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The map label for this gene is macB [H]

Identifier: 78224229

GI number: 78224229

Start: 3421619

End: 3422848

Strand: Reverse

Name: macB [H]

Synonym: Gmet_3036

Alternate gene names: 78224229

Gene position: 3422848-3421619 (Counterclockwise)

Preceding gene: 78224230

Following gene: 78224227

Centisome position: 85.63

GC content: 64.31

Gene sequence:

>1230_bases
ATGACGACCCTCTGGCAAAGTCTCCTGATCGCCCTCCGGGCGCTGCGGGTCAACAAGATGCGGGCACTCCTGACCATGCT
TGGCATCATCATCGGGATCGCCGCCGTCATCGCCATGGTGGCCATTGGTGCCGGGGCGAGCAAGATGATCTCCGACCAGA
TCTCCAGCATCGGGAGCAACCTCCTCCTGGTCCTTCCCGGCTCCACCACCAGCGGGGGGCTGCGGACCGGGGCCGGCGGC
ACCCCGACCCTCACCTACGACGACGCCCGGGCCATCAAGGCGGAATGCCCGTCGGTGGAGAATGTGGCCCCTACGGTGCG
GGGCTCGGCCCAGATCGTCTACGGCAATCAGAACTGGTCCACCATCGTCATGGGGTGCACCCCCGAGATGGTCGTCGTCC
GGGACTGGTCCCTGACAACCGGCAGAAACATCTCTCTGTCCGATGTGGACGGCGCCACCAAGAACTGTCTCATTGGCCAG
ACCGTGGCCGAGAACCTTTTCGGCGATGCTGATCCCATCGGCAAGATCATCCGGATCAAGAAGATACCGTTCACCGTCAT
CGGGATACTGGACCACAAGGGGCAGTCTCCCCAGGGGACAGATCAGGACGACGTGATCTTCGTGCCGCTGCGCACTGCCC
AGCGCAAGCTCTTCGGCAGCCAGTTCCCCAACACGGTGGGCGCCATGATGATCCAGGCGAAAAGCGCCGATGTTCTCAAA
AAGGCCGAGGAAGAGGTGACCGCGCTCCTGGACCAGCGCCACCGGATCGGTCCGAGCCGGGAGCGGGACTTCACGGTGCG
CAACCTGTCGGAGATCCTCGCGGTATCGGAACAGTCCTCCAAGGTCATGTCGATCCTCCTGGGGGCCGTGGCCTCCATCT
CCCTGGTCGTCGGCGGCATCGGCATCATGAACATCATGCTTGTCTCGGTCACGGAGCGGACCCGGGAGATCGGCATCCGG
ATGGCCATCGGCGCCAAACAACGGGACATCCTCCTCCAGTTCCTGACCGAGGCGGTGCTCCTCACCACGGCGGGGGGGAT
CATCGGCATGGGGCTCGGGGTGGCGGGGGCCATGGCGGTCTCGAAGATCATGCAGTGGCCGACCCTGATCTCCACGCAGG
CAATCATCATCGCTTTCCTCTTCTCCGCCGGCGTCGGCGTCTTCTTCGGCTTCTACCCGGCCCGCAAGGCGGCCAACCTG
AACCCCATCGAGGCGCTGCGGTACGAGTGA

Upstream 100 bases:

>100_bases
CCTTCACCGGCCGCCATCTCGTCTTCCGGGACGGCACCATCATCGCCGATTCGCCGAACGCCTCCCCTGCCGTGGCGTCG
CCGGCCCAGGGAGAGGCCCC

Downstream 100 bases:

>100_bases
GTCCCGCCAGGGACGCAATGAACGAAAAAAGGGGAAAGGCTGGTCGGCCTTTCCCCTTTTTCGCTCTATCCATCTTGTTC
TGAATGGTTCCTATTCCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTTLWQSLLIALRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRTGAGG
TPTLTYDDARAIKAECPSVENVAPTVRGSAQIVYGNQNWSTIVMGCTPEMVVVRDWSLTTGRNISLSDVDGATKNCLIGQ
TVAENLFGDADPIGKIIRIKKIPFTVIGILDHKGQSPQGTDQDDVIFVPLRTAQRKLFGSQFPNTVGAMMIQAKSADVLK
KAEEEVTALLDQRHRIGPSRERDFTVRNLSEILAVSEQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIR
MAIGAKQRDILLQFLTEAVLLTTAGGIIGMGLGVAGAMAVSKIMQWPTLISTQAIIIAFLFSAGVGVFFGFYPARKAANL
NPIEALRYE

Sequences:

>Translated_409_residues
MTTLWQSLLIALRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRTGAGG
TPTLTYDDARAIKAECPSVENVAPTVRGSAQIVYGNQNWSTIVMGCTPEMVVVRDWSLTTGRNISLSDVDGATKNCLIGQ
TVAENLFGDADPIGKIIRIKKIPFTVIGILDHKGQSPQGTDQDDVIFVPLRTAQRKLFGSQFPNTVGAMMIQAKSADVLK
KAEEEVTALLDQRHRIGPSRERDFTVRNLSEILAVSEQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIR
MAIGAKQRDILLQFLTEAVLLTTAGGIIGMGLGVAGAMAVSKIMQWPTLISTQAIIIAFLFSAGVGVFFGFYPARKAANL
NPIEALRYE
>Mature_408_residues
TTLWQSLLIALRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSNLLLVLPGSTTSGGLRTGAGGT
PTLTYDDARAIKAECPSVENVAPTVRGSAQIVYGNQNWSTIVMGCTPEMVVVRDWSLTTGRNISLSDVDGATKNCLIGQT
VAENLFGDADPIGKIIRIKKIPFTVIGILDHKGQSPQGTDQDDVIFVPLRTAQRKLFGSQFPNTVGAMMIQAKSADVLKK
AEEEVTALLDQRHRIGPSRERDFTVRNLSEILAVSEQSSKVMSILLGAVASISLVVGGIGIMNIMLVSVTERTREIGIRM
AIGAKQRDILLQFLTEAVLLTTAGGIIGMGLGVAGAMAVSKIMQWPTLISTQAIIIAFLFSAGVGVFFGFYPARKAANLN
PIEALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=406, Percent_Identity=36.6995073891626, Blast_Score=222, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 43469; Mature: 43337

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLWQSLLIALRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LLLVLPGSTTSGGLRTGAGGTPTLTYDDARAIKAECPSVENVAPTVRGSAQIVYGNQNWS
EEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
TIVMGCTPEMVVVRDWSLTTGRNISLSDVDGATKNCLIGQTVAENLFGDADPIGKIIRIK
EEEEECCCCEEEEEECCCCCCCCCEECCCCCCCCCCEEHHHHHHHHCCCCCCCCCEEEEE
KIPFTVIGILDHKGQSPQGTDQDDVIFVPLRTAQRKLFGSQFPNTVGAMMIQAKSADVLK
ECCEEEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHEECCCHHHHH
KAEEEVTALLDQRHRIGPSRERDFTVRNLSEILAVSEQSSKVMSILLGAVASISLVVGGI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVSVTERTREIGIRMAIGAKQRDILLQFLTEAVLLTTAGGIIGMGLGVAGAMAV
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SKIMQWPTLISTQAIIIAFLFSAGVGVFFGFYPARKAANLNPIEALRYE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
TTLWQSLLIALRALRVNKMRALLTMLGIIIGIAAVIAMVAIGAGASKMISDQISSIGSN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
LLLVLPGSTTSGGLRTGAGGTPTLTYDDARAIKAECPSVENVAPTVRGSAQIVYGNQNWS
EEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCCCCCCCCCCCCCEEEEEECCCCC
TIVMGCTPEMVVVRDWSLTTGRNISLSDVDGATKNCLIGQTVAENLFGDADPIGKIIRIK
EEEEECCCCEEEEEECCCCCCCCCEECCCCCCCCCCEEHHHHHHHHCCCCCCCCCEEEEE
KIPFTVIGILDHKGQSPQGTDQDDVIFVPLRTAQRKLFGSQFPNTVGAMMIQAKSADVLK
ECCEEEEEEEECCCCCCCCCCCCCEEEEECHHHHHHHHHHCCCHHHHHHHEECCCHHHHH
KAEEEVTALLDQRHRIGPSRERDFTVRNLSEILAVSEQSSKVMSILLGAVASISLVVGGI
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIMNIMLVSVTERTREIGIRMAIGAKQRDILLQFLTEAVLLTTAGGIIGMGLGVAGAMAV
HHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
SKIMQWPTLISTQAIIIAFLFSAGVGVFFGFYPARKAANLNPIEALRYE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA