCCCGCTCCCGATCCGGCACCAATCAGCAGGGAGGA
ACGACCATATGGCAGGCGGC

Product: undecaprenyl-diphosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFRRDIAELVVNALSGLTGGAHS
SATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAAFLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLA
LLPGVSRSGITITAALFLGFSRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLL
KLVQRYSLYPFVWYRLLAGAGVLLFIFNQ

Sequences:

>Translated_269_residues
MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFRRDIAELVVNALSGLTGGAHS
SATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAAFLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLA
LLPGVSRSGITITAALFLGFSRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLL
KLVQRYSLYPFVWYRLLAGAGVLLFIFNQ
>Mature_269_residues
MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFRRDIAELVVNALSGLTGGAHS
SATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAAFLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLA
LLPGVSRSGITITAALFLGFSRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLL
KLVQRYSLYPFVWYRLLAGAGVLLFIFNQ

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=276, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_GEOMG (Q39QX7)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_386072.1
- STRING:   Q39QX7
- GeneID:   3740907
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3133
- NMPDR:   fig|269799.3.peg.2367
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- PhylomeDB:   Q39QX7
- ProtClustDB:   CLSK827794
- BioCyc:   GMET269799:GMET_3133-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 28565; Mature: 28565

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x156c4b5c)-; HASH(0x15172410)-; HASH(0x151722fc)-; HASH(0x15705914)-; HASH(0x159290f0)-; HASH(0x15934690)-; HASH(0x159a1fa0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFR
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RDIAELVVNALSGLTGGAHSSATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLALLPGVSRSGITITAALFLGF
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
SRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHHH
KLVQRYSLYPFVWYRLLAGAGVLLFIFNQ
HHHHHHCCHHHHHHHHHHCCCEEEEEECH
>Mature Secondary Structure
MNPLHATVLGAIQGLTEVLPVSSSAHLILIPWLFGWPESGITFDVALHLGTLIALALYFR
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
RDIAELVVNALSGLTGGAHSSATRLPWYIIAGCVPAAIVGKTLEEPIEAIFRANPAIIAA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
FLIGFGLLLALADTLGSKKSRMDQIDLKNAMMIGLAQCLALLPGVSRSGITITAALFLGF
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
SRETAARFSFLLSLPIVAGAALLKVGHLVRHGVPEGELQPLLIGVGVSAVFGYVSVALLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEHHHHHHHHHHHHHHHHH
KLVQRYSLYPFVWYRLLAGAGVLLFIFNQ
HHHHHHCCHHHHHHHHHHCCCEEEEEECH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA