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The map label for this gene is arsM

Identifier: 78223987

GI number: 78223987

Start: 3155720

End: 3156520

Strand: Reverse

Name: arsM

Synonym: Gmet_2791

Alternate gene names: 78223987

Gene position: 3156520-3155720 (Counterclockwise)

Preceding gene: 78223988

Following gene: 78223984

Centisome position: 78.96

GC content: 52.18

Gene sequence:

>801_bases
ATGGACAAGCAAAGGAATGAAGAGATTCGCGGTGCAGTTCGGGAGAATTATGGAAAGGTTGCCGTATCAGGTGGGGCAGG
TTGCGGTTGCTCTTCTTCATCGTGCTGTGGAACGCCTAATGGTGCTACGACAGAAGACATCTCGCTTGGCTTGGGTTACT
CAGGCGAAGATGTGGCGGCTGTTCCTGAGGGTGCGAACCTGGGGCTTGGGTGCGGCAATCCGCAGGCCATTGCGTCTTTG
CAGCTTGGCGAAACGGTGCTCGACCTTGGTAGCGGCGGAGGGTTCGACTGCTTCCTTGCGGCTCGGGCTGTCGGCCACAC
AGGACATGTCATAGGAGTTGACATGACGCCGGAAATGATTACGAAGTCCCGCCGCAATGCGGATAAAGCCAATTTCGGGA
ACGTCGATTTTCGATTAGGGGAGTTGGAAAACCTTCCGGTTGCCGATGGCATTGTGGACGTCATCATCTCGAATTGTGTA
ATCAACCTATCTCCAGAAAAAGCAAAGGTGTTTAGCGAGTCCTTCCGTGTCTTGAAGTCGGGCGGACGGCTGGCAATTTC
CGATGTAGTTGCCACCGCCGAAATGCCCGGGGACATTAAAAATAATATGGCGTTCCACACCGGATGCATAGCAGGCGCAT
CTTCGATCGAGGAAATTGAATCCATGTTGGAGCGAACCGGCTTCGTGAATATTCGAATCAATCCAAAAACGGAGAGCAGA
GCATTCATCCGTGACTGGATGCCGGGAAGCAAAATAGAGGACTATGTAGTTTCGGCAACTATCGAAGCAATAAAACCATA
G

Upstream 100 bases:

>100_bases
ATGCTTGCTGATTACCAGCAGCGTTAATGTTGCGTCCTTTTTGATCTTTTGCCGTCTATAGGGTGAGCGCTGCTCATAAA
CCCTATTGAGGAGGTGCAAA

Downstream 100 bases:

>100_bases
GCATAACAAAGCGCGCCAGACGGTCGGCGCGGTGAACCCGCGCCGCCGCTGCGCCCTCAGCCGTTGGCAGATTATGGGCC
GTTGCGTCATGCGAAAATAC

Product: arsenite S-adenosylmethyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MDKQRNEEIRGAVRENYGKVAVSGGAGCGCSSSSCCGTPNGATTEDISLGLGYSGEDVAAVPEGANLGLGCGNPQAIASL
QLGETVLDLGSGGGFDCFLAARAVGHTGHVIGVDMTPEMITKSRRNADKANFGNVDFRLGELENLPVADGIVDVIISNCV
INLSPEKAKVFSESFRVLKSGGRLAISDVVATAEMPGDIKNNMAFHTGCIAGASSIEEIESMLERTGFVNIRINPKTESR
AFIRDWMPGSKIEDYVVSATIEAIKP

Sequences:

>Translated_266_residues
MDKQRNEEIRGAVRENYGKVAVSGGAGCGCSSSSCCGTPNGATTEDISLGLGYSGEDVAAVPEGANLGLGCGNPQAIASL
QLGETVLDLGSGGGFDCFLAARAVGHTGHVIGVDMTPEMITKSRRNADKANFGNVDFRLGELENLPVADGIVDVIISNCV
INLSPEKAKVFSESFRVLKSGGRLAISDVVATAEMPGDIKNNMAFHTGCIAGASSIEEIESMLERTGFVNIRINPKTESR
AFIRDWMPGSKIEDYVVSATIEAIKP
>Mature_266_residues
MDKQRNEEIRGAVRENYGKVAVSGGAGCGCSSSSCCGTPNGATTEDISLGLGYSGEDVAAVPEGANLGLGCGNPQAIASL
QLGETVLDLGSGGGFDCFLAARAVGHTGHVIGVDMTPEMITKSRRNADKANFGNVDFRLGELENLPVADGIVDVIISNCV
INLSPEKAKVFSESFRVLKSGGRLAISDVVATAEMPGDIKNNMAFHTGCIAGASSIEEIESMLERTGFVNIRINPKTESR
AFIRDWMPGSKIEDYVVSATIEAIKP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Homo sapiens, GI109389364, Length=242, Percent_Identity=31.8181818181818, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27819; Mature: 27819

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKQRNEEIRGAVRENYGKVAVSGGAGCGCSSSSCCGTPNGATTEDISLGLGYSGEDVAA
CCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEE
VPEGANLGLGCGNPQAIASLQLGETVLDLGSGGGFDCFLAARAVGHTGHVIGVDMTPEMI
CCCCCCCCCCCCCHHHHEEHHHCHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHH
TKSRRNADKANFGNVDFRLGELENLPVADGIVDVIISNCVINLSPEKAKVFSESFRVLKS
HHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHC
GGRLAISDVVATAEMPGDIKNNMAFHTGCIAGASSIEEIESMLERTGFVNIRINPKTESR
CCCEEEHHHHHHHCCCCCHHCCCEEEHHHHHCHHHHHHHHHHHHHCCEEEEEECCCCCCH
AFIRDWMPGSKIEDYVVSATIEAIKP
HHHHHCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDKQRNEEIRGAVRENYGKVAVSGGAGCGCSSSSCCGTPNGATTEDISLGLGYSGEDVAA
CCCCCCHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEE
VPEGANLGLGCGNPQAIASLQLGETVLDLGSGGGFDCFLAARAVGHTGHVIGVDMTPEMI
CCCCCCCCCCCCCHHHHEEHHHCHHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHH
TKSRRNADKANFGNVDFRLGELENLPVADGIVDVIISNCVINLSPEKAKVFSESFRVLKS
HHHHCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHCEEECCCHHHHHHHHHHHHHHC
GGRLAISDVVATAEMPGDIKNNMAFHTGCIAGASSIEEIESMLERTGFVNIRINPKTESR
CCCEEEHHHHHHHCCCCCHHCCCEEEHHHHHCHHHHHHHHHHHHHCCEEEEEECCCCCCH
AFIRDWMPGSKIEDYVVSATIEAIKP
HHHHHCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]