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The map label for this gene is clpB [H]

Identifier: 78224047

GI number: 78224047

Start: 3228780

End: 3231374

Strand: Reverse

Name: clpB [H]

Synonym: Gmet_2851

Alternate gene names: 78224047

Gene position: 3231374-3228780 (Counterclockwise)

Preceding gene: 78224048

Following gene: 78224046

Centisome position: 80.84

GC content: 64.62

Gene sequence:

>2595_bases
ATGATTCGACCCGAAAAAATGACCATAAAGACCCAGGAGGCCCTGGCCGGCGCCCAGCAGCTCGCCGCGCGGCAGGGAAA
CGGCACCATCGAACCGGAACATCTCCTCGCAGCGCTCCTCGAGCAGGAAGGGGGGCTTGTGGCCCCGATCCTCCAGAAGG
TGGGAGCCGCGCCTGCCTCCCTGCGGAGCTCCGTTGACGCGCTCCTTAAAAAGCTCCCCCAGGTGAGCGGCGCCACGGCC
CAGGCCTACCTCTCGCCCTCTCTGAACCGGATTCTCGACGGGGCCCAGCGGGAAGCCGATGCCATGAAGGACGAGTTCGT
CTCCACCGAGCACCTTCTCCTCGGCTTCTTCGCCGACAAACAGTGCGCGGCAACTCGGGCGCTTCTCGATGGCGGCGCCA
CCCGCGAGAACGTGCTGGCGGCGCTCGTGGAGATCCGCGGCGGCGAGCGGGTCACCGATCAGAGCCCCGAGGACAAGTAC
CAGGCTCTGACCAAGTACGCCCGGGACCTGACCGACCTGGCCCGCCAGGGGAAGCTTGACCCGGTTATCGGCCGGGATGA
TGAAATCCGGCGGGTGCTGCAGGTCCTGTCCCGGCGCACCAAGAACAACCCGGTCCTCATCGGTGAGCCGGGGGTGGGGA
AGACCGCCATCGTGGAGGGGCTCGCCCAGCGGATTGTCTCGGGGGACGTGCCGGAATCCCTGAAGGATAAGCGCCTCGTG
GCCCTCGACATGGGGGCCCTCATCGCCGGCGCCAAGTATCGGGGGGAGTTCGAGGAGCGGCTCAAGGCGGTTATCAAGGA
GGTGGCCAAGTCCGAGGGAAAGGTGATCCTCTTCATTGACGAGCTCCACACCCTGGTGGGGGCCGGAGCCGCCGAGGGGG
CCATGGACGCCTCCAACATGCTCAAGCCGGCCTTGGCCCGGGGGGAGCTCCACTGCATCGGCGCCACCACCCTCAACGAG
TACCGCAAGTACATCGAGAAGGACGCGGCCCTGGAGCGGCGCTTCCAGCAGGTCTACACCGGCGAGCCGAGCGTGGAGGA
CACCATTGCCATCCTCCGGGGGCTCAAGGAGAAGTACGAGACCTACCACGGCATCCGGATCAAGGACAGCGCCATCATCG
CCGCCGCCACGCTTTCGGACCGCTACATCACCGACCGCTTCCTCCCCGACAAGGCCATCGACCTCATCGACGAGGCCGCC
TCGCGCCTGAGGATCGAGATTGACTCCATGCCAACCGAGATCGACGAGGTGGAGCGGAAGATCATCCAACTGGAGATCGA
GAAGCAGGCGCTTTTGCGGGAGCAGGACCCCCACGCCCTGGAGCGTCTCCAGAAGCTGACTGACGAGCTGAACGGGCTCC
AGGCCCAAGCGGCGGAGCTGAAGGCCCACTGGCGGCAGGAGAAGGAAATTATCAAGGGACTCAGCGAACTGAAGCAGCAG
CTTGAGGAGAGGAAAGAGCAGGCGAAGAAGGCCGAGCGGGAGGGGAACCTGGCCCGTACCGCGGAGATCCGCTATGGAGA
GATTCCTGCCATCGAGAAGGAAATGGAGGAGAAGAAGCAGCAACTGGAGGCGCTCCAGAAGGAAGGGAAGATGCTCCCCG
AAGAGGTTGATGGCGAACTGGTGGCTGAAATCGTCTCCCGCTGGACTGGTGTTCCGGTCTCACGCATGATGGAGGGGGAG
GCGGACAAGCTCGTGCACATGGAGGAGCGGCTCAAGACCCGCGTGGTGGGCCAGAACGACGCCCTGCTGCTGGTGGCCAA
CGCCATCCGCCGCGCCCGGTCGGGGCTCTCGGACCCCAACCGCCCCATCGGCTCCTTCCTCTTCCTGGGCCCCACCGGGG
TCGGGAAGACCGAAACCGCCAAGGCCCTGGCCGAGTTCCTCTTCAACGACGACCAGGCCATTGTCCGGATCGACATGAGC
GAGTACCAGGAAAAACACACCGTGGCCCGGCTCATCGGTGCGCCCCCCGGCTACGTCGGCTACGAGGAGGGGGGGCAGCT
CACGGAAGCGGTCAAGCGCCGCCCCTACTCCATCGTCCTTTTCGACGAAATCGAGAAGGCCCATGCCGAGGTGTTCAACG
TCCTCCTCCAGGTGCTCGATGACGGCCGGCTCACCGACGGCCAGGGGCGGACAGTGGATTTCCGCAATACGGTCATCATC
ATGACGAGCAACCTGGGCTCCCAGTGGATCCAGCAGTATGGCGCCAGCGACTACACCCGCATGAAGCAGATGGTGACCGA
GACCCTGCGGGAGAGCTTCAAACCCGAGTTCCTGAACCGGATCGACGAGGTGGTCATCTACCACGCGCTGCCGCTCGAGC
GGATCAAGCAGATCATCGACATCCAGATCCAAGGGCTGAAGAAGCGCCTCGCCGAGCGGCACATCACCCTGGAGATCACC
GACAAGGCACGGGAATACCTGGCCCAGGAGGGGTACGATCCAGCCTACGGAGCACGGCCCCTCAAGCGGGCGATCCAGCG
CAAGGTTCAGGACCCCCTGGCCCTCATGCTCCTCGAAGGGAAGTTCCGGGAGGGGGACACCATCCGGGCCGACCTCTCCC
ATGGCGGAGAAGGGCTCGTCATTACGAAAAAATAA

Upstream 100 bases:

>100_bases
TTTCCTCCCCCTGATCCCCCCACAATTCATGTTTCCCCTTCCTTGACTTCCCCCCGGGGCGTGCCTATGTTTTTCCTGTA
CTAGGAAAGGAGAGCGCCCC

Downstream 100 bases:

>100_bases
TAATCTCCTGCAGACGGGTTACTGTAGCGGGTCGTCCTTTTCGGGAGCGGCCCGCTTTTTTCTTCACAGTTGCTGCGGTT
GGGGCTAGGATTGCCGAAAA

Product: AAA ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 864; Mature: 864

Protein sequence:

>864_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGTIEPEHLLAALLEQEGGLVAPILQKVGAAPASLRSSVDALLKKLPQVSGATA
QAYLSPSLNRILDGAQREADAMKDEFVSTEHLLLGFFADKQCAATRALLDGGATRENVLAALVEIRGGERVTDQSPEDKY
QALTKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPESLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIKEVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYETYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERKIIQLEIEKQALLREQDPHALERLQKLTDELNGLQAQAAELKAHWRQEKEIIKGLSELKQQ
LEERKEQAKKAEREGNLARTAEIRYGEIPAIEKEMEEKKQQLEALQKEGKMLPEEVDGELVAEIVSRWTGVPVSRMMEGE
ADKLVHMEERLKTRVVGQNDALLLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMS
EYQEKHTVARLIGAPPGYVGYEEGGQLTEAVKRRPYSIVLFDEIEKAHAEVFNVLLQVLDDGRLTDGQGRTVDFRNTVII
MTSNLGSQWIQQYGASDYTRMKQMVTETLRESFKPEFLNRIDEVVIYHALPLERIKQIIDIQIQGLKKRLAERHITLEIT
DKAREYLAQEGYDPAYGARPLKRAIQRKVQDPLALMLLEGKFREGDTIRADLSHGGEGLVITKK

Sequences:

>Translated_864_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGTIEPEHLLAALLEQEGGLVAPILQKVGAAPASLRSSVDALLKKLPQVSGATA
QAYLSPSLNRILDGAQREADAMKDEFVSTEHLLLGFFADKQCAATRALLDGGATRENVLAALVEIRGGERVTDQSPEDKY
QALTKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPESLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIKEVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYETYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERKIIQLEIEKQALLREQDPHALERLQKLTDELNGLQAQAAELKAHWRQEKEIIKGLSELKQQ
LEERKEQAKKAEREGNLARTAEIRYGEIPAIEKEMEEKKQQLEALQKEGKMLPEEVDGELVAEIVSRWTGVPVSRMMEGE
ADKLVHMEERLKTRVVGQNDALLLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMS
EYQEKHTVARLIGAPPGYVGYEEGGQLTEAVKRRPYSIVLFDEIEKAHAEVFNVLLQVLDDGRLTDGQGRTVDFRNTVII
MTSNLGSQWIQQYGASDYTRMKQMVTETLRESFKPEFLNRIDEVVIYHALPLERIKQIIDIQIQGLKKRLAERHITLEIT
DKAREYLAQEGYDPAYGARPLKRAIQRKVQDPLALMLLEGKFREGDTIRADLSHGGEGLVITKK
>Mature_864_residues
MIRPEKMTIKTQEALAGAQQLAARQGNGTIEPEHLLAALLEQEGGLVAPILQKVGAAPASLRSSVDALLKKLPQVSGATA
QAYLSPSLNRILDGAQREADAMKDEFVSTEHLLLGFFADKQCAATRALLDGGATRENVLAALVEIRGGERVTDQSPEDKY
QALTKYARDLTDLARQGKLDPVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPESLKDKRLV
ALDMGALIAGAKYRGEFEERLKAVIKEVAKSEGKVILFIDELHTLVGAGAAEGAMDASNMLKPALARGELHCIGATTLNE
YRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYETYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAA
SRLRIEIDSMPTEIDEVERKIIQLEIEKQALLREQDPHALERLQKLTDELNGLQAQAAELKAHWRQEKEIIKGLSELKQQ
LEERKEQAKKAEREGNLARTAEIRYGEIPAIEKEMEEKKQQLEALQKEGKMLPEEVDGELVAEIVSRWTGVPVSRMMEGE
ADKLVHMEERLKTRVVGQNDALLLVANAIRRARSGLSDPNRPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMS
EYQEKHTVARLIGAPPGYVGYEEGGQLTEAVKRRPYSIVLFDEIEKAHAEVFNVLLQVLDDGRLTDGQGRTVDFRNTVII
MTSNLGSQWIQQYGASDYTRMKQMVTETLRESFKPEFLNRIDEVVIYHALPLERIKQIIDIQIQGLKKRLAERHITLEIT
DKAREYLAQEGYDPAYGARPLKRAIQRKVQDPLALMLLEGKFREGDTIRADLSHGGEGLVITKK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=313, Percent_Identity=37.0607028753994, Blast_Score=218, Evalue=3e-56,
Organism=Escherichia coli, GI1788943, Length=853, Percent_Identity=59.4372801875733, Blast_Score=1018, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=387, Percent_Identity=41.343669250646, Blast_Score=281, Evalue=1e-76,
Organism=Saccharomyces cerevisiae, GI6320464, Length=707, Percent_Identity=52.6166902404526, Blast_Score=757, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=857, Percent_Identity=43.1738623103851, Blast_Score=693, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96248; Mature: 96248

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPEKMTIKTQEALAGAQQLAARQGNGTIEPEHLLAALLEQEGGLVAPILQKVGAAPAS
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHH
LRSSVDALLKKLPQVSGATAQAYLSPSLNRILDGAQREADAMKDEFVSTEHLLLGFFADK
HHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCH
QCAATRALLDGGATRENVLAALVEIRGGERVTDQSPEDKYQALTKYARDLTDLARQGKLD
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPESLKDKRLV
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCEEE
ALDMGALIAGAKYRGEFEERLKAVIKEVAKSEGKVILFIDELHTLVGAGAAEGAMDASNM
EEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHCIGATTLNEYRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYE
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAASRLRIEIDSMPTEIDEVERK
HHCCEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
IIQLEIEKQALLREQDPHALERLQKLTDELNGLQAQAAELKAHWRQEKEIIKGLSELKQQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEERKEQAKKAEREGNLARTAEIRYGEIPAIEKEMEEKKQQLEALQKEGKMLPEEVDGEL
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHH
VAEIVSRWTGVPVSRMMEGEADKLVHMEERLKTRVVGQNDALLLVANAIRRARSGLSDPN
HHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
RPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMSEYQEKHTVARLIGAPPGYVG
CCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCC
YEEGGQLTEAVKRRPYSIVLFDEIEKAHAEVFNVLLQVLDDGRLTDGQGRTVDFRNTVII
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNLGSQWIQQYGASDYTRMKQMVTETLRESFKPEFLNRIDEVVIYHALPLERIKQIID
EECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
IQIQGLKKRLAERHITLEITDKAREYLAQEGYDPAYGARPLKRAIQRKVQDPLALMLLEG
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCC
KFREGDTIRADLSHGGEGLVITKK
CCCCCCCEEEECCCCCCEEEEECC
>Mature Secondary Structure
MIRPEKMTIKTQEALAGAQQLAARQGNGTIEPEHLLAALLEQEGGLVAPILQKVGAAPAS
CCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCHHH
LRSSVDALLKKLPQVSGATAQAYLSPSLNRILDGAQREADAMKDEFVSTEHLLLGFFADK
HHHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCH
QCAATRALLDGGATRENVLAALVEIRGGERVTDQSPEDKYQALTKYARDLTDLARQGKLD
HHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PVIGRDDEIRRVLQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVSGDVPESLKDKRLV
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCEEE
ALDMGALIAGAKYRGEFEERLKAVIKEVAKSEGKVILFIDELHTLVGAGAAEGAMDASNM
EEEHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCHHHH
LKPALARGELHCIGATTLNEYRKYIEKDAALERRFQQVYTGEPSVEDTIAILRGLKEKYE
HHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
TYHGIRIKDSAIIAAATLSDRYITDRFLPDKAIDLIDEAASRLRIEIDSMPTEIDEVERK
HHCCEEEECCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
IIQLEIEKQALLREQDPHALERLQKLTDELNGLQAQAAELKAHWRQEKEIIKGLSELKQQ
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEERKEQAKKAEREGNLARTAEIRYGEIPAIEKEMEEKKQQLEALQKEGKMLPEEVDGEL
HHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHH
VAEIVSRWTGVPVSRMMEGEADKLVHMEERLKTRVVGQNDALLLVANAIRRARSGLSDPN
HHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCC
RPIGSFLFLGPTGVGKTETAKALAEFLFNDDQAIVRIDMSEYQEKHTVARLIGAPPGYVG
CCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCCC
YEEGGQLTEAVKRRPYSIVLFDEIEKAHAEVFNVLLQVLDDGRLTDGQGRTVDFRNTVII
CCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCEEEE
MTSNLGSQWIQQYGASDYTRMKQMVTETLRESFKPEFLNRIDEVVIYHALPLERIKQIID
EECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
IQIQGLKKRLAERHITLEITDKAREYLAQEGYDPAYGARPLKRAIQRKVQDPLALMLLEG
HHHHHHHHHHHHCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHCCC
KFREGDTIRADLSHGGEGLVITKK
CCCCCCCEEEECCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA