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The map label for this gene is dtd

Identifier: 78224201

GI number: 78224201

Start: 3392265

End: 3392720

Strand: Direct

Name: dtd

Synonym: Gmet_3008

Alternate gene names: 78224201

Gene position: 3392265-3392720 (Clockwise)

Preceding gene: 78224200

Following gene: 78224202

Centisome position: 84.86

GC content: 65.13

Gene sequence:

>456_bases
ATGAAGGCGGTTATCCAGCGGGTAAGCGAGGCCAGGGTGGTGGTGGACGGCGAGGTTGTGGGAGCCATCGAGCGGGGAAT
TCTGGTCCTTCTCGGGGTGGAGAAGGGGGACGCGGAGCGGGACGCGGCATGGCTGGCGGAAAAGGTCGCGGGGCTGCGGA
TTTTCGAGGACGAGGCGGGGAAGATGAACCTGTCGGTGCGGGAGGTGACCGGCGGGATCCTCGCCGTGTCCCAGTTTACC
CTGGCGGGGAACTGCGCCAAGGGGCGGCGCCCATCCTTCGACACGGCGGCACCACCCGACGAGGGGAAGCGGCTCTATGG
CCGTTTCGTTGATTTCATGCGGGAAACCGGCATCCCCACGGCCACGGGGATCTTCCAGGCGGACATGAAGGTGCATCTGG
TGAACGACGGGCCGGTGACATTTATCCTGGAGAGTCCGAAGGCTACCGGGGGATAA

Upstream 100 bases:

>100_bases
CGCTGGAGCGCTATCCGGAGCTAGCGCGGGTGATCTTCACCCCCTTCGGTGCCGAGGCGGAGGCCGCCTACCGGGCTGCC
CTGGCGAAGGTGTTCGGCGC

Downstream 100 bases:

>100_bases
TCCCCACGGCGATCATGGTCCCTTCCTCGATCCGCGAAGGTGCTCGCTCGCCGCCCCCTCCAGGGCTTCGTCCAGGTCGG
CAGCGGTGCCAGCATGGGCT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MKAVIQRVSEARVVVDGEVVGAIERGILVLLGVEKGDAERDAAWLAEKVAGLRIFEDEAGKMNLSVREVTGGILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYGRFVDFMRETGIPTATGIFQADMKVHLVNDGPVTFILESPKATGG

Sequences:

>Translated_151_residues
MKAVIQRVSEARVVVDGEVVGAIERGILVLLGVEKGDAERDAAWLAEKVAGLRIFEDEAGKMNLSVREVTGGILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYGRFVDFMRETGIPTATGIFQADMKVHLVNDGPVTFILESPKATGG
>Mature_151_residues
MKAVIQRVSEARVVVDGEVVGAIERGILVLLGVEKGDAERDAAWLAEKVAGLRIFEDEAGKMNLSVREVTGGILAVSQFT
LAGNCAKGRRPSFDTAAPPDEGKRLYGRFVDFMRETGIPTATGIFQADMKVHLVNDGPVTFILESPKATGG

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=46, Blast_Score=120, Evalue=5e-28,
Organism=Escherichia coli, GI1790320, Length=144, Percent_Identity=55.5555555555556, Blast_Score=153, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI115533292, Length=148, Percent_Identity=41.2162162162162, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=40, Blast_Score=107, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281361569, Length=149, Percent_Identity=41.6107382550336, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DTD_GEOMG (Q39RA1)

Other databases:

- EMBL:   CP000148
- RefSeq:   YP_385948.1
- HSSP:   O66742
- ProteinModelPortal:   Q39RA1
- SMR:   Q39RA1
- STRING:   Q39RA1
- GeneID:   3740997
- GenomeReviews:   CP000148_GR
- KEGG:   gme:Gmet_3008
- NMPDR:   fig|269799.3.peg.2885
- eggNOG:   COG1490
- HOGENOM:   HBG286048
- OMA:   MKAVIQR
- PhylomeDB:   Q39RA1
- ProtClustDB:   PRK05273
- BioCyc:   GMET269799:GMET_3008-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00518
- InterPro:   IPR003732
- Gene3D:   G3DSA:3.50.80.10
- PANTHER:   PTHR10472
- TIGRFAMs:   TIGR00256

Pfam domain/function: PF02580 Tyr_Deacylase; SSF69500 DTyrtRNA_deacyls

EC number: NA

Molecular weight: Translated: 16116; Mature: 16116

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: ACT_SITE 80-80

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVIQRVSEARVVVDGEVVGAIERGILVLLGVEKGDAERDAAWLAEKVAGLRIFEDEAG
CHHHHHHHHHCEEEECCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCC
KMNLSVREVTGGILAVSQFTLAGNCAKGRRPSFDTAAPPDEGKRLYGRFVDFMRETGIPT
EEEEEHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGIFQADMKVHLVNDGPVTFILESPKATGG
CCCEEEECEEEEEECCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKAVIQRVSEARVVVDGEVVGAIERGILVLLGVEKGDAERDAAWLAEKVAGLRIFEDEAG
CHHHHHHHHHCEEEECCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEEECCCC
KMNLSVREVTGGILAVSQFTLAGNCAKGRRPSFDTAAPPDEGKRLYGRFVDFMRETGIPT
EEEEEHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
ATGIFQADMKVHLVNDGPVTFILESPKATGG
CCCEEEECEEEEEECCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA